ID A0A0D2X4J9_CAPO3 Unreviewed; 2815 AA.
AC A0A0D2X4J9;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Neutral sphingomyelinase activation associated factor {ECO:0000313|EMBL:KJE96189.1};
GN ORFNames=CAOG_006548 {ECO:0000313|EMBL:KJE96189.1};
OS Capsaspora owczarzaki (strain ATCC 30864).
OC Eukaryota; Filasterea; Capsaspora.
OX NCBI_TaxID=595528 {ECO:0000313|EMBL:KJE96189.1, ECO:0000313|Proteomes:UP000008743};
RN [1] {ECO:0000313|Proteomes:UP000008743}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 30864 {ECO:0000313|Proteomes:UP000008743};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Capsaspora owczarzaki ATCC 30864.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KE346370; KJE96189.1; -; Genomic_DNA.
DR RefSeq; XP_004345297.1; XM_004345247.2.
DR EnsemblProtists; KJE96189; KJE96189; CAOG_006548.
DR GeneID; 14896555; -.
DR eggNOG; KOG1787; Eukaryota.
DR InParanoid; A0A0D2X4J9; -.
DR OMA; NERGPWG; -.
DR OrthoDB; 5478899at2759; -.
DR PhylomeDB; A0A0D2X4J9; -.
DR Proteomes; UP000008743; Unassembled WGS sequence.
DR CDD; cd06071; Beach; 1.
DR CDD; cd01201; PH_BEACH; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR046851; NBCH_WD40.
DR InterPro; IPR010508; NBEA-like_DUF1088.
DR InterPro; IPR031570; NBEA/BDCP_DUF4704.
DR InterPro; IPR046852; Neurobeachin_a-sol.
DR InterPro; IPR023362; PH-BEACH_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13743; BEIGE/BEACH-RELATED; 1.
DR PANTHER; PTHR13743:SF160; NEUROBEACHIN; 1.
DR Pfam; PF02138; Beach; 1.
DR Pfam; PF06469; DUF1088; 1.
DR Pfam; PF15787; DUF4704; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR Pfam; PF20426; NBCH_WD40; 1.
DR Pfam; PF20425; Neurobeachin; 1.
DR Pfam; PF14844; PH_BEACH; 1.
DR SMART; SM01026; Beach; 1.
DR SMART; SM00320; WD40; 4.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS51783; PH_BEACH; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008743};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 1916..2025
FT /note="BEACH-type PH"
FT /evidence="ECO:0000259|PROSITE:PS51783"
FT DOMAIN 2087..2377
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT REPEAT 2545..2576
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 714..739
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1032..1069
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1216..1247
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1344..1375
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1833..1910
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..54
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1037..1064
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1852..1899
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2815 AA; 305652 MW; 75A7343DD3057544 CRC64;
MASLLRRAGS AARHASSALQ SGLAHQQGSS ASATNSTLSS SSSSSSSPSS ASALGSGSAG
GFSSDFPAPP VAVAPMLAPM PSQSQLDDED DTAQQAALKA SLANKPVVDL ILAIEDAKSP
SAQIVSALFD LLVVGEFHLH SNYEIRAIDA LYVLLDVAPH CSVNVQAEIW NTLIAILEKS
ITNLELCSRW GLIEKLLGRI HVFKDDIALT KVLQLVEVLG RYCISVRELR SILRTLKSSD
QKLRPRFSVK LMNVLRSMAQ EERPNVYFHF SGNQSGIMLP CVTKWPYQTG FTFSTWFRIE
PPDPELLKQR LEKPKPYLYC FKTDKGLGYS GHFDGKKLTI SFKLSMGKIT SDCDVPFDFE
PRQWYMFTAV HNYRRIGSSE LMCYVNGQLV LKCDIKFVTT TDLFTHCFLG TSTTPSVRTS
FCGQIGATYV FNDALSSAQV AAIHALKSDY MSNFRQATES SVPLTTVHRK TLFDGGRLTS
AIMFTYNPKA VSGNVCFECS PNDANQWFSA ESSGAILLNG SRTVVTHSYH HALESIGGIQ
TLFPLVSQFD HADQPRDGAL GIVYEPDPAY SLTLLSLFAE TLAASTTSQS QLDQHRGFTV
LAHLLDDVLP TNMSRQVLEV LLQLAQSLRK AAETNSLAAQ SLFRDLFDQV LFRFNLWICS
DVAVQKRLLG VLASDLVRTE SVNVRSLIGV QRLMDLISNF FWLPDPATAA AAAAISATTE
PPASRAEPAP DNEDETQSPT GAARYQLAGQ PVLHPVTKRA VAQRPNTSDI VELRMIVLTI
IKQLVLDGSG ITADELSAIL NYIVANLSIN QEWHVIDAVE LILTLMCDHP EPILGLFEQQ
NGIQVALSLL SAKSVPVRGF GLKILGKLLS WLPTKRADKL IQQHQLFSLI STTLSMYSTE
LDKTTYNALF EIMLNQVTKQ LVPDRFVSRD ATSRIAHPGV LRTLFDLVTH DSSSAGTTTL
FRLLGDLVML LSHEPDNRRI FLAFPNWQNW FVTFLKSVTR VQDCGFSAHH LVNPAAAHSS
VLVVSGNRQS AAPASARPAS PTPPPADPSS SSDASLPPTP TPPGAAAAAQ SFSGSAAPAA
IVASAAQENL QCAELICTLF RVLLCHALKN EREGYQVWVD TIAVFKHEDL SNSVLTFPEL
HFRFICDVLL AVEADMQAWR TNDKKSGADF VNMRENSLFV FNVAFFVSIV AENVLTLKDA
YAALLTVCSK PTSASPSAAN ANLSGQTAPG LAPPASERSE RSERSSGMSA AGAIVGAIGG
ALGGAWSTLG AVAANTASGG SSNTVPGVTS VTGTSLFSRN RPSNLFETAP NSAEDNSEEP
SFYDSRAMLM VNMASESGAT AGLIAGAEPT DPTTEDADEQ DLDASDKTSA TIESASSRPV
LDVQPLVTRL IHLVDLLVFA STISYDQLET RRGMSIGGIL RQCLRLVCCR IQTQLTASIS
TQTAGDATPA AMTNRYLELD AHLLRLSELR RQLVEVMMGH ESERFHRLQH YLMIRLKEQE
SKIDNLRCVL DRMDVKRLRA IVYRDMDGHL RQAQQLLLAE LQFLSVIIVS EYKSILDPSN
SDPNVPDDDG SLMTSRIEAA FSSVTPLIHE SCTDFKPFLS KAFVTPSGTE LITKESPCLR
AAASVIEVVM ALTSSDWQRC LRDVAEQAYR DMVLEGQHLA ARYERELRLR SSNAQLAIQA
AASIELEAQS SSMFAINKFL GMTFADEANR LVAAQAALRR GTTTASRVYA KVFDLLTNEN
GPWGLPADSA EQKPITFMKL DSTEDALRRR ARLVPNRYGS DHQEAILLIE STNNDADNAG
AVSPGVEPIT VGGAMAAMRA ATKLKLALKA KTATAAHDDD MPFDDDSMND SMNELPAASS
SSAAAASPAS SSSTPASSHG TANGAAGSAS ATATSAPPAA TPALPQLGGA DPLASTAGKR
VLLSAPCEMI TPGGKIPGTF KIVTGMFSFT ADEDSAAFKE LQQNPYRVYL DVVHGQWTFD
EVTIVYPRRY MLRHSAIEVF LSNHTTLMVN FADRRVARRA LRALPNLASG TEATLGSNFR
EAARGGLAAM MTTGATGAGA GAGAGANATN AGAVSGGGLS NGSSASSMWA RIFLRSDATA
RWQRREISNF EYLMLLNTMA GRSFNDLNQY PVFPWVLTDY ESENLDLKDP SVFRDLSKPI
GALNPTRLET FVERFESWED EEVPAFHYGS HYSAAGYVLF WLIRLEPFST LFLNLQGGHF
DHAGRTFASV GQAWRNCMDS TTDVKELIPE LYSLPEMLVN ANKYPFGKDD DGATVDNVTL
PPWAHGSSEE FVRLHREALE SDYVSEHLHE WIDLIFGYKQ RGPEAEKAVN VFYYLTYDGA
VDIDAISDPV MRQAVEQQIA SFGQTPCKLL NTPHPRRGDL DAAAAAQAAG SNATAGAAKA
VTPSESTSHW NAESLHSPLL KLPITSDDPV CFVTGNVNLK SIVTVSTSRM FGSHTWTYNA
PATMEEGDLA FDLMLDPVLE EQTSGEPVAH SSIVRRLPEP LDQRIAVSSR CFATSADNSV
LVTCGYWDNS FKCYALDSGK LLQSVHSHRD VVTCMAMSAD GTLLVTGSRD STVRVWPWST
KKQRCADQPS STLFGHEHMV SCIAVSTSFD LVASGSRDVV LLHTIGGDFL RSLRHPCFRR
VVLVCISPKN GSVTVAYSDK GGALALFSMN GKLLATEDLD ETVNAMCHDK NGDFLFTGGA
RSCLMVKHAF SLKHVHIYAS NHSPLCSIAL TSDERYVLSG LESGLLVVNS VDFSTWRRDA
FEPHSALIPQ EQASVLQDLQ ERDVKRKKLQ HDQLFVQQQK LLARPNSVAE VRAAL
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