ID A0A0D2X5L5_CAPO3 Unreviewed; 732 AA.
AC A0A0D2X5L5;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 13-SEP-2023, entry version 24.
DE RecName: Full=GPI inositol-deacylase {ECO:0008006|Google:ProtNLM};
GN ORFNames=CAOG_008071 {ECO:0000313|EMBL:KJE98019.1};
OS Capsaspora owczarzaki (strain ATCC 30864).
OC Eukaryota; Filasterea; Capsaspora.
OX NCBI_TaxID=595528 {ECO:0000313|EMBL:KJE98019.1, ECO:0000313|Proteomes:UP000008743};
RN [1] {ECO:0000313|Proteomes:UP000008743}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 30864 {ECO:0000313|Proteomes:UP000008743};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Capsaspora owczarzaki ATCC 30864.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KJE98019.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 30864 {ECO:0000313|EMBL:KJE98019.1};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Capsaspora owczarzaki ATCC 30864.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the GPI inositol-deacylase family.
CC {ECO:0000256|ARBA:ARBA00006931}.
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DR EMBL; KE346376; KJE98015.1; -; Genomic_DNA.
DR EMBL; KE346376; KJE98016.1; -; Genomic_DNA.
DR EMBL; KE346376; KJE98017.1; -; Genomic_DNA.
DR EMBL; KE346376; KJE98018.1; -; Genomic_DNA.
DR EMBL; KE346376; KJE98019.1; -; Genomic_DNA.
DR EMBL; KE346376; KJE98020.1; -; Genomic_DNA.
DR EMBL; KE346376; KJE98021.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D2X5L5; -.
DR EnsemblProtists; KJE98015; KJE98015; CAOG_008071.
DR EnsemblProtists; KJE98016; KJE98016; CAOG_008071.
DR EnsemblProtists; KJE98017; KJE98017; CAOG_008071.
DR EnsemblProtists; KJE98018; KJE98018; CAOG_008071.
DR EnsemblProtists; KJE98019; KJE98019; CAOG_008071.
DR EnsemblProtists; KJE98020; KJE98020; CAOG_008071.
DR EnsemblProtists; KJE98021; KJE98021; CAOG_008071.
DR Proteomes; UP000008743; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR012908; PGAP1-like.
DR InterPro; IPR039529; PGAP1/BST1.
DR PANTHER; PTHR15495:SF7; GPI INOSITOL-DEACYLASE; 1.
DR PANTHER; PTHR15495; NEGATIVE REGULATOR OF VESICLE FORMATION-RELATED; 1.
DR Pfam; PF07819; PGAP1; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000008743};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 446..470
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 482..504
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 524..550
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 571..604
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 624..643
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 655..675
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 687..707
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 732 AA; 79322 MW; 823D9CAFA469F2B7 CRC64;
MGGVVARLLL EQHPELVPHV ALVVTLATPQ HSLAGVLDAH LRSIHASIST SSRCYNVTRP
FPPVLSIAGG LADTLIRQDL VLVDDAPPGR IVQGVSSSIP YVWAAADHNC IMWCNQLALR
IILLLGRALP SPKASGGEIA TTIQSLFFEE QPLLSSDESS RCMTCTAWNS SISHTWRELP
ADMSNHCFRV PRANKDEETF ILIDDTNAEV SHSLTAFEAE NDSSNRCATG ALLRVSDSQL
WRSPRASIAN PTTNDRLVPG AVVTKVSIPP GATEVVLCLQ SRATNRGLPA NLFALSGSGS
VELFRNSVAA INAPMPLPKI WELSARIQHQ FDADATGSYQ SFALPDLRHF YQAFLVQVVV
SKGSSVTSDS RKNVVLRFNV PNHHEEHFVA ANSDTPAVLS LILAMPVARR VPSSSLAVPT
LEMIRPAGYH VSLSITFDWP TIAMRVLALV GPVVFSTAAA VSVLPFVAMY PDGQLSGLLG
SASAFGATLS VTPVLFAVVG FSIQHQEETS FDALQHLGAP VSPLFVFLIA VLGIGLAVLV
SAVVRVEAFL FDRLFSIMRR SAIAQPSRFK FPLLISSTVL VFLVNFYYCM GVAFVGSFQL
IRLISYYRVP ASSNAQLRRF HNNLFTMVIL TAWPQLLAII AWIRHLQFSP SLPYSTIDLA
PICAHVALML TVLHSELLPI ARQSFKGLPI LQLVATATAF LLILLFASVN FASLQLTGAL
FASATVWLHG QF
//
