ID A0A0D2AVS8_9PEZI Unreviewed; 1917 AA.
AC A0A0D2AVS8;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 13-SEP-2023, entry version 36.
DE RecName: Full=DH domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PV09_05488 {ECO:0000313|EMBL:KIW03269.1};
OS Verruconis gallopava.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Venturiales; Sympoventuriaceae; Verruconis.
OX NCBI_TaxID=253628 {ECO:0000313|EMBL:KIW03269.1, ECO:0000313|Proteomes:UP000053259};
RN [1] {ECO:0000313|EMBL:KIW03269.1, ECO:0000313|Proteomes:UP000053259}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 43764 {ECO:0000313|EMBL:KIW03269.1,
RC ECO:0000313|Proteomes:UP000053259};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Ochroconis gallopava CBS43764.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KN847545; KIW03269.1; -; Genomic_DNA.
DR RefSeq; XP_016213138.1; XM_016358999.1.
DR STRING; 253628.A0A0D2AVS8; -.
DR GeneID; 27313461; -.
DR VEuPathDB; FungiDB:PV09_05488; -.
DR HOGENOM; CLU_001112_0_0_1; -.
DR InParanoid; A0A0D2AVS8; -.
DR OrthoDB; 25601at2759; -.
DR Proteomes; UP000053259; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd07589; BAR_DNMBP; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR PANTHER; PTHR22834; NUCLEAR FUSION PROTEIN FUS2; 1.
DR PANTHER; PTHR22834:SF20; NUCLEAR FUSION PROTEIN FUS2; 1.
DR Pfam; PF03114; BAR; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR PROSITE; PS51021; BAR; 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000053259}.
FT DOMAIN 1145..1368
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 1402..1620
FT /note="BAR"
FT /evidence="ECO:0000259|PROSITE:PS51021"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 46..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 320..484
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 586..663
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 719..739
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 880..914
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 993..1088
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1114..1137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1224..1250
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1658..1704
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1726..1798
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1824..1843
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1351..1378
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 53..68
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 128..178
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 201..247
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 320..385
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 398..438
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 468..482
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 586..605
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 618..663
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 719..734
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 891..905
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 993..1016
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1017..1042
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1225..1246
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1671..1704
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1726..1750
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1779..1793
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1917 AA; 209910 MW; 05B46F583377FF80 CRC64;
MSNADPFSAS NSSSHATTTT FTTTTVTTTT AANGLSASFE YDPYSSENYY RVNPTPLPPP
PPPPQPEQYQ HRFSTSAASL EGDPDDFYRP FADHRASHPD IVIQTVPDDA EPRPGMMPNP
TARQRRASAA GGISSSRLPI ATASANSSPS RPSTRSASGP VATARPTGLS SAKSMGALGA
SSHIQGHGGT IRERVQQLER SRESSPAAEG SRGASSTGRY YSRSRPPSSA SANVTTANTS
TPASVGALRS PPRTRLSKDH MPASSPLDLH TDGRGRRLLF GEVDTSMAAA TNLVGHGIDV
VHAAHTTSTS GSMHEPNAMF ARSRSQSDVS SSNSPTLGHT GTGHSRSYSH EASLQPYSAS
SSNVSSSTPS PTGDHSRNLS PSASRIPVPR SRRASDIGPA NGSASRSRSR PNAQTTPAYS
QQQATVAASS SSPMLLSSRR YSPPRKLADP SHLHAMVKAP PPKTSPPLRS TRNRQPVTAA
TVASKAKVTE RFKPMQNSSS STRLQKPTIP QVDIAERRAR LQKNLAGGDT RARPVRQDLK
NLQEGKYPSR RTNWVEADAA SDVSSDTLPS RKSLTTMSVP LLSIETSDVG GNASGTQQSD
VRSAGGASTD FEESPTAGVD EGQQQHQAVP IQVTPPTESA ELEPATKSSA PATSPEHLQN
RRDSQSLLKH VLSLRQHSPS ETSPVSRTEV PDDYLTQIDD GETVQFMLGT TPKLAAQTWT
PELPTNNSGS SPEAFHTPRE EGGSDFDDGF DGFDGRSSIV PDDSVSMVFQ RKYAEMLARE
QPPPPMPDNA VEIARSYHFD RTNADNGNND KINNHNTYTL STEARSEINR VLDQYQEGHV
TPEMAHGFRQ QVEALTPNLS RHDAWDSPEA TKRYLRSVLQ ESVMTESTPN AREEDAARTG
GPEEPTEESE AGGGIAIIYG PVRNDELGEP LERTGTLHSH STSNATLRPA KDEIDDEKHR
SYLEDIAFRP APPPKDFIDF DGGSDPARIT SIPTLPEFSS PASGLGLSMT PPESGPVSTS
THPPAPTHAP PPLPPAPPTP QKDIFIPHAT QPAVSSAPPS GPGYDAFIPG LPSSPAAARG
RPAPQTQQQV MAEAINQDVP RSTGASIDTV VTSRNQSPFS IARSTNGDRS SQSLTTPDIE
KDLTQRRHRV KELVDTEHTF HQDLTVMTDI YLATAAEVIG EDDRRILFGN IEQLRNFTTD
FLDDLKRAAA PIYVIPRENR WNHKRGSFTT SNSETTENSS SSSVTTEERI ENDRCTTIGQ
TFCEHLPTLQ KVYSEWLRNA NAANKRLIEL QKQPAVKYWL DECIESHKDL TSAWNLDSLI
VKPFQRSAKY TLLLDEILRF TPPDHPDYAM LKQAKDLVKA YNERANDIQK RSELVEQAMS
KHKDPNGRIK VSKLLNRRTE KLKQQVGLSG LAEDPEYDAI AQKFGGHFFQ LQVVMRDVEK
YLEDVQHYVD QYVLLMEALV GNIGLDALNR YPEMESRWIA FRTAIVEMKN VALGDHTRKV
RRTVIDPIQQ LWRLHVGPQK MMAKRKKRIV EFVRHRNMLE KGEKPDKRLE QEAEQFRAVN
ETLKEELPRL YALTKKLVEN CLLNFIELQS QWQRDWTRKL SPLIDDMEPL LGVELDQALF
SVQTAYAQDI TEAQDVLATF KVCNKMLVTE ARNFKSPATT YSRDDESYAK RPSTLGSSAG
GKRAASMSNE HVGHSTPNLR LSGDNITLSP LVGALGMPEA VYQTTNNHQQ RNRAGSAMSS
RGSSTPYSAA GYIGPTAYGY SRPTTSDRGE PSPGVVPRLS LDSPTTRSPA RNEFGGNTYV
VPDARLPASA PLQMDDRFSG MFHSALPMSD SPRAPSPEQD HGTHEPHVLF LAASLFEFYI
DSTRTEGGYP YLTYQPGEIF DVVAQKGELW LAKNQDDPTN TIGWIWEKHF ARILPDN
//
