ID   A0A0D3CWC3_BRAOL        Unreviewed;       365 AA.
AC   A0A0D3CWC3;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=Auxin efflux carrier family protein {ECO:0008006|Google:ProtNLM};
OS   Brassica oleracea var. oleracea.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX   NCBI_TaxID=109376 {ECO:0000313|EnsemblPlants:Bo6g084870.1, ECO:0000313|Proteomes:UP000032141};
RN   [1] {ECO:0000313|EnsemblPlants:Bo6g084870.1, ECO:0000313|Proteomes:UP000032141}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=cv. TO1000 {ECO:0000313|Proteomes:UP000032141};
RX   PubMed=24916971; DOI=10.1186/gb-2014-15-6-r77;
RA   Parkin I.A., Koh C., Tang H., Robinson S.J., Kagale S., Clarke W.E.,
RA   Town C.D., Nixon J., Krishnakumar V., Bidwell S.L., Denoeud F., Belcram H.,
RA   Links M.G., Just J., Clarke C., Bender T., Huebert T., Mason A.S.,
RA   Pires J.C., Barker G., Moore J., Walley P.G., Manoli S., Batley J.,
RA   Edwards D., Nelson M.N., Wang X., Paterson A.H., King G., Bancroft I.,
RA   Chalhoub B., Sharpe A.G.;
RT   "Transcriptome and methylome profiling reveals relics of genome dominance
RT   in the mesopolyploid Brassica oleracea.";
RL   Genome Biol. 15:R77-R77(2014).
RN   [2] {ECO:0000313|EnsemblPlants:Bo6g084870.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (MAR-2015) to UniProtKB.
CC   -!- FUNCTION: Involved in cellular auxin homeostasis by regulating auxin
CC       metabolism. Regulates intracellular auxin accumulation at the
CC       endoplasmic reticulum and thus auxin availability for nuclear auxin
CC       signaling. {ECO:0000256|ARBA:ARBA00025100}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the auxin efflux carrier (TC 2.A.69.2) family.
CC       {ECO:0000256|ARBA:ARBA00025752}.
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DR   AlphaFoldDB; A0A0D3CWC3; -.
DR   STRING; 109376.A0A0D3CWC3; -.
DR   EnsemblPlants; Bo6g084870.1; Bo6g084870.1; Bo6g084870.
DR   Gramene; Bo6g084870.1; Bo6g084870.1; Bo6g084870.
DR   eggNOG; KOG2722; Eukaryota.
DR   HOGENOM; CLU_044945_0_0_1; -.
DR   OMA; GAVYIWI; -.
DR   Proteomes; UP000032141; Chromosome C6.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0080162; P:endoplasmic reticulum to cytosol auxin transport; IEA:InterPro.
DR   InterPro; IPR004776; Mem_transp_PIN-like.
DR   InterPro; IPR045033; PILS1/3/4/5/7.
DR   PANTHER; PTHR31651:SF19; PROTEIN PIN-LIKES 3-RELATED; 1.
DR   PANTHER; PTHR31651; TRANSPORTER; 1.
DR   Pfam; PF03547; Mem_trans; 2.
PE   3: Inferred from homology;
KW   Auxin signaling pathway {ECO:0000256|ARBA:ARBA00023294};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000032141};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        15..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        74..97
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        198..220
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        240..261
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        273..295
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        307..331
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        343..364
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   365 AA;  39956 MW;  0F4043349C140B52 CRC64;
     MLKLLHLFIT SSKPVVEILL ITSVGLYMAL DGVNLLGPDA RKYLNDIVFY VFNPSLVGSR
     LADSVTYESL VKMWFMPINL LLTFIIGSLL GWIVILITKP PSHLRGLIVG CCDADPENCN
     KYGMGYVALS MAMGSVYIWT YVYNLMRVLS NSPIETQPSI ESSCKVPLIS SKEEEEENHK
     VGRWDRFKRR MVSLSEKVNL STIFTPTTIA AIIALVIGLI NPVRKLIIGN VAPLGVLQDS
     VTLVGDGAIP ATTLIIGGNL LKGMRSSGMK RSSIIGVLVA RYILLPISGV LIVRGAYKLD
     LITSEPLYQF VLLIQYAVPP AMSLGTITQL FGAGESECSV VMLWAYGLAS VSLTAWPTFF
     MWLVA
//