ID A0A0D2C3E1_9EURO Unreviewed; 1381 AA.
AC A0A0D2C3E1;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 28-JUN-2023, entry version 27.
DE RecName: Full=BRCT domain-containing protein {ECO:0000259|PROSITE:PS50172};
GN ORFNames=PV06_05316 {ECO:0000313|EMBL:KIW44297.1};
OS Exophiala oligosperma.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=215243 {ECO:0000313|EMBL:KIW44297.1, ECO:0000313|Proteomes:UP000053342};
RN [1] {ECO:0000313|EMBL:KIW44297.1, ECO:0000313|Proteomes:UP000053342}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 72588 {ECO:0000313|EMBL:KIW44297.1,
RC ECO:0000313|Proteomes:UP000053342};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala oligosperma CBS72588.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KN847335; KIW44297.1; -; Genomic_DNA.
DR RefSeq; XP_016264513.1; XM_016406307.1.
DR STRING; 215243.A0A0D2C3E1; -.
DR GeneID; 27357390; -.
DR VEuPathDB; FungiDB:PV06_05316; -.
DR HOGENOM; CLU_002263_0_0_1; -.
DR OrthoDB; 1406366at2759; -.
DR Proteomes; UP000053342; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006974; P:DNA damage response; IEA:UniProtKB-KW.
DR CDD; cd17745; BRCT_p53bp1_rpt1; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR047249; BRCT_p53bp1-like_rpt1.
DR InterPro; IPR041297; Crb2_Tudor.
DR InterPro; IPR047252; TP53BP1-like.
DR PANTHER; PTHR15321:SF3; TP53-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR15321; TUMOR SUPPRESSOR P53-BINDING PROTEIN 1; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF18115; Tudor_3; 1.
DR SMART; SM00292; BRCT; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR PROSITE; PS50172; BRCT; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000053342}.
FT DOMAIN 1091..1197
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 54..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 105..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 264..354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 374..444
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 504..870
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1056..1075
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1327..1354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..146
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 147..174
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 194..214
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 264..280
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 374..426
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 515..550
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 585..647
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 654..672
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 722..736
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 759..783
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 800..814
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 830..859
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1381 AA; 151316 MW; C42337A2D776CD0D CRC64;
MEAAPILLDS ESESLDVSSI KFAVLHDQES IQDQPGSDRR LVPQRQLEAI RHALDGLSPI
EPSPIEPSPI ITTPATNTVP ELASIVPESE SLPNVESPFT FLRPAITHER RATPVQKMTS
QGSDAPTQEL SQSHYTSFLQ SRSRSAAQLL REHHEEDDEE SPQFSLREGD EGHIDLLSSL
VSPKNGPSEL DSEPVEYSPT QTQLALSRFP ESQRFKTPAT AGKKRSYDGD IIDSPVLPRN
PLLGGGSHQQ ENIMGLSQAF AATQADTSPF VNNGNGDIPS DRPSPNIELR PRPVTATSSP
MRPISAFKRA STEPASRYIS VREELALREH AGPEPQEASD DEEDDVFAHL QEPDSMTKYR
RRLAIEKQVK VSLQRLSSPS TRLLRRPSLS KSSPVRQNRR SSPIEPLSSR ITRFTDRSSP
TKADSPDPLQ ESEEETDLED SPQIAVARSS QVMVALNDGD DDKENCLSNG SQVPETAARL
IRVAHGDPSE VEDSPSLRHH RRISAEKHAM HSSQPFAIAD SQSSQSRRRM QKLSQALKST
PGTGSVDFVP QSPTAGIEVT DASEKERTTA NDVPDGLSED VPNAMPENAA SNSPVHQKGT
IPETSSNEPP TEPSRGDAST KQSDPDTTSR GEFETAQSQV PQSIEHSKQQ ENGEDIGTGD
SNGHSTPSCN RRRMTEIAAE PSPLKSQPSF NVTDALHLDA AFQSPSKRPP LNNPSVSRFT
EHIHVPPEEQ ENTEHVEGPE NASNYGHPVE RNNEMKQRRN QNLHGNSLDL ASTTPQTTIH
SSRRLRKPTP KALENSKPHT PLADAQSRRS QWDLDASPPQ KAPLTRPNSS LKRKKREQLS
PADAQETSAK RRKVPEKATT ASSRHTPIAD ECEDISAQHL ENLGTALNTV VEQVSENPSV
PNVVFACFNG KTRAYYPATC LGLSDADPTR YRIQWEGYDP EELDQHGVRS LDLRVGDQIK
VNLQGFPKVP YIIKAFKNRI SAHAPKSEDQ ILTDIQGYKT LLVSTKQRKS LPADVSTEAL
KEVPISSIYL DSNMWGQMKD RLYEHKTTVP RPMVSAMSTP APCSSTPCSP PSRNRRGTTA
VTTALSLSTC VVEGLFTNMA FAISYDDDTR RDQLERQIRQ QGGLVLKESF LDLLELDSLQ
MKAQHADLSF TALLADRQSR KEKYMQALAL GVPCLSGRWI ESCVHAEELV TWSTYLLPSG
ECAELEGATR SRVLSFDPAA NLKVHEMIES RARILNGARV VVAMKSGGEK VEKRRRAFVF
LIRALGAGEI VSVSDLASAT AEVRGTGDSS DDEDTFVFVD DRDIGSAKTL FEESAAVRIS
RKAGKKTRTL GKANKTGAGS DGGGGREGAD PGGEGKIHSN VKVICNEDVV QSLILGRLWI
G
//
