ID   A0A0D1YKS4_9EURO        Unreviewed;      1053 AA.
AC   A0A0D1YKS4;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KIV83432.1};
GN   ORFNames=PV11_05459 {ECO:0000313|EMBL:KIV83432.1};
OS   Exophiala sideris.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX   NCBI_TaxID=1016849 {ECO:0000313|EMBL:KIV83432.1, ECO:0000313|Proteomes:UP000053599};
RN   [1] {ECO:0000313|EMBL:KIV83432.1, ECO:0000313|Proteomes:UP000053599}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 121828 {ECO:0000313|EMBL:KIV83432.1,
RC   ECO:0000313|Proteomes:UP000053599};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA   Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Exophiala sideris CBS121828.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the FAH family. {ECO:0000256|ARBA:ARBA00010211}.
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DR   EMBL; KN846952; KIV83432.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0D1YKS4; -.
DR   STRING; 1016849.A0A0D1YKS4; -.
DR   HOGENOM; CLU_009826_0_0_1; -.
DR   OrthoDB; 1430490at2759; -.
DR   Proteomes; UP000053599; Unassembled WGS sequence.
DR   GO; GO:0016810; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd01299; Met_dep_hydrolase_A; 1.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   Gene3D; 3.90.850.10; Fumarylacetoacetase-like, C-terminal domain; 1.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   Gene3D; 2.30.40.10; Urease, subunit C, domain 1; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   InterPro; IPR006680; Amidohydro-rel.
DR   InterPro; IPR011234; Fumarylacetoacetase-like_C.
DR   InterPro; IPR036663; Fumarylacetoacetase_C_sf.
DR   InterPro; IPR011059; Metal-dep_hydrolase_composite.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   PANTHER; PTHR11820; ACYLPYRUVASE; 1.
DR   PANTHER; PTHR11820:SF115; FUMARYLACETOACETATE HYDROLASE; 1.
DR   Pfam; PF00561; Abhydrolase_1; 1.
DR   Pfam; PF01979; Amidohydro_1; 1.
DR   Pfam; PF01557; FAA_hydrolase; 1.
DR   PRINTS; PR00111; ABHYDROLASE.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   SUPFAM; SSF51338; Composite domain of metallo-dependent hydrolases; 1.
DR   SUPFAM; SSF56529; FAH; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053599}.
FT   DOMAIN          107..452
FT                   /note="Amidohydrolase-related"
FT                   /evidence="ECO:0000259|Pfam:PF01979"
FT   DOMAIN          548..760
FT                   /note="Fumarylacetoacetase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01557"
FT   DOMAIN          809..1041
FT                   /note="AB hydrolase-1"
FT                   /evidence="ECO:0000259|Pfam:PF00561"
SQ   SEQUENCE   1053 AA;  114390 MW;  3B0F8E3DC8D5D026 CRC64;
     MAPGILTNGW NGDVQVRSKG SRKSYAYESL RFDSKLQPRK YEIAGTPQSS KVLFLDVNIL
     DSTGDEPYRG DVYIEGDRIV AVGKVPNVDR LRRSTDVKVI NGRGRTLMSG LGDAHAHFTW
     NDNALELLGD VGVEEHTLIT IKSAKCYIDS GYTMAYGAAS AKDRLDVVIR DAINNGDIPG
     PRLLANGREI ARRDGELAAG ITAFADAGPL EMRELIRHHA KLGVDQIKLS MSGEAITELR
     SAEDCFFTDE ETAACVDEAH RHGLRVCSHA RARDSVIQCV EHGVDVIYHA SYTDSIGMDM
     LEKAKHKHVV APAINWLYTT VHEAVSFGYS HEKAEQVGYT RELEIATQAL KEMHKRGITV
     LPGGDYGFAW CPHGTYARDL EHFVKLLDFT PMESIIAATA GIAKLFMQEN ELGKIQPGFY
     ADCILVDGDP LKDIAVLQDH DKLNVIMING RLHKSSASDF AQLETAIPTP VQAKAHYNFV
     TFEDSLGRPR VGHLDFETST VYNLTMSSGS HLSSLRQVIE LDNDVVRTEE SFSLATTNLL
     APIHDRDILC VGSNYSDHAK EFRESGYDRT GLQQKANFPT IFTKRKGSVI GSNEDIYAHP
     GFTESLDYEG EVGVIIGKPG FSISEANAMD HVWGYTIIND VTAREKQRDH GQFLMGKSAD
     TFCPMGPVAV PASALPSTLR VQTYVNGEKR QDGSTDMLIT SIPKLIEIIS AGMTLEPGDV
     IATGTPAGVG VGMKPEPKFL KAGDLVEISI TGLGTLSNRV SDKTPETPMT KPVSSLPQYN
     LERSWGGAGL TRVGDKLVNV RELGSGPQTV VFIHGLGSSM EYYMPLLQTM NLKDRYRVIL
     YDFEGHGLTP TTAAATTTIE SLVEDLENLF VTKDIGRAVV VGWSIGGLVA MLFAQHNPSA
     VEKLVLLGPG PNPFPEPAVE VFSKRAAAVR AQGMDASGVA GAVVAAATSA KTQSERPVAV
     SAVRQSLLAT HPEGYAKGCL ALAKSRNTTV KVEELKMPVL VVAGTDDKIS PMSLCEGYVK
     RLPDARLKVV EGVGHWHVLE DVHGVARAME GFM
//