ID   A0A0D2FCK6_9EURO        Unreviewed;      1352 AA.
AC   A0A0D2FCK6;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=RNA-dependent RNA polymerase {ECO:0000256|RuleBase:RU363098};
DE            EC=2.7.7.48 {ECO:0000256|RuleBase:RU363098};
GN   ORFNames=PV05_02372 {ECO:0000313|EMBL:KIW57814.1};
OS   Exophiala xenobiotica.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX   NCBI_TaxID=348802 {ECO:0000313|EMBL:KIW57814.1, ECO:0000313|Proteomes:UP000054342};
RN   [1] {ECO:0000313|EMBL:KIW57814.1, ECO:0000313|Proteomes:UP000054342}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 118157 {ECO:0000313|EMBL:KIW57814.1,
RC   ECO:0000313|Proteomes:UP000054342};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA   Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Exophiala xenobiotica CBS118157.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.48; Evidence={ECO:0000256|ARBA:ARBA00024517,
CC         ECO:0000256|RuleBase:RU363098};
CC   -!- SIMILARITY: Belongs to the RdRP family. {ECO:0000256|ARBA:ARBA00005762,
CC       ECO:0000256|RuleBase:RU363098}.
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DR   EMBL; KN847318; KIW57814.1; -; Genomic_DNA.
DR   RefSeq; XP_013318398.1; XM_013462944.1.
DR   STRING; 348802.A0A0D2FCK6; -.
DR   GeneID; 25324280; -.
DR   HOGENOM; CLU_002322_0_1_1; -.
DR   OrthoDB; 2735303at2759; -.
DR   Proteomes; UP000054342; Unassembled WGS sequence.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProt.
DR   InterPro; IPR007855; RNA-dep_RNA_pol_euk-typ.
DR   PANTHER; PTHR23079; RNA-DEPENDENT RNA POLYMERASE; 1.
DR   PANTHER; PTHR23079:SF14; RNA-DEPENDENT RNA POLYMERASE; 1.
DR   Pfam; PF05183; RdRP; 1.
PE   3: Inferred from homology;
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU363098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054342};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU363098};
KW   RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW   ECO:0000256|RuleBase:RU363098};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363098}.
FT   REGION          188..216
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1140..1174
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1352 AA;  153207 MW;  F3B57FECC9AB7014 CRC64;
     MATTPSHIGS KIDWAIDHLN AHWDLRLPKL HGAQVRDAEA KKSLPYKCFT RIRFLCFRIP
     IEKILADFDE QARSIHSKWI FKPSQEKGTL PRLPVTKSMM GREKGENQVI RLSESQREKL
     HQLLFNNLDE HYELARMTKT LSIEQQSDAS FQTAPTTPCK VSLNRTQSLP VTPSKHILYP
     QDNCVDGGLE PVLKDPKTGS AKRSIASPDN KNKRQQKLAE CNYFRPASSS RRPQPPLLSA
     IGQRLEPTSF DTVLTANGSS VFESPDHDHD FFASNDTSIM SSQATGDKAE ESQDLLPTQD
     LQDFLEDEDF NKSFNEMCMP QSSFDPIEVA LSNTFRRQAC LPQNVPFWLC WEIHRLAHLL
     GKLPLDVHGS IMKLCKSNTP SFDRFWEAAK ELSQKMATSP PQKSEVPLWM GTQDKYEDPS
     STKALYLTAS LEWSDNLSQG MFKFRPNEIR LEQSCRLYRK FGADRFLVLF APYFSEGSRR
     GKLRAQDNEN ESVHKKITKF MAEGRHFIAG RYWRVFYVEP EKRKSRKKEH QQPRQKLFLF
     AETGYDMISP PFSLEISTPS LKIDGHHQEI SLETVTQWHM PIAANSTSTD LKLFSRWGIG
     LSKTTPTITL RREEFVRRPD PTNGPVMNDG CALMSYPLAK AIWEASGKPG DMPCAVQARV
     SGAKGLWIVD YQGRQPHRTG DRGYWIEVSD SQLKIKPHPR RRKDADDSLR TFEVLKWAGE
     CKPGHLNIQL ISILEDRGVP RKALQDALTA DTRAYSDSLT AAIGDTKDGR VLLLWMHMNG
     LLGPCEAQRN LGSFPTDRRQ QMRLLLEAGF NPSDCAKIVK CAFKILSDYM TDYVERLWIT
     QSCSTTVFCV PDPTGLLEED EVCMNFSKPV TDPRTGMTEF SLDKMNVLVA RNPAYLASDM
     QKRKAVYIHE LRHYRNVIIF STKGSQPLAS MLSGGDYDGD TCWVCWDPTF VEPFENAHLP
     SMPSEEQCGM VQESRPLSDI FTEARPLEEA MQDFLRACID FNARPSLMGA CSTEHERLVY
     SLSQQQKANK LSSSGTVTLA ALAGYLVDSN KQGWSLDQNS WLAVCVKASG SLKLPEPCFK
     TGSPPRTRKG AYANVIDFLK FEVAAGEKEN ALTGFEKLNP DAGTYDIVLS KYWKDAVEKG
     KTEKSRMADK PRATNRNNKA TAQSRKLTDQ HSDGRTDEAC LSAILEDLSQ QTKNLLQERK
     QLAPVDSIDS SFGESRDSAK YSTAVQRVYE LFQAIEPKDI DHDLRRRYED EKEAHFSHWS
     LLRASCLHYE VCRKGTFPEW VWYVAGRDLC HLKALHHGGN VRLVPEDILG IMQVNSKFAK
     AMLERKTFEA EDVGAGDMID IGMMEDEIMS LD
//