ID A0A0D3BSZ8_BRAOL Unreviewed; 526 AA.
AC A0A0D3BSZ8;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=tRNA(His) guanylyltransferase {ECO:0000256|ARBA:ARBA00012511};
DE EC=2.7.7.79 {ECO:0000256|ARBA:ARBA00012511};
GN Name=106337476 {ECO:0000313|EnsemblPlants:Bo4g049610.1};
OS Brassica oleracea var. oleracea.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=109376 {ECO:0000313|EnsemblPlants:Bo4g049610.1, ECO:0000313|Proteomes:UP000032141};
RN [1] {ECO:0000313|EnsemblPlants:Bo4g049610.1, ECO:0000313|Proteomes:UP000032141}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. TO1000 {ECO:0000313|Proteomes:UP000032141};
RX PubMed=24916971; DOI=10.1186/gb-2014-15-6-r77;
RA Parkin I.A., Koh C., Tang H., Robinson S.J., Kagale S., Clarke W.E.,
RA Town C.D., Nixon J., Krishnakumar V., Bidwell S.L., Denoeud F., Belcram H.,
RA Links M.G., Just J., Clarke C., Bender T., Huebert T., Mason A.S.,
RA Pires J.C., Barker G., Moore J., Walley P.G., Manoli S., Batley J.,
RA Edwards D., Nelson M.N., Wang X., Paterson A.H., King G., Bancroft I.,
RA Chalhoub B., Sharpe A.G.;
RT "Transcriptome and methylome profiling reveals relics of genome dominance
RT in the mesopolyploid Brassica oleracea.";
RL Genome Biol. 15:R77-R77(2014).
RN [2] {ECO:0000313|EnsemblPlants:Bo4g049610.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2015) to UniProtKB.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the tRNA(His) guanylyltransferase family.
CC {ECO:0000256|ARBA:ARBA00010113}.
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DR RefSeq; XP_013632043.1; XM_013776589.1.
DR AlphaFoldDB; A0A0D3BSZ8; -.
DR STRING; 109376.A0A0D3BSZ8; -.
DR EnsemblPlants; Bo4g049610.1; Bo4g049610.1; Bo4g049610.
DR GeneID; 106337476; -.
DR Gramene; Bo4g049610.1; Bo4g049610.1; Bo4g049610.
DR KEGG; boe:106337476; -.
DR eggNOG; KOG2721; Eukaryota.
DR HOGENOM; CLU_044271_4_0_1; -.
DR OMA; ILVWINA; -.
DR OrthoDB; 239198at2759; -.
DR Proteomes; UP000032141; Chromosome C4.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0008193; F:tRNA guanylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006400; P:tRNA modification; IEA:InterPro.
DR Gene3D; 3.30.70.3000; -; 2.
DR InterPro; IPR025845; Thg1_C_dom.
DR InterPro; IPR024956; tRNAHis_GuaTrfase_cat.
DR InterPro; IPR007537; tRNAHis_GuaTrfase_Thg1.
DR InterPro; IPR038469; tRNAHis_GuaTrfase_Thg1_sf.
DR PANTHER; PTHR12729:SF11; TRNA(HIS) GUANYLYLTRANSFERASE; 1.
DR PANTHER; PTHR12729; UNCHARACTERIZED; 1.
DR Pfam; PF04446; Thg1; 2.
DR Pfam; PF14413; Thg1C; 2.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000032141};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 6..133
FT /note="tRNAHis guanylyltransferase catalytic"
FT /evidence="ECO:0000259|Pfam:PF04446"
FT DOMAIN 139..230
FT /note="Thg1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14413"
FT DOMAIN 274..401
FT /note="tRNAHis guanylyltransferase catalytic"
FT /evidence="ECO:0000259|Pfam:PF04446"
FT DOMAIN 405..512
FT /note="Thg1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14413"
SQ SEQUENCE 526 AA; 61381 MW; ED30E9F8041FC4F9 CRC64;
MANSKYEYVK SFELEDEVML PNLILVRIDG RDFSRFSQVH EFEKPNDEAA LNLMNSCSSA
VLEEYPDIIF AYGYSDEYSF VFKKTSRFYQ RRASKILSLV ASFFASAYVT KWKEFFPQRK
LEYSPSFTSK VVSCASPEVL QAYLAWKQQD CHANNQYETC FWMLVKSGKT ISEAQEVLKD
TQKQQKNELL FQKFGINYKT LPELFRQGSC LFKKKVEETV KHDENGNPVK RLRRKAVLVH
SENIAGRSFW NEHPSLYNDL GHFTKDIGRV EPDFVRSFRF ESKLLPLTWV VVRIDGSHFH
RFSDVHEFEK PNDEQALKLM NSCAVAVLEE FEDIHFAYGV SDEYSFVLKR ESELYKRHSS
KIISAIASLF TSTYVIRWGD FFPHKELKYP PSFDGRAVCY PTYKILLDYL AWRQVDCHIN
NQYNTCFWML VKSGKTKTQS QDYLKGTQTR EKNELLSSQF GIEYNTLPLI FRMGSSVFRS
KEAVAVKNGV VVSGKKPKRE GEVVVDHCNI IERGFWEEHP HILSYS
//
