ID A0A0D2EJS1_9EURO Unreviewed; 756 AA.
AC A0A0D2EJS1;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=Protein SDA1 {ECO:0000256|RuleBase:RU365057};
GN ORFNames=PV05_04404 {ECO:0000313|EMBL:KIW55673.1};
OS Exophiala xenobiotica.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=348802 {ECO:0000313|EMBL:KIW55673.1, ECO:0000313|Proteomes:UP000054342};
RN [1] {ECO:0000313|EMBL:KIW55673.1, ECO:0000313|Proteomes:UP000054342}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 118157 {ECO:0000313|EMBL:KIW55673.1,
RC ECO:0000313|Proteomes:UP000054342};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala xenobiotica CBS118157.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for 60S pre-ribosomal subunits export to the
CC cytoplasm. {ECO:0000256|RuleBase:RU365057}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|RuleBase:RU365057}.
CC -!- SIMILARITY: Belongs to the SDA1 family. {ECO:0000256|ARBA:ARBA00005783,
CC ECO:0000256|RuleBase:RU365057}.
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DR EMBL; KN847319; KIW55673.1; -; Genomic_DNA.
DR RefSeq; XP_013316257.1; XM_013460803.1.
DR AlphaFoldDB; A0A0D2EJS1; -.
DR STRING; 348802.A0A0D2EJS1; -.
DR GeneID; 25326312; -.
DR HOGENOM; CLU_009161_2_1_1; -.
DR OrthoDB; 5482564at2759; -.
DR Proteomes; UP000054342; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:UniProtKB-UniRule.
DR GO; GO:0000055; P:ribosomal large subunit export from nucleus; IEA:UniProtKB-UniRule.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR027312; Sda1.
DR InterPro; IPR048292; SDA1_C.
DR InterPro; IPR007949; SDA1_MD.
DR InterPro; IPR012977; SDA1_N.
DR PANTHER; PTHR12730; HSDA/SDA1-RELATED; 1.
DR PANTHER; PTHR12730:SF0; PROTEIN SDA1 HOMOLOG; 1.
DR Pfam; PF21638; SDA1_C; 1.
DR Pfam; PF05285; SDA1_dom; 1.
DR Pfam; PF08158; SDA1_HEAT; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU365057};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|RuleBase:RU365057};
KW Reference proteome {ECO:0000313|Proteomes:UP000054342};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517,
KW ECO:0000256|RuleBase:RU365057};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365057}.
FT DOMAIN 70..437
FT /note="SDA1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08158"
FT DOMAIN 546..679
FT /note="SDA1 middle"
FT /evidence="ECO:0000259|Pfam:PF05285"
FT DOMAIN 703..748
FT /note="SDA1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21638"
FT REGION 509..605
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 623..652
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 676..756
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 517..559
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 560..599
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 623..641
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 676..716
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 728..756
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 756 AA; 85076 MW; 1F25FB9C8F0165AC CRC64;
MVKRKLGALE KVDADLANLQ NKIKRDPRSY HTDFSHQYIQ YENQRQIFMQ SPSSSSDTNS
VISFRDLIEF VAHVADCYKE ETKEFPSQLI EILSAHHASL EPELREKIVG SLVLLRKKEI
IDSTTLLQCF FPILVSTPSK SLRALLFQKI ISDLRSSNAK TTNHKLNRSV QTTLHNLVVA
DRASPKALWA VKITREMWKR QIWTDAKAVE IMKEAAVGDN EKCIVGGVRF FLGGDKEREE
LEDESSDDEG IDMAKLRHQV GVNKSKKAER RLEKAAATVK RKQKKKGQPH PLNFSALHLL
HDPQGFAETL FTKHLQAAKS KLNLEQKLAV LQLVSRLIGL HKLTVISFYS YFLKYLTPRQ
PSVTSFLASL AQATHNLVPP DVLEPLVQKI ANEFVSEAAA GEVAAAGLNA IREICVRQPL
AMNDTLLQDL VMYKKSKDKG VMMAAKGLLG LYRQVGAEML KRRDRGKDAT LGLRSGEQQQ
QRFGEEAVGE IEGLELLEKW KEEEKQRKRL EKGLDPDASD DEEEDDEEDW NAWDVEEDDS
DDSGGWINVE SDDEINISDS EDEKPSAKKG RFDAHVSTSD DKENETKEDG IEDAEKPKSN
LATTRILTPA DLAKLQELRT TASVSSLMKN HHAQQKSRAE QTNAQRHMDD PLTAAEIEGL
AALSRGKATR AQKIALLEEH KADREEHKSK AARKKERKES EGKSTTNKEK ARKKNFLMTL
GKAKSKGKRS LVEHRKILKA HAARAKRGGK RGNMGK
//
