ID A0A0D2CUV6_9EURO Unreviewed; 699 AA.
AC A0A0D2CUV6;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Acetoacetate-CoA ligase {ECO:0000313|EMBL:KIW53887.1};
GN ORFNames=PV05_06296 {ECO:0000313|EMBL:KIW53887.1};
OS Exophiala xenobiotica.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=348802 {ECO:0000313|EMBL:KIW53887.1, ECO:0000313|Proteomes:UP000054342};
RN [1] {ECO:0000313|EMBL:KIW53887.1, ECO:0000313|Proteomes:UP000054342}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 118157 {ECO:0000313|EMBL:KIW53887.1,
RC ECO:0000313|Proteomes:UP000054342};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala xenobiotica CBS118157.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KN847320; KIW53887.1; -; Genomic_DNA.
DR RefSeq; XP_013314471.1; XM_013459017.1.
DR AlphaFoldDB; A0A0D2CUV6; -.
DR STRING; 348802.A0A0D2CUV6; -.
DR GeneID; 25328204; -.
DR HOGENOM; CLU_000022_3_3_1; -.
DR OrthoDB; 45466at2759; -.
DR Proteomes; UP000054342; Unassembled WGS sequence.
DR GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR005914; Acac_CoA_synth.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR PANTHER; PTHR42921:SF4; ACETOACETYL-COA SYNTHASE (AFU_ORTHOLOGUE AFUA_8G04770); 1.
DR PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:KIW53887.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054342}.
FT DOMAIN 40..98
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 113..500
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
SQ SEQUENCE 699 AA; 77778 MW; E4C0E198D19757BF CRC64;
MVEEHPIPRK LWVHPDPQST EMYKFKTRLQ KKLGRTFESY DDMYDWSCSN RSDFWKFVLE
CFPVVYSGTV PDKVVDESAR MDSIPRWFPG VKMNFAQNIL FSGDANGKPV IDAAKADDKV
ACTQVREGSF LEPIRYFTWK ELRQRVGRLS QAMKAQGVSK GDRIAIVAST SIDTLTVFLA
TTTLGALFSS SSTDMGVKGI LDRLTQIKPK YLFMDDWAVY NGKKVDLKPK MKDIMAGMDG
ITEFQGIVTQ ARFDHSPADV SSVPRAQTWS NFLSAAKSSV LEFEPTNFSD PFLVVYSSGT
TGQPKCIVHA IGGVVLNGHK EAGLHCQLGP ESTQLQYTTT GWIMYMASVQ ALLRGCRMLM
YDGSPFVPNI TNFVKLLGQE KVTHLGISPR YMQTLQANKI APKEVTDLSN LKLVTSTGMV
LSEQLFEWFY DQGFPPSAQL ANISGGTDLV GCFGCGNPIL PVYSGGCQSR SLGIPVKVCD
QTIEGGKAVE VEDGVPGELI SYAAFPTMPI TFLGTNGPKR YFDSYFARFD NVWTHGDFIM
IHSVTKQVMF LGRSDGVLNP SGVRFGSAEI YNILESKFAD KISDSICVGQ RRPTDDDERV
VLFLLMKPGH EFTPKLIREV KEAIRKETSP RHVPKFVFET KDIPTTVNLK KVELPVKQIV
SGKVIKASGT LANPESLDYY YRFAKDENLV DLADPKAKL
//
