ID A0A0D2GT60_9EURO Unreviewed; 968 AA.
AC A0A0D2GT60;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=DUF2470 domain-containing protein {ECO:0000259|Pfam:PF10615};
GN ORFNames=Z517_04786 {ECO:0000313|EMBL:KIW81760.1};
OS Fonsecaea pedrosoi CBS 271.37.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Fonsecaea.
OX NCBI_TaxID=1442368 {ECO:0000313|EMBL:KIW81760.1, ECO:0000313|Proteomes:UP000053029};
RN [1] {ECO:0000313|EMBL:KIW81760.1, ECO:0000313|Proteomes:UP000053029}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 271.37 {ECO:0000313|EMBL:KIW81760.1,
RC ECO:0000313|Proteomes:UP000053029};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Fonsecaea pedrosoi CBS 271.37.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KN846971; KIW81760.1; -; Genomic_DNA.
DR RefSeq; XP_013285568.1; XM_013430114.1.
DR AlphaFoldDB; A0A0D2GT60; -.
DR STRING; 1442368.A0A0D2GT60; -.
DR GeneID; 25304276; -.
DR VEuPathDB; FungiDB:Z517_04786; -.
DR HOGENOM; CLU_005947_4_1_1; -.
DR OrthoDB; 11415at2759; -.
DR Proteomes; UP000053029; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.
DR Gene3D; 3.20.180.10; PNP-oxidase-like; 1.
DR InterPro; IPR003445; Cat_transpt.
DR InterPro; IPR019595; DUF2470.
DR InterPro; IPR037119; Haem_oxidase_HugZ-like_sf.
DR PANTHER; PTHR31064; POTASSIUM TRANSPORT PROTEIN DDB_G0292412-RELATED; 1.
DR PANTHER; PTHR31064:SF37; TRANSPORTER, PUTATIVE (EUROFUNG)-RELATED; 1.
DR Pfam; PF10615; DUF2470; 1.
DR Pfam; PF02386; TrkH; 1.
PE 4: Predicted;
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000053029};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 221..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 277..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 510..533
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 553..572
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 584..604
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 650..672
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 17..90
FT /note="DUF2470"
FT /evidence="ECO:0000259|Pfam:PF10615"
FT REGION 354..414
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 354..378
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 387..402
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 968 AA; 108358 MW; 32A90DB7A124A62B CRC64;
MSASTTPRGP PDVSAMKARI ITHMNADHQL SLRLYLQHYS HVPSPGTASA QMLDITTEHM
IISSAYGRHV IQFEPPMKSL MEARERLVTM HELCLKQLDL SAIVVSKYVP PDRVWQWALS
GLCLLIFTTF PFRESLRSES GSWIYQVWSL GGVAPWLAEL SYTLAPAVLG VMVVVHGEPP
SSHEVTLDDA REHSILLRAA ALFRKHVLGV FSEFSFINWH YFYFIVTCLV SSLIFWGSST
PAKSVSYVDS LFLCVSAMTE AGLNTVNLSE LNTWQQIMLF LLIIFGSAIF VSSSILHIRK
RAFEKKFAEL AERRINRLHR PRTLTLSLSR RDHVHDNERE AAVASGAIRG RPVSNFHKVD
EHKASSRSRE RPEPIGPHAD VRRNSSVDGT IAGSTSNDPI ASHIRFKVQH PPSEYTETRA
RNIRQSTSFF EGRGVGARRL DNHPRNTQPL EFPYSMPESA IEDELPPDGP LANKLNKYLD
TLHGYLGRNS QFHHLSERER KMLGGIEYDA IRLLSWLVPT YFVLFQLFGA LGVGAWLTAN
RPSTTQENGL NPYWTGAFFA ISAFNNSGMA LLDANAVALN RSYYCLLTLS LLILAGNTLF
PAFLRGILWV FKKLIPEEHP SPDWQRRRRT IQFCLDHPRR VYTNLFPSAA TWWLVASVVV
LNTIDWVAFE LLNIGNEVVD SLPTGFRIVA GLFQALAVRS GGFYVVSIPG LRSGLLVLYV
LMMYLSAFPV TMTIRNTNVY EERSLGIFAD ELPIYQENDD ATRENKKTGF LNGLRRTITM
THGGPSANTP VWTRQDFVRL QLRSQLGHDL WWIAIAIFAI TAIETGQFER DPVSFSTFNV
IFEVVSGYGC VGISVGVPWN NYSFSGAWHL ASKLILCAVM LRGRHRGLPV SIDRAVLLPD
ESLAWAEEED AHMRTSSFCS GGPVLSRAHT SAMTSKDALA RPRTASFGAP GPSILAADAR
ERTIEQVA
//
