ID A0A0D1YPG7_9EURO Unreviewed; 777 AA.
AC A0A0D1YPG7;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=cellulase {ECO:0000256|ARBA:ARBA00012601};
DE EC=3.2.1.4 {ECO:0000256|ARBA:ARBA00012601};
GN ORFNames=PV11_00493 {ECO:0000313|EMBL:KIV84727.1};
OS Exophiala sideris.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=1016849 {ECO:0000313|EMBL:KIV84727.1, ECO:0000313|Proteomes:UP000053599};
RN [1] {ECO:0000313|EMBL:KIV84727.1, ECO:0000313|Proteomes:UP000053599}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 121828 {ECO:0000313|EMBL:KIV84727.1,
RC ECO:0000313|Proteomes:UP000053599};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala sideris CBS121828.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Endohydrolysis of (1->4)-beta-D-glucosidic linkages in
CC cellulose, lichenin and cereal beta-D-glucans.; EC=3.2.1.4;
CC Evidence={ECO:0000256|ARBA:ARBA00000966};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 9 (cellulase E) family.
CC {ECO:0000256|ARBA:ARBA00007072}.
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DR EMBL; KN846951; KIV84727.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D1YPG7; -.
DR STRING; 1016849.A0A0D1YPG7; -.
DR HOGENOM; CLU_006010_0_0_1; -.
DR OrthoDB; 2100839at2759; -.
DR Proteomes; UP000053599; Unassembled WGS sequence.
DR GO; GO:0008810; F:cellulase activity; IEA:UniProtKB-EC.
DR GO; GO:0030245; P:cellulose catabolic process; IEA:UniProtKB-KW.
DR CDD; cd02850; E_set_Cellulase_N; 1.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR004197; Cellulase_Ig-like.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR001701; Glyco_hydro_9.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR22298; ENDO-1,4-BETA-GLUCANASE; 1.
DR PANTHER; PTHR22298:SF29; ENDOGLUCANASE; 1.
DR Pfam; PF02927; CelD_N; 1.
DR Pfam; PF00759; Glyco_hydro_9; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Cellulose degradation {ECO:0000256|ARBA:ARBA00023001};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326};
KW Reference proteome {ECO:0000313|Proteomes:UP000053599};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..777
FT /note="cellulase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002237229"
FT DOMAIN 189..270
FT /note="Cellulase Ig-like"
FT /evidence="ECO:0000259|Pfam:PF02927"
FT DOMAIN 281..770
FT /note="Glycoside hydrolase family 9"
FT /evidence="ECO:0000259|Pfam:PF00759"
FT REGION 451..470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 715..735
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 777 AA; 83038 MW; 75A758971F03AEAA CRC64;
MAAFLTAVAT TASLLSIFTS LVNARSAPVQ ARDVTLPPIP GSPQIITNGA FTNATYGWES
SPTGKIQNGL YCITVPSGSA PGNSSYLRTT YQFLETKNDV YTVNFTASSS VGFDINVQTP
DPPLDPNLNT TAPLTTTPHP FSFTFSPANQ APNATLEFDL GGAPAEAQVC IGDVSMKRID
RSGYVQFVGP ALKVNQLGYL PQGPKLATLV ANDTQAVTWS LLSSSGNTVA SGKTTPKGMD
AASGQVVSTI DFSNVTQEGY GYVLTTGNAS SYPFTISSTV YDTLRQDSLL FFYQQRSGIA
IDAALAGSQY ARAAGHVQVP PNQGDVQVPC QAVHDSMIAY LEPWTCNYTL NVTQGWYDAG
DQGKYVVNGG ISAAQLLMEY ERTLHIANAT NALVDGSLRI PERNNGIPDI LDEARWEIDF
LLKMQVPSGS PPQLFNGSMI DMSGLAHHKM HDNQWTPLPT DPSQDPKRRE LHRPSTAATL
NLAAVGAMAA RSFAKYDSAF SQQCLQAATT AYTAAKKNPA ILAPSTDWDL GGGAYNDDDV
TDEFYWAAAE LYLTTGQQQY LTDLTNNTYH TANVSTLFSI PGGFSWGSVA ALAQLDLATI
PSNISNHSAI VQSVLAAADM YLAVQRNSSN GYGVFLNSYP WGSNSNNLNN VQVVATAYDL
SGNTTYRDAA LQGIDYVLGR NALAFSYIRN YGTNYVQNVH SRLYAHELND QVPQAPAGAM
SGGANEDASD PPADDVLQGC KPQLCHVDDV NSYSTNEVAI NWGSALAWVV GWAASQA
//
