ID A0A0D2MDE5_GOSRA Unreviewed; 893 AA.
AC A0A0D2MDE5;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN ORFNames=B456_002G200500 {ECO:0000313|EMBL:KJB15867.1};
OS Gossypium raimondii (New World cotton).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=29730 {ECO:0000313|EMBL:KJB15867.1, ECO:0000313|Proteomes:UP000032304};
RN [1] {ECO:0000313|EMBL:KJB15867.1, ECO:0000313|Proteomes:UP000032304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23257886; DOI=10.1038/nature11798;
RA Paterson A.H., Wendel J.F., Gundlach H., Guo H., Jenkins J., Jin D.,
RA Llewellyn D., Showmaker K.C., Shu S., Udall J., Yoo M.J., Byers R.,
RA Chen W., Doron-Faigenboim A., Duke M.V., Gong L., Grimwood J., Grover C.,
RA Grupp K., Hu G., Lee T.H., Li J., Lin L., Liu T., Marler B.S., Page J.T.,
RA Roberts A.W., Romanel E., Sanders W.S., Szadkowski E., Tan X., Tang H.,
RA Xu C., Wang J., Wang Z., Zhang D., Zhang L., Ashrafi H., Bedon F.,
RA Bowers J.E., Brubaker C.L., Chee P.W., Das S., Gingle A.R., Haigler C.H.,
RA Harker D., Hoffmann L.V., Hovav R., Jones D.C., Lemke C., Mansoor S.,
RA ur Rahman M., Rainville L.N., Rambani A., Reddy U.K., Rong J.K.,
RA Saranga Y., Scheffler B.E., Scheffler J.A., Stelly D.M., Triplett B.A.,
RA Van Deynze A., Vaslin M.F., Waghmare V.N., Walford S.A., Wright R.J.,
RA Zaki E.A., Zhang T., Dennis E.S., Mayer K.F., Peterson D.G., Rokhsar D.S.,
RA Wang X., Schmutz J.;
RT "Repeated polyploidization of Gossypium genomes and the evolution of
RT spinnable cotton fibres.";
RL Nature 492:423-427(2012).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the importin beta family. Importin beta-2
CC subfamily. {ECO:0000256|ARBA:ARBA00038423}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM001741; KJB15867.1; -; Genomic_DNA.
DR RefSeq; XP_012467606.1; XM_012612152.1.
DR AlphaFoldDB; A0A0D2MDE5; -.
DR EnsemblPlants; KJB15867; KJB15867; B456_002G200500.
DR GeneID; 105785941; -.
DR Gramene; KJB15867; KJB15867; B456_002G200500.
DR KEGG; gra:105785941; -.
DR OrthoDB; 276400at2759; -.
DR Proteomes; UP000032304; Chromosome 2.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000357; HEAT.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR040122; Importin_beta.
DR PANTHER; PTHR10527:SF3; FI21453P1-RELATED; 1.
DR PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR Pfam; PF02985; HEAT; 1.
DR Pfam; PF13513; HEAT_EZ; 1.
DR Pfam; PF03810; IBN_N; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000032304};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 38..106
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
FT REGION 324..361
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 335..354
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 893 AA; 99188 MW; 9728879F562773EB CRC64;
MAAAGSASWQ PQEEGLKEIC GLLEQQISPS SSADKSQIWQ QLQHYSQFPD FNNYLAFILA
RAEGKSVEIR QAAGLLLKNN LRTAYKMMSP AHQQYIKSEL LPCLGAADKH IRSTVGTIIS
VVVQQGGILG WPELLQAFIN CLDSNDLNHM EGAMDALSKI CEDIPQVLDS DVPGLAERPI
NIFLPRLFQF FQSPHASLRK LSLGSVNQYI MLMPSALYAS VDKYLHGLFG LANDPAAEVR
KLVCAAFVQL IEVRPSVLEP HMKNVIEYML QVNKDTDDEV ALEACEFWSA YCDAQLPPEI
LREYLPRLIP ILLSNMAYAD DDESLAEAEE DESLPDRDQD LKPRFHTSRF HGSEDAEDDD
DDSFNVWNLR KCSAAALDVL SNVFGDEILP TLMPIIQAKL AATGDEAWKD REAAVLALGA
VGEGCINGLY PHLSEIVAFL IPLLDDKFPL IRSISCWTLS RFSKYIVQDS GHQKGYEQFD
AALMGLLRRI LDTNKRVQEA ACSAFATLEE EAAEELAPRL EVILQHLMCA FGKYQRRNLR
IVYDAIGTLA DAVGGELNQP VYLEILMPPL IAKWHQVPNS DKDLFPLLEC FTSIAQALGT
GFTQFAQPVF QRCINIIQTQ QLAKVDPVSA GVQYDKEFIV CSLDLLSGLT EGLGSGIESL
VSQSNLRDLL LQCCMDDASD VRQSAFALLG DLARVCPVHL HPRLSEFLDI AAKQLNTPKL
KETISVANNA CWAIGELAIK VRKEISPIVM TVISCLVPIL QHAEGLNKSL VENSAITLGR
LAWVCPDLVS PHMEHFMQSW CIALSMIRDD IEKEDAFRGL CAMVRANPSG ALSSLVFMCK
AIASWHEIRS EELHNEVCQV LHGYKQMLRN GAWDQCMSAL EPPVKDKLSK YQV
//
