ID A0A0D3LH76_9BACT Unreviewed; 539 AA.
AC A0A0D3LH76;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=D770_15960 {ECO:0000313|EMBL:AHM61446.1};
OS Flammeovirgaceae bacterium 311.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Flammeovirgaceae.
OX NCBI_TaxID=1257021 {ECO:0000313|EMBL:AHM61446.1, ECO:0000313|Proteomes:UP000064112};
RN [1] {ECO:0000313|EMBL:AHM61446.1, ECO:0000313|Proteomes:UP000064112}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=311 {ECO:0000313|EMBL:AHM61446.1,
RC ECO:0000313|Proteomes:UP000064112};
RA Fang C.;
RT "Complete bacteria genome obtained just from illumina data.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP004371; AHM61446.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D3LH76; -.
DR STRING; 1257021.D770_15960; -.
DR KEGG; fbt:D770_15960; -.
DR OrthoDB; 9124519at2; -.
DR Proteomes; UP000064112; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR42878:SF7; BACTERIOPHYTOCHROME; 1.
DR PANTHER; PTHR42878; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF13426; PAS_9; 2.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:AHM61446.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000064112};
KW Transferase {ECO:0000313|EMBL:AHM61446.1}.
FT DOMAIN 227..279
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 297..509
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 511..539
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 270..297
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 539 AA; 59904 MW; 9CA51FC89DE368AF CRC64;
MEQHIFYNQN IDALLNSLPD AVFIGDTKGI KRLNDQALHM MGLISEKDIP DSIVAFVKAF
NFRYLETNEK VIPGEGPFSE ALRGQRVVTE LRHTNHETGL PIFSRCAAAP ILENDQVTGI
IIILTDITER VIAGNKLQET LHALSYSTQE QEAVLDSIPD GVYMGNQSGI YKVNRPALEM
LGCNTARDVQ GQVEVIFSKL NARYADTKNP IPVSEDPFSR ALRGERVVQE IIITHLKTGK
DVYVRCAAAP VYLESKIIGA IAVNSDITDK VLAEQKLQKT LQELRKVNEE LEAFTYAVSH
DLKSPLGRIS GLASLLLISN ESQISDKDRY LLQLIVQSSE KLTELVSHLL NLGKIGQTEL
TYTKIDLTAL CKQVLENITP TKRSVKFSIA PNMYVWGDKT LMHSVMQNLL TNAAKYSSKN
PDAEVQVGTH EDDGFTLCYV RDNGVGFDMS EADKLFMPFK RLYTGTNFEG TGVGLSTVKR
IIERHEGKIW AESKPGEGAT FYFSLPNKVS KSGRHNHPLK LPEENPGTKI KKLSPQGLS
//
