ID A0A0D2CU00_9EURO Unreviewed; 637 AA.
AC A0A0D2CU00;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 22-FEB-2023, entry version 36.
DE RecName: Full=Nucleolar protein 58 {ECO:0000256|ARBA:ARBA00020379};
GN ORFNames=PV05_09066 {ECO:0000313|EMBL:KIW53497.1};
OS Exophiala xenobiotica.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=348802 {ECO:0000313|EMBL:KIW53497.1, ECO:0000313|Proteomes:UP000054342};
RN [1] {ECO:0000313|EMBL:KIW53497.1, ECO:0000313|Proteomes:UP000054342}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 118157 {ECO:0000313|EMBL:KIW53497.1,
RC ECO:0000313|Proteomes:UP000054342};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala xenobiotica CBS118157.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for pre-18S rRNA processing. May bind microtubules.
CC {ECO:0000256|ARBA:ARBA00024837}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the NOP5/NOP56 family.
CC {ECO:0000256|ARBA:ARBA00009211}.
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DR EMBL; KN847321; KIW53497.1; -; Genomic_DNA.
DR RefSeq; XP_013314081.1; XM_013458627.1.
DR AlphaFoldDB; A0A0D2CU00; -.
DR STRING; 348802.A0A0D2CU00; -.
DR GeneID; 25330974; -.
DR HOGENOM; CLU_015495_5_0_1; -.
DR OrthoDB; 5489581at2759; -.
DR Proteomes; UP000054342; Unassembled WGS sequence.
DR GO; GO:0031428; C:box C/D RNP complex; IEA:InterPro.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0032040; C:small-subunit processome; IEA:InterPro.
DR GO; GO:0030515; F:snoRNA binding; IEA:InterPro.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.10.287.4070; -; 1.
DR Gene3D; 1.10.246.90; Nop domain; 1.
DR InterPro; IPR045056; Nop56/Nop58.
DR InterPro; IPR012974; NOP58/56_N.
DR InterPro; IPR042239; Nop_C.
DR InterPro; IPR002687; Nop_dom.
DR InterPro; IPR036070; Nop_dom_sf.
DR InterPro; IPR012976; NOSIC.
DR PANTHER; PTHR10894; NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58; 1.
DR PANTHER; PTHR10894:SF1; NUCLEOLAR PROTEIN 58; 1.
DR Pfam; PF01798; Nop; 1.
DR Pfam; PF08156; NOP5NT; 1.
DR SMART; SM00931; NOSIC; 1.
DR SUPFAM; SSF89124; Nop domain; 1.
DR PROSITE; PS51358; NOP; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000054342};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552}.
FT DOMAIN 285..413
FT /note="Nop"
FT /evidence="ECO:0000259|PROSITE:PS51358"
FT REGION 416..549
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 575..637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 437..477
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 478..498
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 515..549
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 575..598
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 609..630
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 637 AA; 69591 MW; 162B37332FA5600B CRC64;
MTLLILTETA AGYALLKAKD KKLLKRDDLA SELEGVENVT SALKLKEFQK FDSAAAALEE
AAAIVEGKVT PKLSSLLDTL KDEKKISLAV ADPKLGNAIG KLPGLDIKAI ADSATADLYR
AIREHLPSLI PGLMPDDVKT MSLGLSHSLA RHKLKFSPDK IDVMIVQAIG LLDDLDKELN
TYAMRVKEWY GWHFPEMAKI LNDNLAYAKV VLKMGMRTNW ENCDLAEILP EEIEAAVKAA
ADRSMGTEIT EEDLENIQSL AEQVVQFTEY RTQLASYLSA RMTAIAPNLT TLVGELVGAR
LIAHAGSLLN LSKSPASTLQ ILGAEKALFR ALKTKHDTPK YGLIYHASLI GQASGKNKGK
MARILAAKAA LGLRVDALQE WGEDEANIPE DEKAQLGIEA RANLERKLAA MEGKPLKPRG
VAIGPNGVPG TTQPQKWEIK EARKYNPDAD GLAGDEAPAK QEKKSKKDKK LVQEIPEDTI
MEDGEVDDEE DESQPDEPID AAEAAAINGV NGEKSAKKAV KERRRAEKAA RKTAKKEKKE
GKAETTDETK IETLAALCGL SVERYKRKLE RGEIEFTEDG KPVSISKKDI KKAKKASEKA
AAASANGEVD GSKKRKRVEE EIEPVKSEKK KKRKEKA
//
