ID A0A0D2EGQ9_9EURO Unreviewed; 592 AA.
AC A0A0D2EGQ9;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Magnesium transporter {ECO:0000256|RuleBase:RU366042};
GN ORFNames=PV06_02743 {ECO:0000313|EMBL:KIW47144.1};
OS Exophiala oligosperma.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=215243 {ECO:0000313|EMBL:KIW47144.1, ECO:0000313|Proteomes:UP000053342};
RN [1] {ECO:0000313|EMBL:KIW47144.1, ECO:0000313|Proteomes:UP000053342}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 72588 {ECO:0000313|EMBL:KIW47144.1,
RC ECO:0000313|Proteomes:UP000053342};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala oligosperma CBS72588.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC inner membrane {ECO:0000256|RuleBase:RU366042}; Multi-pass membrane
CC protein {ECO:0000256|RuleBase:RU366042}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC family. {ECO:0000256|ARBA:ARBA00009765, ECO:0000256|RuleBase:RU366042}.
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DR EMBL; KN847333; KIW47144.1; -; Genomic_DNA.
DR RefSeq; XP_016267360.1; XM_016403463.1.
DR AlphaFoldDB; A0A0D2EGQ9; -.
DR STRING; 215243.A0A0D2EGQ9; -.
DR GeneID; 27354817; -.
DR VEuPathDB; FungiDB:PV06_02743; -.
DR HOGENOM; CLU_025144_2_1_1; -.
DR OrthoDB; 73031at2759; -.
DR Proteomes; UP000053342; Unassembled WGS sequence.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015693; P:magnesium ion transport; IEA:UniProt.
DR CDD; cd12823; Mrs2_Mfm1p-like; 1.
DR Gene3D; 2.40.128.330; -; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 1.
DR InterPro; IPR045863; CorA_TM1_TM2.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR InterPro; IPR039204; MRS2-like.
DR PANTHER; PTHR13890:SF26; MAGNESIUM TRANSPORTER MRS2 HOMOLOG, MITOCHONDRIAL; 1.
DR PANTHER; PTHR13890; RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL; 1.
DR Pfam; PF01544; CorA; 1.
DR SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|RuleBase:RU366042};
KW Magnesium {ECO:0000256|RuleBase:RU366042};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU366042};
KW Mitochondrion {ECO:0000256|RuleBase:RU366042};
KW Mitochondrion inner membrane {ECO:0000256|RuleBase:RU366042};
KW Reference proteome {ECO:0000313|Proteomes:UP000053342};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU366042};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU366042};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU366042}.
FT TRANSMEM 402..420
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366042"
FT TRANSMEM 432..453
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366042"
FT REGION 26..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 66..87
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 526..592
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 536..552
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 553..583
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 592 AA; 66152 MW; 2CC8FC236B370BF3 CRC64;
MKTPWAPSRD LLRFLRTQAN SVFITPVAPT RPPHSRALST SSSRCSRLQT SSVDDIWQRQ
RDPCKALPAP RCAPPGPLQS RNASSGSHSP GFWLRWFRRR QAAVRSKLPP DPPGNSSNYD
ETSAQLFNLS RALSRNQTGA DLKLRCTEFD ANGSVTMVAG EFRKSELIAK YGLLPRDLRK
IDSSVLPHIL VRPTAILINL LHLRVLIQSD RVLVFDAYGS TDSYTQSLFM YDLEGKLRQK
ADPRNGSTYL PYEFRALEAV LISVTSGLEA EFALVRDPVV HILRELEEDI DRDKLRHLLI
HSKKLGTFEQ KARLVRDAID DLLEADDDLS AMYLTERKAS KTSRPEHDHQ EVEMLLESYH
KICDEIVEIS GNLINNIRNT EEVVKAILDA NRNQLMLLEI KFSVGTLGLA GGTLIAGLYG
MNLNNFIEET DWGFGTVSVV CFALSAVICV YGMRKLRKVQ KVRMWGEGLD TMGHRARIGS
RGNWHNEAFE SQAHRAGRLK GGGINLGGKQ SGPVYWPGME GLGAHRLHAT GTNPFGSGDA
ADTTGTSHEP QMTIQDDVED VEAKWREDSK KQKGLMTKDH HHPTTHHTPG KK
//
