ID A0A0D1YVA3_9EURO Unreviewed; 750 AA.
AC A0A0D1YVA3;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Choline kinase N-terminal domain-containing protein {ECO:0000259|Pfam:PF04428};
GN ORFNames=PV08_03510 {ECO:0000313|EMBL:KIW19216.1};
OS Exophiala spinifera.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=91928 {ECO:0000313|EMBL:KIW19216.1, ECO:0000313|Proteomes:UP000053328};
RN [1] {ECO:0000313|EMBL:KIW19216.1, ECO:0000313|Proteomes:UP000053328}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 89968 {ECO:0000313|EMBL:KIW19216.1,
RC ECO:0000313|Proteomes:UP000053328};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala spinifera CBS89968.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- PATHWAY: Phospholipid metabolism. {ECO:0000256|ARBA:ARBA00025707}.
CC -!- SIMILARITY: Belongs to the choline/ethanolamine kinase family.
CC {ECO:0000256|ARBA:ARBA00038211}.
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DR EMBL; KN847493; KIW19216.1; -; Genomic_DNA.
DR RefSeq; XP_016239432.1; XM_016377862.1.
DR AlphaFoldDB; A0A0D1YVA3; -.
DR STRING; 91928.A0A0D1YVA3; -.
DR GeneID; 27330593; -.
DR VEuPathDB; FungiDB:PV08_03510; -.
DR HOGENOM; CLU_012712_4_0_1; -.
DR OrthoDB; 144299at2759; -.
DR Proteomes; UP000053328; Unassembled WGS sequence.
DR GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
DR CDD; cd05157; ETNK_euk; 1.
DR Gene3D; 3.90.1200.10; -; 1.
DR InterPro; IPR007521; Choline_kin_N.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR22603; CHOLINE/ETHANOALAMINE KINASE; 1.
DR PANTHER; PTHR22603:SF93; RE24176P; 1.
DR Pfam; PF04428; Choline_kin_N; 1.
DR Pfam; PF01633; Choline_kinase; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000053328}.
FT DOMAIN 153..221
FT /note="Choline kinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04428"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 59..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 124..150
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 246..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 573..600
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 640..706
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 62..78
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..101
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 254..273
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 660..699
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 750 AA; 85412 MW; AC95134FF5B3F555 CRC64;
MTGRPSLNTA GSSTTSLSHP MSYLSLDKAE GESAGTPNDA KAPDLRAMLN QVVDWLQEEK
SKRQKRKHHR HHLIHHRSHL TPNLPEGNQS DDSAQDAESS QSLAKLESIL SGFTSWSTAI
PKWSSRASSA PSRKGSIARK FKRASVGPQS SDTEFFGDDI LVPNVEAHLD NSKTLAFTGG
GVDVDTSDAA KKRDYEHWVT FKEDILRLTH TLKIKGWRRV PMERAKDIDV VRLSGALTNA
VYVVRPPKNM PEPAPSSNSQ TATSETASAS TSSQPRKAVQ LLLRIYGPQV EHLIDREAEL
SILRRLCRKR IGPRLLGTFE NGRFEEFLHA KTLTAEDLRI PETSKQIAKR MRELHDGIEL
LESELEAGPA VFVNWDKWVD RCEKVITWLD SQIHQAERER QAGVSRQDSA IEQRYIRNGL
ICGVEWPLFR RTYEAYRQRL IEESGGVKKI RDGLVFAHND TQYGNLMRLQ PSGTSPLLQP
SNQHKQLVVI DFEYASQNMP GLEFANHFTE WSYNYHHPEH SWMCDTRRYP NESEQYRFVR
SYTMHRPQFN PSASSTPKLE AREKTNISDF MLDARAPPGT SVSGQSLETD YDAEEKEREK
AQEEEIQRYL RETRIWRPAN SAQWVAWGIV QAKVPELEAL ENGNEREEPG NVVPMSDPLN
EEEKQLKEES EADRPEGRAQ EESHHEGDVK MGEQNGAEDE GGGEEHEEFD YLAYAQDRAM
FFWGDCVQMG LVKLEELPEE MRTRVKIVPY
//
