ID A0A0D5M6Y2_9GAMM Unreviewed; 430 AA.
AC A0A0D5M6Y2;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=L-lysine 6-monooxygenase (NADPH) {ECO:0000313|EMBL:AJY51980.1};
DE EC=1.14.13.59 {ECO:0000313|EMBL:AJY51980.1};
GN ORFNames=KO116_03511 {ECO:0000313|EMBL:AJY51980.1};
OS Halomonas sp. KO116.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Halomonas.
OX NCBI_TaxID=1504981 {ECO:0000313|EMBL:AJY51980.1, ECO:0000313|Proteomes:UP000028645};
RN [1] {ECO:0000313|EMBL:AJY51980.1, ECO:0000313|Proteomes:UP000028645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KO116 {ECO:0000313|EMBL:AJY51980.1,
RC ECO:0000313|Proteomes:UP000028645};
RX PubMed=25953187;
RA O'Dell K.B., Woo H.L., Utturkar S., Klingeman D., Brown S.D., Hazen T.C.;
RT "Genome Sequence of Halomonas sp. Strain KO116, an Ionic Liquid-Tolerant
RT Marine Bacterium Isolated from a Lignin-Enriched Seawater Microcosm.";
RL Genome Announc. 3:0-0(2015).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- PATHWAY: Siderophore biosynthesis. {ECO:0000256|ARBA:ARBA00004924}.
CC -!- SIMILARITY: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-
CC oxygenase family. {ECO:0000256|ARBA:ARBA00007588}.
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DR EMBL; CP011052; AJY51980.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D5M6Y2; -.
DR STRING; 1504981.KO116_03511; -.
DR KEGG; hak:KO116_03511; -.
DR eggNOG; COG3486; Bacteria.
DR HOGENOM; CLU_020931_2_0_6; -.
DR OrthoDB; 7527071at2; -.
DR Proteomes; UP000028645; Chromosome.
DR GO; GO:0047091; F:L-lysine 6-monooxygenase (NADPH) activity; IEA:UniProtKB-EC.
DR GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR025700; Lys/Orn_oxygenase.
DR PANTHER; PTHR42802:SF1; L-ORNITHINE N(5)-MONOOXYGENASE; 1.
DR PANTHER; PTHR42802; MONOOXYGENASE; 1.
DR Pfam; PF13434; Lys_Orn_oxgnase; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
PE 3: Inferred from homology;
KW Monooxygenase {ECO:0000313|EMBL:AJY51980.1};
KW Oxidoreductase {ECO:0000313|EMBL:AJY51980.1}.
SQ SEQUENCE 430 AA; 48811 MW; 403C82EC94BABD97 CRC64;
MSNIYDFIAI GAGPANISLG AQAVERGLQP GKDFIILEKD TEVRWHPGML LPGSRLDTHF
VKDLVAMVNP MSRFTFLNFL VQHKRLEDFL NCGRSTPYRR DFDEYLRWVA NALGNGIRTG
SCVSEIKQDG SDLYLVKYLA RDGSFQEVRT RDVVLGVGGQ PKYPFGLNGS DSRIIHSADF
LTKIAKLKDF KENNSVLVVG AGQSAAELVK YLLGATKNSI DVAISDFGFG IKEGTSFMNE
SYNGEFVDRF FDMPIETRKW FVNQRKNMNY GVVDEAIIDG LYNDYYYDKH FERRSISFLQ
FCRVVKIEAE QNQPIQVQFF NHESGEKFAN HYNYVVLATG YEFSEPSRLL QDIYASLAFE
DDSFLMERDY SIQQKHGIRS GRVYMNGNVS KTHGPAQDVL SVIAHRSRDI LQSIMSRTRV
KTREAAKATG
//
