ID A0A0D2NRI4_9CHLO Unreviewed; 620 AA.
AC A0A0D2NRI4;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Cytochrome P450 {ECO:0000313|EMBL:KIZ06916.1};
DE EC=1.14.14.1 {ECO:0000313|EMBL:KIZ06916.1};
GN ORFNames=MNEG_1042 {ECO:0000313|EMBL:KIZ06916.1};
OS Monoraphidium neglectum.
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Sphaeropleales; Selenastraceae; Monoraphidium.
OX NCBI_TaxID=145388 {ECO:0000313|EMBL:KIZ06916.1, ECO:0000313|Proteomes:UP000054498};
RN [1] {ECO:0000313|EMBL:KIZ06916.1, ECO:0000313|Proteomes:UP000054498}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SAG 48.87 {ECO:0000313|EMBL:KIZ06916.1,
RC ECO:0000313|Proteomes:UP000054498};
RX PubMed=24373495; DOI=10.1186/1471-2164-14-926;
RA Bogen C., Al-Dilaimi A., Albersmeier A., Wichmann J., Grundmann M.,
RA Rupp O., Lauersen K.J., Blifernez-Klassen O., Kalinowski J., Goesmann A.,
RA Mussgnug J.H., Kruse O.;
RT "Reconstruction of the lipid metabolism for the microalga Monoraphidium
RT neglectum from its genome sequence reveals characteristics suitable for
RT biofuel production.";
RL BMC Genomics 14:926-926(2013).
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971};
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR EMBL; KK100316; KIZ06916.1; -; Genomic_DNA.
DR RefSeq; XP_013905935.1; XM_014050481.1.
DR AlphaFoldDB; A0A0D2NRI4; -.
DR STRING; 145388.A0A0D2NRI4; -.
DR GeneID; 25727580; -.
DR KEGG; mng:MNEG_1042; -.
DR OrthoDB; 1611592at2759; -.
DR Proteomes; UP000054498; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0070330; F:aromatase activity; IEA:UniProtKB-EC.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR Gene3D; 1.10.630.10; Cytochrome P450; 2.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR24301; THROMBOXANE-A SYNTHASE; 1.
DR PANTHER; PTHR24301:SF2; THROMBOXANE-A SYNTHASE; 1.
DR Pfam; PF00067; p450; 2.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 2.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|RuleBase:RU000461};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU000461};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU000461};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033,
KW ECO:0000256|RuleBase:RU000461};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU000461};
KW Reference proteome {ECO:0000313|Proteomes:UP000054498};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 50..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 328..361
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 620 AA; 66558 MW; 6593547FDE966A05 CRC64;
MIDLHEAAAV GLAVFSLATI LLWTTNRWKL RRIPGFHEYL DMCRRQYGRV FKIYLGSGAF
IVVADPHLAR KVNYRLIDRS IGSQLSADKK GSDNDGLLGL AAAKGEEWRQ LRMAWQPAFA
SGSLAHYSSL MDSCAVRLCD TLEGAAKEGR EVDIFRALGT MTMGVVGTTA FGIDFHTLDD
PDSPSAEEGL RLVKASQTVF SSSSLVAGTF YQPLLLMFPK AVPFVQWLAS TLPDRKLVQL
SEARKIIRNV GYSLIQNWRS AHPDQAATGA DKAAPPAVAK VEATLEELQG EAPGLLVQAA
THAGAPEAAA DANGFVNGVG AVEAANGDDA TSAARDQDGA AAAAAQPQDK PRPRGATDVE
PGSFLGLLLR ARDRASGAAK FSDASITAQA STFILAGYET TANALSYAVY NIALSPRVQE
RLHAEIDAFG RTRQASTCAA EGPRTHPAPV THADLGEFPY AEAVVKEALR LYPPATLTSR
VVTKQEGMTL IPGVTLKKGA NLFTAPYCYQ RDEAYWPRPL EFAPERFLPE GSALAPSTDD
AWTPFGAGPR MCIGWRFALN EAKIALVRLH QRFSFELRPG QVPLKLRQGI TLSPADGVWV
RPIARGRGVE PVSVPPAAAA
//
