ID A0A0D8PL17_9GAMM Unreviewed; 859 AA.
AC A0A0D8PL17;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Chaperone protein ClpB {ECO:0000256|ARBA:ARBA00017574, ECO:0000256|RuleBase:RU362034};
GN Name=clpB {ECO:0000256|RuleBase:RU362034};
GN ORFNames=C9I88_19485 {ECO:0000313|EMBL:PSV88872.1};
OS Photobacterium iliopiscarium.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Photobacterium.
OX NCBI_TaxID=56192 {ECO:0000313|EMBL:PSV88872.1, ECO:0000313|Proteomes:UP000241954};
RN [1] {ECO:0000313|EMBL:PSV88872.1, ECO:0000313|Proteomes:UP000241954}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCIMB 13481 {ECO:0000313|EMBL:PSV88872.1,
RC ECO:0000313|Proteomes:UP000241954};
RA Butler K.;
RT "Whole genome sequencing of Histamine producing bacteria.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Part of a stress-induced multi-chaperone system, it is
CC involved in the recovery of the cell from heat-induced damage, in
CC cooperation with DnaK, DnaJ and GrpE. {ECO:0000256|RuleBase:RU362034}.
CC -!- SUBUNIT: Homohexamer. The oligomerization is ATP-dependent.
CC {ECO:0000256|ARBA:ARBA00026057}.
CC -!- SUBUNIT: Homohexamer; The oligomerization is ATP-dependent.
CC {ECO:0000256|RuleBase:RU362034}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU362034}.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675, ECO:0000256|RuleBase:RU004432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PSV88872.1}.
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DR EMBL; PYLW01000037; PSV88872.1; -; Genomic_DNA.
DR RefSeq; WP_045038604.1; NZ_PYOP01000043.1.
DR AlphaFoldDB; A0A0D8PL17; -.
DR STRING; 56192.UB38_10475; -.
DR GeneID; 70040847; -.
DR OrthoDB; 9803641at2; -.
DR Proteomes; UP000241954; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0042026; P:protein refolding; IEA:UniProtKB-UniRule.
DR GO; GO:0009408; P:response to heat; IEA:UniProtKB-UniRule.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR017730; Chaperonin_ClpB.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR03346; chaperone_ClpB; 1.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF18; HEAT SHOCK PROTEIN 78, MITOCHONDRIAL; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 2.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|RuleBase:RU362034};
KW Cytoplasm {ECO:0000256|RuleBase:RU362034};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}; Stress response {ECO:0000256|RuleBase:RU362034}.
FT DOMAIN 3..147
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT COILED 413..462
FT /evidence="ECO:0000256|RuleBase:RU362034"
SQ SEQUENCE 859 AA; 96038 MW; E219AFADC999D53C CRC64;
MRLDRFTSKF QAAISDAQSL ALGRDHQYIE PAHLMVALLN QEGSTVRPLL TLLNVDSTQL
RSRLGEILER IPKVTGIGGE VQLSNSMGTL LNMCDKLAQK RNDKFISSEL FILAVVDNDK
GPLGDLLREL GLKADQIGKA IDQIRGGQKV DDQNAEENRQ ALSKYTIDLT ERAEQGRLDP
VIGRDDEIRR TIQVLQRRTK NNPVIIGEPG VGKTAIVEGL AQRIVNGEVP EGLRDKRVLS
LDMGSLIAGA KFRGEFEERL KAVLNELSQE DGRIILFIDE IHTMVGAGKG EGSMDAGNML
KPALARGDLH CVGATTLNEY RQYLEKDAAL ERRFQKVLVD EPSVEDTIAI LRGLKERYEL
HHHVEITDPA IVAAATLSHR YISDRQLPDK AIDLIDEAAS SIRMQIDSKP ESMDRLERRI
IQLKIEQQAL EKESDDASQK RLSNLLEELD IKEREYSELE EVWNAEKASL SGTQHIKTEL
EQARTDVEIA RRAGDLNRMS ELQYGRIPEL EKQLDLAAQA EMQDMTLLKN KVTDVEIADV
LSKATGIPVA KMLEGERDKL LRMEDELHNR VIGQEEAVEA VANAIRRSRA GLSDPQRPIG
SFLFLGPTGV GKTELCKSLA NFMFDSEDAM VRIDMSEFME KHSVARLVGA PPGYVGYEEG
GYLTEAVRRR PYSVILLDEV EKAHPDVFNI LLQVLDDGRL TDGQGRTVDF RNTVIIMTSN
LGSDRIQEHF GSLDYEGIKA LVMEVVGQHF RPEFINRVDE TVVFHPLGKD NIKHIASIQL
ARLEKRLAEK DFQLEVEESA LELISDAGFD PVFGARPLKR AIQQYIENPL AQDLLSGKFM
PGKPIVLSVE DDKIVAKQA
//
