ID A0A0D2R5J5_GOSRA Unreviewed; 369 AA.
AC A0A0D2R5J5;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Vacuolar processing enzyme {ECO:0008006|Google:ProtNLM};
GN ORFNames=B456_010G103000 {ECO:0000313|EMBL:KJB65607.1};
OS Gossypium raimondii (New World cotton).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=29730 {ECO:0000313|EMBL:KJB65607.1, ECO:0000313|Proteomes:UP000032304};
RN [1] {ECO:0000313|EMBL:KJB65607.1, ECO:0000313|Proteomes:UP000032304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23257886; DOI=10.1038/nature11798;
RA Paterson A.H., Wendel J.F., Gundlach H., Guo H., Jenkins J., Jin D.,
RA Llewellyn D., Showmaker K.C., Shu S., Udall J., Yoo M.J., Byers R.,
RA Chen W., Doron-Faigenboim A., Duke M.V., Gong L., Grimwood J., Grover C.,
RA Grupp K., Hu G., Lee T.H., Li J., Lin L., Liu T., Marler B.S., Page J.T.,
RA Roberts A.W., Romanel E., Sanders W.S., Szadkowski E., Tan X., Tang H.,
RA Xu C., Wang J., Wang Z., Zhang D., Zhang L., Ashrafi H., Bedon F.,
RA Bowers J.E., Brubaker C.L., Chee P.W., Das S., Gingle A.R., Haigler C.H.,
RA Harker D., Hoffmann L.V., Hovav R., Jones D.C., Lemke C., Mansoor S.,
RA ur Rahman M., Rainville L.N., Rambani A., Reddy U.K., Rong J.K.,
RA Saranga Y., Scheffler B.E., Scheffler J.A., Stelly D.M., Triplett B.A.,
RA Van Deynze A., Vaslin M.F., Waghmare V.N., Walford S.A., Wright R.J.,
RA Zaki E.A., Zhang T., Dennis E.S., Mayer K.F., Peterson D.G., Rokhsar D.S.,
RA Wang X., Schmutz J.;
RT "Repeated polyploidization of Gossypium genomes and the evolution of
RT spinnable cotton fibres.";
RL Nature 492:423-427(2012).
CC -!- SIMILARITY: Belongs to the peptidase C13 family.
CC {ECO:0000256|ARBA:ARBA00009941}.
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DR EMBL; CM001749; KJB65607.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D2R5J5; -.
DR MEROPS; C13.002; -.
DR EnsemblPlants; KJB65607; KJB65607; B456_010G103000.
DR Gramene; KJB65607; KJB65607; B456_010G103000.
DR OMA; DQGTRWA; -.
DR Proteomes; UP000032304; Chromosome 10.
DR GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0051603; P:proteolysis involved in protein catabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1460; -; 1.
DR InterPro; IPR043577; AE.
DR InterPro; IPR001096; Peptidase_C13.
DR PANTHER; PTHR12000; HEMOGLOBINASE FAMILY MEMBER; 1.
DR PANTHER; PTHR12000:SF42; LEGUMAIN; 1.
DR Pfam; PF01650; Peptidase_C13; 1.
DR PIRSF; PIRSF500139; AE; 1.
DR PIRSF; PIRSF019663; Legumain; 1.
DR PRINTS; PR00776; HEMOGLOBNASE.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000032304};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..369
FT /note="Vacuolar processing enzyme"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002249959"
FT ACT_SITE 171
FT /evidence="ECO:0000256|PIRSR:PIRSR019663-1"
FT ACT_SITE 213
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR019663-1"
SQ SEQUENCE 369 AA; 40946 MW; A490CEB60FDC87C6 CRC64;
MTTLVTGVFL LLLSVAGVVS AARYITGDVL RLPSEASRFF RWRSDDDEVG GTRWAVLIAG
SNGYWNYRHQ ADVCHAYQLL RNGGLKEENI IVFMYDDIAF NEENPRPGVI INNPHGDDVY
KGVPKDYTGE DVNVHNFFAA LLGNKSAITG GSGKVVDSGP DDHIFIYYTD HGGPGVLGMP
TFPYLYADDL IDVLKKKHAS GTYKSMVFYL EACESGSIFE GLLPQGLNIY ATTASNAEES
SWGTYCPGEY PSPPPEYETC LGDLYSVAWM EDSDMHNLRT ETLHQQYELV KKRTINGNSA
YGSHVMQYGD VGLSKDSLFA YLGTNPANDN FTFVDENSLV PPTKAVNQRD ADLVHFWYKV
LSQGTRRLC
//
