ID A0A0D2X1P1_CAPO3 Unreviewed; 1677 AA.
AC A0A0D2X1P1;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Myosin-VIIa motor domain-containing protein {ECO:0000313|EMBL:KJE91149.1};
GN ORFNames=CAOG_002327 {ECO:0000313|EMBL:KJE91149.1};
OS Capsaspora owczarzaki (strain ATCC 30864).
OC Eukaryota; Filasterea; Capsaspora.
OX NCBI_TaxID=595528 {ECO:0000313|EMBL:KJE91149.1, ECO:0000313|Proteomes:UP000008743};
RN [1] {ECO:0000313|Proteomes:UP000008743}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 30864 {ECO:0000313|Proteomes:UP000008743};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Capsaspora owczarzaki ATCC 30864.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; KE346362; KJE91149.1; -; Genomic_DNA.
DR RefSeq; XP_004349077.1; XM_004349027.2.
DR STRING; 595528.A0A0D2X1P1; -.
DR EnsemblProtists; KJE91149; KJE91149; CAOG_002327.
DR GeneID; 14900395; -.
DR eggNOG; KOG3686; Eukaryota.
DR eggNOG; KOG4229; Eukaryota.
DR InParanoid; A0A0D2X1P1; -.
DR OrthoDB; 1094820at2759; -.
DR PhylomeDB; A0A0D2X1P1; -.
DR Proteomes; UP000008743; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 2.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR035974; Rap/Ran-GAP_sf.
DR InterPro; IPR000331; Rap/Ran_GAP_dom.
DR PANTHER; PTHR13140:SF856; HEAVY CHAIN, UNCONVENTIONAL MYOSIN; 1.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR Pfam; PF00063; Myosin_head; 2.
DR Pfam; PF02145; Rap_GAP; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR PROSITE; PS50096; IQ; 2.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS50085; RAPGAP; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW Reference proteome {ECO:0000313|Proteomes:UP000008743}.
FT DOMAIN 10..835
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 1243..1474
FT /note="Rap-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50085"
FT REGION 295..334
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 679..701
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 758..781
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 947..978
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1030..1055
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1567..1677
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..327
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1041..1055
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1606..1620
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1642..1671
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 119..126
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1677 AA; 186529 MW; C3EAC8F450EB5FF5 CRC64;
MVDTDKPEDA VFDDMVEIGD LHELSILANL QRRFERDIIY TYIGKIVLVA VNPYKQLSVA
PPQNSINPFA KLSLHGAELA NTYRMKRAGE LPPHIFATAQ EAYHHMMRDR KSQCVVVSGE
SGAGKTFSTQ LILNYLANAS AAAADKFGSV PGLPTSTSTS TSTSTSTTTA AASVQTAGAL
TMKDSIGKRL LAAGPVLQAF GNATTVYNPN SSRFGNYIQI VFDSNGRIQG ANIQQYLLEK
SRIIQQADRE RNYHVFYNLL TFEDLVAELQ MGPPSNYAYL IPHIPAAPNA AGAAPHLSAM
PKSSSQSNFL NVNSGQPAPN RRSSMRRTSD AGPLIDDVGD GIKLRASLKT LEFTNEEVSD
LFRVVFGVLL IGNVNLVAGE SSNMESTAIR NPVLLDMISK VLGLSQAHLK ALMTEQVSRF
STGEVVTRTM SVQQALTTRD SIAKALYACI FHWVANRINR VIKGALGTDR PGGNSSSSTS
AAELDVNALP AGCTAINVLD IFGFENFAHN SFEQLCINFA NEQLHQFFST YMFKVEQAVY
VEEQINWEQM SFPDNQPCLD LIGHAKLSIL SLADEECIMP KATDLTLMEK ITKHNSTHPF
FKAKANKLFG VRHYAGLVFY DPQGILVKNN DSLGEEALNL LRQSKKPLIG DMINLYYGPG
KSSTAGKRKT IGTQFRDSLK QLMTSLSACN PFFVRCIKPN ISITPGLFEE AIVLEQLKYL
GLLETVKIRK HGFPFRYKFD EFVARYRILL PRPPKPATSA TYGLGRTATK APSTPAPKPL
DSRTLTQQLL DSLGKTVPSK SKGGAAAAPQ SLYKMGKTRV FLPLEYEMNL EQLLELAKVT
CARRIQRTFR KWFHTRKLNV KARAIQRFYR TYRARRYFLK ARAIAKALQP VARGYIARVD
ANKLRTAKRI EREERLRRER EEEERRKAEL AALERETKER QEAERRRIAE EEAERQRVEA
ERLAEERRLR EQEEEKERLE RMRIAVEQAE RERIEREKID MLAAKERHQQ SNATASMAAR
SFQDLSKEVD NDARANPNDE EAPLTSGNDG ASSGDLLSPS SLAAAAAAAA TSRMLASPVH
ALPPVLESCA GYQIEGPSLV RARRGAAFIE VTRDNRWWKH FFYQKEHITV AAKHESLGTV
LVSIVARSAE DIVSTAATDP ATYRAIVWTK LGFGLASFSP PDQDYSEAAG EIVKGKKKQY
RAHELMDMAV DRFGHTLGDK WKLRENCFQV RNSDCDDKLL RLEEDNHKFY YPQHYKFGVL
LMREGQTDET LLFSNCNDGR AGEPPRCPSF DAFLDLIGTK VRLQGFDKFR GGLDVKTDLT
GTHSYAATRD AGPSTDEIMF HVSSMLPFAR DQPQQPERKR HIGNDVCLVV FNDGTTPYAP
QTVKSHFIHV LIVVHLVSAA SEDGSVPAQY RVGVAYKDTV SEFSPPITHE LWAHGPELRE
FLINKLINGQ RAALKCESFQ EPFRKYRSSV LDQLYHVAAE QRGEKAWRSR ASKQTVKTHL
GSIRKFNSMD SDDLHALRLL RYEQDERKAA EKDFAEAAKK AKGGSLFLSG KRSSSATKLQ
LENRFSSVTE ATTSSAPSSP VAVPRRGRAT TMVGAPSPLA LEGGPISPTS PTSPQSEKKR
WRLLTSLRGT PKSPDGSSPV EPLSPVDTNF PDANTTLSSS PPIVNKQVAQ LRQQEDM
//
