ID A0A0D3DRT3_BRAOL Unreviewed; 654 AA.
AC A0A0D3DRT3;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Peptidase A1 domain-containing protein {ECO:0000259|PROSITE:PS51767};
OS Brassica oleracea var. oleracea.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=109376 {ECO:0000313|EnsemblPlants:Bo8g079410.1, ECO:0000313|Proteomes:UP000032141};
RN [1] {ECO:0000313|EnsemblPlants:Bo8g079410.1, ECO:0000313|Proteomes:UP000032141}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. TO1000 {ECO:0000313|Proteomes:UP000032141};
RX PubMed=24916971; DOI=10.1186/gb-2014-15-6-r77;
RA Parkin I.A., Koh C., Tang H., Robinson S.J., Kagale S., Clarke W.E.,
RA Town C.D., Nixon J., Krishnakumar V., Bidwell S.L., Denoeud F., Belcram H.,
RA Links M.G., Just J., Clarke C., Bender T., Huebert T., Mason A.S.,
RA Pires J.C., Barker G., Moore J., Walley P.G., Manoli S., Batley J.,
RA Edwards D., Nelson M.N., Wang X., Paterson A.H., King G., Bancroft I.,
RA Chalhoub B., Sharpe A.G.;
RT "Transcriptome and methylome profiling reveals relics of genome dominance
RT in the mesopolyploid Brassica oleracea.";
RL Genome Biol. 15:R77-R77(2014).
RN [2] {ECO:0000313|EnsemblPlants:Bo8g079410.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the peptidase A1 family.
CC {ECO:0000256|ARBA:ARBA00007447, ECO:0000256|RuleBase:RU000454}.
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DR AlphaFoldDB; A0A0D3DRT3; -.
DR STRING; 109376.A0A0D3DRT3; -.
DR EnsemblPlants; Bo8g079410.1; Bo8g079410.1; Bo8g079410.
DR Gramene; Bo8g079410.1; Bo8g079410.1; Bo8g079410.
DR eggNOG; KOG1339; Eukaryota.
DR HOGENOM; CLU_027606_0_0_1; -.
DR OMA; KCGNHQD; -.
DR Proteomes; UP000032141; Chromosome C8.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd05476; pepsin_A_like_plant; 1.
DR Gene3D; 2.40.70.10; Acid Proteases; 2.
DR InterPro; IPR001461; Aspartic_peptidase_A1.
DR InterPro; IPR001969; Aspartic_peptidase_AS.
DR InterPro; IPR034161; Pepsin-like_plant.
DR InterPro; IPR033121; PEPTIDASE_A1.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR032799; TAXi_C.
DR InterPro; IPR032861; TAXi_N.
DR PANTHER; PTHR13683; ASPARTYL PROTEASES; 1.
DR PANTHER; PTHR13683:SF824; PEPTIDASE A1 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF14541; TAXi_C; 1.
DR Pfam; PF14543; TAXi_N; 1.
DR PRINTS; PR00792; PEPSIN.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR PROSITE; PS00141; ASP_PROTEASE; 1.
DR PROSITE; PS51767; PEPTIDASE_A1; 1.
PE 3: Inferred from homology;
KW Aspartyl protease {ECO:0000256|ARBA:ARBA00022750,
KW ECO:0000256|RuleBase:RU000454}; Hydrolase {ECO:0000256|RuleBase:RU000454};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000256|RuleBase:RU000454};
KW Reference proteome {ECO:0000313|Proteomes:UP000032141};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..654
FT /note="Peptidase A1 domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002274619"
FT TRANSMEM 606..629
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 87..448
FT /note="Peptidase A1"
FT /evidence="ECO:0000259|PROSITE:PS51767"
FT REGION 463..484
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 105
FT /evidence="ECO:0000256|PIRSR:PIRSR601461-1"
FT ACT_SITE 323
FT /evidence="ECO:0000256|PIRSR:PIRSR601461-1"
SQ SEQUENCE 654 AA; 72275 MW; 47AD8009A8B8B5BB CRC64;
MALASIGAMF SLLIYLSLPC SNAAAENILH QSPPPADGSR SPMVFPLFLF QPNSSRSMSL
LHRKLHSKSL PHSRMRLYDD ILLNGYYTTR LWIGTPPQMF ALIVDSGSTV TYVPCSDCEQ
CGKHQDPKFQ PEMSTTYQPV KCNMDCHCDD DKEQCLYERE YAEHSSSKGV LGEDLISFGN
ESELTPHRAV FGCENVETGD LYSQRADGII GLGQGDLSLV DQLVDKGLIS NSFALCYGGM
DLGGGSMVLG GFAYPSDMMF TDSDPDRRYV PKGLSFVLIG EWIRFNTIDS PYYNIDLTGI
RVAGKDLLLD SRAFDGEHGV VLDSGTTYAY LPDAAFSAFE EALMREASPL KKIDGPDPNF
KDTCFHVAPS NDAAGLSTIF PSVEMVFKSG QSWLLSPENY LFRHSKVHGA YCLGVFPNGK
DHTTLLGGIV VRNTLVVYDR ENSKVGFWRT NCSELSDRLH IDDLAPPPAT LPSNDSNPTL
NTSSSLPGGE IQIGQINLDI QLTVNSSYLK PRMEELSKVL SKELDVKSSQ VYISNLTSKG
NNSLIRVVVV PTEPSSLFSN VTETSIVSRF TNHQIKLPDT FGNYELVSYT LEPSRKRARW
VMKNNIVVMA ILIVAVVVGL IAYGVWLMWK RKQASNPYIH VDEAIIAEQE LLPL
//
