ID A0A0D6P8Q8_9PROT Unreviewed; 609 AA.
AC A0A0D6P8Q8;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Chloride channel protein {ECO:0000313|EMBL:GAN78067.1};
GN ORFNames=Asru_0603_05 {ECO:0000313|EMBL:GAN78067.1};
OS Acidisphaera rubrifaciens HS-AP3.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Acidisphaera.
OX NCBI_TaxID=1231350 {ECO:0000313|EMBL:GAN78067.1, ECO:0000313|Proteomes:UP000032680};
RN [1] {ECO:0000313|EMBL:GAN78067.1, ECO:0000313|Proteomes:UP000032680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HS-AP3 {ECO:0000313|EMBL:GAN78067.1,
RC ECO:0000313|Proteomes:UP000032680};
RA Azuma Y., Higashiura N., Hirakawa H., Matsushita K.;
RT "Whole genome sequence of Acidisphaera rubrifaciens HS-AP3.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAN78067.1}.
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DR EMBL; BANB01000603; GAN78067.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D6P8Q8; -.
DR OrthoDB; 9811720at2; -.
DR Proteomes; UP000032680; Unassembled WGS sequence.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd02205; CBS_pair_SF; 1.
DR CDD; cd00400; Voltage_gated_ClC; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SMART; SM00116; CBS; 2.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 2.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000032680};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 30..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 213..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 350..369
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 376..401
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 407..428
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 462..521
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 526..584
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT REGION 585..609
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 609 AA; 63086 MW; 47F1FAE01F115C18 CRC64;
MSYHDMNRQD CSVTPPRFAR PGDFTTDTRV LLLAAMAVVV GTGGVAGAWV LLRLIALFTN
LAYYGAASFA FVGPAHNALG WWAALVPAAG GLLIGLMARY GSEKIRGHGI PEAIEAILIG
GSRMDVRVAI LKPISSALSI GTGGPFGAEG PIIMTGGALG SLFAQRFAMT AAERKVLLVA
GAAAGMAAVF GTPIAAVLLA VELLLFEWKP RSFIPVVVAC VTAALERGVV LAPVPLFPHL
GAVANDGLHA LGWVALGIAC GLGSGLLTAM VYGTEDSFGH LPIHWMWWPA IGGLVVGVGG
VVEPSALGVG YGNIAQLLTG SMVGRAALLL LVVKSVIWAV SLGSGTSGGV LAPLLMMGGA
LGALAAPWLP GAEPGFWAMI GMAAMMGGTM RAPLTAALFA VELTGDFAAI LPLFAACATA
YAVTVLLLRR SILTEKVARR GHHIVREYLV DPYALVSVRD VMANPVETLD SSVPAAEAAA
FFTGPGPRHK AYPVVDRDGR LAGMISRADA LAWLRDPPSG LLGDVVAQVP ASIAYPDEPL
AAVMDRMVQD DTGRIPVIAR EDGRVVGLLA RKDLLRVRAR MVDEEHRREG PSRAVRPVVS
AEAAAGAGE
//
