ID A0A0D2JXB7_9CHLO Unreviewed; 844 AA.
AC A0A0D2JXB7;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=Peptidase M3A/M3B catalytic domain-containing protein {ECO:0000259|Pfam:PF01432};
GN ORFNames=MNEG_4698 {ECO:0000313|EMBL:KIZ03258.1};
OS Monoraphidium neglectum.
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Sphaeropleales; Selenastraceae; Monoraphidium.
OX NCBI_TaxID=145388 {ECO:0000313|EMBL:KIZ03258.1, ECO:0000313|Proteomes:UP000054498};
RN [1] {ECO:0000313|EMBL:KIZ03258.1, ECO:0000313|Proteomes:UP000054498}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SAG 48.87 {ECO:0000313|EMBL:KIZ03258.1,
RC ECO:0000313|Proteomes:UP000054498};
RX PubMed=24373495; DOI=10.1186/1471-2164-14-926;
RA Bogen C., Al-Dilaimi A., Albersmeier A., Wichmann J., Grundmann M.,
RA Rupp O., Lauersen K.J., Blifernez-Klassen O., Kalinowski J., Goesmann A.,
RA Mussgnug J.H., Kruse O.;
RT "Reconstruction of the lipid metabolism for the microalga Monoraphidium
RT neglectum from its genome sequence reveals characteristics suitable for
RT biofuel production.";
RL BMC Genomics 14:926-926(2013).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|RuleBase:RU003435};
CC Note=Binds 1 zinc ion. {ECO:0000256|RuleBase:RU003435};
CC -!- SIMILARITY: Belongs to the peptidase M3 family.
CC {ECO:0000256|ARBA:ARBA00006040, ECO:0000256|RuleBase:RU003435}.
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DR EMBL; KK100884; KIZ03258.1; -; Genomic_DNA.
DR RefSeq; XP_013902277.1; XM_014046823.1.
DR AlphaFoldDB; A0A0D2JXB7; -.
DR GeneID; 25737575; -.
DR KEGG; mng:MNEG_4698; -.
DR Proteomes; UP000054498; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1370.40; -; 1.
DR Gene3D; 1.10.1370.10; Neurolysin, domain 3; 1.
DR InterPro; IPR024077; Neurolysin/TOP_dom2.
DR InterPro; IPR045090; Pept_M3A_M3B.
DR InterPro; IPR001567; Pept_M3A_M3B_dom.
DR PANTHER; PTHR11804:SF79; MITOCHONDRIAL INTERMEDIATE PEPTIDASE; 1.
DR PANTHER; PTHR11804; PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED; 1.
DR Pfam; PF01432; Peptidase_M3; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003435};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU003435};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049,
KW ECO:0000256|RuleBase:RU003435};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|RuleBase:RU003435};
KW Reference proteome {ECO:0000313|Proteomes:UP000054498};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU003435}.
FT DOMAIN 575..722
FT /note="Peptidase M3A/M3B catalytic"
FT /evidence="ECO:0000259|Pfam:PF01432"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 108..138
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 400..423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 476..497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 531..584
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 733..761
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 552..578
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 844 AA; 85655 MW; 9D1F41D3C7D4F376 CRC64;
MHRRTPERAP QRHPAADADA TQQQARLCGA LLRALEGGAP ATAGAALDGG AWAAALEAPD
VAQQRLACLR AEEAGLLRQL DELMGDPALA PRVLLDVADI GDALGPTVSS SSASAAGGSD
GDGSGSGAGG GRSTPDDAPA ARTVVLTRAA TAALLARAPG AAARRAAHEA GLVPRLAAGG
AALSRLALCR DGMAQLCGAG SFPELCCARL AAPGPVEVAG FLQEAAEKLR PLAERQVERL
LARAQRLPDE VAPGASASGL AVAERKGGGT AAAVRQEDPV PARVPALAPP FEPWDWERLF
EAECAPDAAT LAALAPHLHL GPVLLGFSTL LRRLLGIALL PRPPAGGGGG GDGGGGELWR
PGVWVVAMLH EQRGHLGTLY VDPGAGYGTR VLRHGPWRWA RRGRSSGSGG GGGGGRCGAG
GDGDLSPNEL WAAAIAHLGP VGGAVGPAAA AGSPGSTRVL SWLQAHAASA PGVSIGLSSV
PRGPQGGSAP GSTNGSAAPA DGVLSLSALW ELGHELGHAV HLLLSSSNLG PPVGPGGSFE
EELEKQQQEQ RQGQQREGQQ QQQQEQQQQQ QQEQARPRSP HLSGRFLAPD LLELPSALFE
RILLEPAALA TICSHRETGE PAPAELAAAL ARHYRWRYGS PLAVQDKVCA ALAEQLLGLF
PEDAATQDTW AQTWAEFSST PPWARATSRQ LALMPVVAAH RGTYFSYITC WAWAAHMWRG
TAATLLSPAS GGDGGGGGSG GGGGSGGGGG SGSAAGEGQG AGAEARARAR ARAAMMAVMS
LDASMALESV FRLLLSLGGT GPPEGAAAGR EEAWRGAAEG TGSGDDFVWV PDMPAGLEGW
VFES
//
