ID A0A0D2UXB3_GOSRA Unreviewed; 997 AA.
AC A0A0D2UXB3;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN ORFNames=B456_011G236200 {ECO:0000313|EMBL:KJB73504.1};
OS Gossypium raimondii (New World cotton).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=29730 {ECO:0000313|EMBL:KJB73504.1, ECO:0000313|Proteomes:UP000032304};
RN [1] {ECO:0000313|EMBL:KJB73504.1, ECO:0000313|Proteomes:UP000032304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23257886; DOI=10.1038/nature11798;
RA Paterson A.H., Wendel J.F., Gundlach H., Guo H., Jenkins J., Jin D.,
RA Llewellyn D., Showmaker K.C., Shu S., Udall J., Yoo M.J., Byers R.,
RA Chen W., Doron-Faigenboim A., Duke M.V., Gong L., Grimwood J., Grover C.,
RA Grupp K., Hu G., Lee T.H., Li J., Lin L., Liu T., Marler B.S., Page J.T.,
RA Roberts A.W., Romanel E., Sanders W.S., Szadkowski E., Tan X., Tang H.,
RA Xu C., Wang J., Wang Z., Zhang D., Zhang L., Ashrafi H., Bedon F.,
RA Bowers J.E., Brubaker C.L., Chee P.W., Das S., Gingle A.R., Haigler C.H.,
RA Harker D., Hoffmann L.V., Hovav R., Jones D.C., Lemke C., Mansoor S.,
RA ur Rahman M., Rainville L.N., Rambani A., Reddy U.K., Rong J.K.,
RA Saranga Y., Scheffler B.E., Scheffler J.A., Stelly D.M., Triplett B.A.,
RA Van Deynze A., Vaslin M.F., Waghmare V.N., Walford S.A., Wright R.J.,
RA Zaki E.A., Zhang T., Dennis E.S., Mayer K.F., Peterson D.G., Rokhsar D.S.,
RA Wang X., Schmutz J.;
RT "Repeated polyploidization of Gossypium genomes and the evolution of
RT spinnable cotton fibres.";
RL Nature 492:423-427(2012).
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DR EMBL; CM001750; KJB73504.1; -; Genomic_DNA.
DR RefSeq; XP_012455598.1; XM_012600144.1.
DR AlphaFoldDB; A0A0D2UXB3; -.
DR STRING; 29730.A0A0D2UXB3; -.
DR EnsemblPlants; KJB73504; KJB73504; B456_011G236200.
DR GeneID; 105777084; -.
DR Gramene; KJB73504; KJB73504; B456_011G236200.
DR KEGG; gra:105777084; -.
DR eggNOG; ENOG502QRJR; Eukaryota.
DR OMA; HSFRQNT; -.
DR OrthoDB; 357813at2759; -.
DR Proteomes; UP000032304; Chromosome 11.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR32472:SF11; DISEASE RESISTANCE PROTEIN (TIR-NBS CLASS); 1.
DR PANTHER; PTHR32472; DNA REPAIR PROTEIN RADA; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13676; TIR_2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000032304}.
FT DOMAIN 162..281
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 434..456
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 997 AA; 113398 MW; BADAD1F68A946E22 CRC64;
MEMGSTLNMD FQEDSGTLGS LPVTTSRNMS SSSSAFFSAN QSPFFSPRSS TCQFSESTRS
DAQCDSATLS ADPPSSCSGI QGTECLGNAR FDLPDMKLEP TACISSDFRK SDHVVSNGTL
SSYGHVGDNG YYDLIAKHRK QMRSHDMSFS PVPISLSSNR NRSYDIYIGL HGRKPSLQRF
ANWLRAELEL QGMSCFVSDR ARFRSSRKLG LMEKAMDVSS FGVVILTRKS FKNPYTIEEL
RFFSSKKNLV PIYFDLSPGD CLVRDIVEKR GELWEKHGGE LWFLYGGLEK EWKEAVNGLF
RVDEWKLEAQ DGSWRDCISR AVSLLAMRLG RRSVVEQMMR WREKVEKEEF PFPRNENFVG
RKKELSELEF ILFGDISGET ERDYFELKAR SKRKNLMIGW SKSSSVEERL GKRQWGSGSR
KGKEPVIWKE SEKEIEMQST ERQQNQRPKG GGWTSRRKKS AKIVYGKGIA CVTGDSGIGK
TELLLEFAYR YHQRYKMVLW IGGESRYIRQ NYLNLRSLLE VDVRVENCID KSKMKSFDEQ
EEAAISRIRK ELMRNIPFLV VIDNLESEKD WWDQKLIMDL LPRFGGETHI VISTRLPRVM
NLEPLKLSYL SAVEAMSLMQ VSAKEYPIAE IDVLRTIEEK VGRLTLGLAI VGAILSELPI
NPSRLLDTIN RMPLRDISLS GREAHSLRKN TFLLQLFEVC FSIFDHAVGL RSLATRMVLV
SGWFAPAAIP VSLLALAARK IPEKHKRTCF WRKVLRSLTC GFSSSYSKRS ETEASSMLLR
FNIARSSTKE GYVHFNELIK VYARKRGVTG VAHAMVQAIV SRGSLSLHSE HIWAACFLLF
GFGNDPIVVE LRVSELLYLV KEVILPLAIR TFITFSRCRP ALELLQLCTN ALEVADQAFV
TPVEKWFDKS LCWRPIKTNA QLNPCLWQDL ALSRATVLET RAKLLLRGGQ FDIGDDLIRK
AIFIRTSICG EDHPDTVSAR ETLSKLTRLL ANVQTHT
//
