ID A0A0D4C251_9MICC Unreviewed; 402 AA.
AC A0A0D4C251;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:AJT42451.1};
DE EC=2.3.1.9 {ECO:0000313|EMBL:AJT42451.1};
GN ORFNames=UM93_14825 {ECO:0000313|EMBL:AJT42451.1};
OS Psychromicrobium lacuslunae.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Psychromicrobium.
OX NCBI_TaxID=1618207 {ECO:0000313|EMBL:AJT42451.1, ECO:0000313|Proteomes:UP000061839};
RN [1] {ECO:0000313|EMBL:AJT42451.1, ECO:0000313|Proteomes:UP000061839}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IHBB 11108 {ECO:0000313|EMBL:AJT42451.1,
RC ECO:0000313|Proteomes:UP000061839};
RX PubMed=25908143;
RA Kiran S., Swarnkar M.K., Pal M., Thakur R., Tewari R., Singh A.K.,
RA Gulati A.;
RT "Complete Genome Sequencing of Protease-Producing Novel Arthrobacter sp.
RT Strain IHBB 11108 Using PacBio Single-Molecule Real-Time Sequencing
RT Technology.";
RL Genome Announc. 3:0-0(2015).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
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DR EMBL; CP011005; AJT42451.1; -; Genomic_DNA.
DR RefSeq; WP_045076308.1; NZ_CP011005.1.
DR AlphaFoldDB; A0A0D4C251; -.
DR STRING; 1618207.UM93_14825; -.
DR KEGG; ari:UM93_14825; -.
DR PATRIC; fig|1618207.4.peg.3019; -.
DR HOGENOM; CLU_031026_2_3_11; -.
DR OrthoDB; 1402717at2; -.
DR Proteomes; UP000061839; Chromosome.
DR GO; GO:0003985; F:acetyl-CoA C-acetyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR43365; BLR7806 PROTEIN; 1.
DR PANTHER; PTHR43365:SF1; STEROID 3-KETOACYL-COA THIOLASE FADA6; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00737; THIOLASE_2; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW ECO:0000313|EMBL:AJT42451.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000061839};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:AJT42451.1}.
FT DOMAIN 5..228
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 280..401
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 91
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 358
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 388
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 402 AA; 42116 MW; F0A7D4EE43DEC099 CRC64;
MPEAYIYDAV RTPRGKNKGG ALHGTKPVDL VVGLIKALEA RNPGLDPQAI DDIVLGVVSP
VGEQGGDIAR TAALVAELPE TVAGVQINRF CASGLEAVNL AAQKVASGFE DLVLAGGVES
MSRVPIGSDG GPYAQDPTTA YDAYFVPQGI GADLIATLEG FSREDVDAFA ARSQARAEQA
WQEGRFERSI VPVKDFNGVT LLDTDEHRRP GSSVESLGKL PASFAKLGEQ AGFDAVALQK
YHQLERINHV HGPGNSSGIV DGASLLVIGS AEIGERFGLT PRARIVSTAV TGSEPTIMLT
GPTPATQKAL KRAGLEVADI DLFELNEAFA AVVMKWQKDL NIPDEKVNVN GGAIALGHPL
GATGGMILGT LLDELERRDL KRGLATLCVG AGMGIATIIE RL
//
