ID A0A0D8Y335_DICVI Unreviewed; 1036 AA.
AC A0A0D8Y335;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Pre-mRNA-processing factor 6 {ECO:0000256|ARBA:ARBA00020235};
DE AltName: Full=PRP6 homolog {ECO:0000256|ARBA:ARBA00032140};
DE AltName: Full=U5 snRNP-associated 102 kDa protein {ECO:0000256|ARBA:ARBA00031070};
GN ORFNames=DICVIV_03440 {ECO:0000313|EMBL:KJH50429.1};
OS Dictyocaulus viviparus (Bovine lungworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae; Dictyocaulus.
OX NCBI_TaxID=29172 {ECO:0000313|EMBL:KJH50429.1, ECO:0000313|Proteomes:UP000053766};
RN [1] {ECO:0000313|EMBL:KJH50429.1, ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|EMBL:KJH50429.1,
RC ECO:0000313|Proteomes:UP000053766};
RA Mitreva M.;
RT "Draft genome of the bovine lungworm Dictyocaulus viviparus.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|Proteomes:UP000053766};
RX PubMed=26856411; DOI=10.1038/srep20316;
RA McNulty S.N., Strube C., Rosa B.A., Martin J.C., Tyagi R., Choi Y.J.,
RA Wang Q., Hallsworth Pepin K., Zhang X., Ozersky P., Wilson R.K.,
RA Sternberg P.W., Gasser R.B., Mitreva M.;
RT "Dictyocaulus viviparus genome, variome and transcriptome elucidate
RT lungworm biology and support future intervention.";
RL Sci. Rep. 6:20316-20316(2016).
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DR EMBL; KN716206; KJH50429.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D8Y335; -.
DR STRING; 29172.A0A0D8Y335; -.
DR Proteomes; UP000053766; Unassembled WGS sequence.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 4.
DR InterPro; IPR003107; HAT.
DR InterPro; IPR010491; PRP1_N.
DR InterPro; IPR045075; Syf1-like.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR11246; PRE-MRNA SPLICING FACTOR; 1.
DR PANTHER; PTHR11246:SF1; PRE-MRNA-PROCESSING FACTOR 6; 1.
DR Pfam; PF06424; PRP1_N; 1.
DR Pfam; PF14559; TPR_19; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00386; HAT; 13.
DR SMART; SM00028; TPR; 4.
DR SUPFAM; SSF48452; TPR-like; 4.
DR PROSITE; PS50005; TPR; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000053766};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..1036
FT /note="Pre-mRNA-processing factor 6"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002336342"
FT DOMAIN 19..158
FT /note="PRP1 splicing factor N-terminal"
FT /evidence="ECO:0000259|Pfam:PF06424"
FT REPEAT 792..825
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 936..969
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 24..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 110..137
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 46..61
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1036 AA; 117812 MW; 8B2E13ABE78E87C1 CRC64;
MKTKHVMLVL TMLNLSLLGA TGFTTRSDIG PAREATDVPE TGTGPPSKKP KEDVKDDSEE
ALNDNNYDEF EGYAGSLFAK DPYDKEDEEA DEVYLAVETR IDERRKDYRE KKYKEAIEKY
RKERPKIQQE FSDLKRQLSE VTEDEWVAIP EVGDSRNKAK RNPRAEKFTP VPDSLIAMSM
TYGETTSTLD SRVQSGMTTP FGSGFQSTFG GMQSSLGGWK TGIHSGISTG HDLDLIKIGQ
ARNKIMDIKL NQVSDSVSGQ TVVDPKGYLT DLQSMIPQYG GDINDVKKAR MLLKSVRETN
PKHPPAWIAS ARLEEVVGKL QVARHLIMEG CEKNKKSEDM WLEAVSSMKM FSLYIVVKAR
MLLKSVRETN PKHPPAWIAS ARLEEVVGKL QVARHLIMEG CEKNKKSEDM WLEAVRLHPP
ETAKAIVANA VHAMPHSVRI WMKTAEIEAD LKAKKKAYFY SIFLEFRKGV FRKALEQIPT
SVRLWKAAIE LEEPDDARVL LTRAVECCSS STELWLALAR LETYENARKV LNKAREHIPT
DRQIWLCAAR LEETRGQKDM VDRIVQKALT SLTANMVELN REHWMKDAVD AERAGCTLTC
QAIIRHVIGA GVEDEDKKTT WLEDADSFAK QGALACARAV YAHALKNVEK RKGIWLAAAH
FEKTHGTTGI WFSEEYEALL ADATSSCPQV EVLWLMYAKS RWLHGDVTGA REILAKAFEH
NANSEGIWMA AVKLESENNE FARARRLLEK ARRNAPSARI WMKSARLEWC LGDLNRAKEL
IKEGLERYPD FAKLYMMLGQ ISLQESEYDE ARKIFTDGIK KCPGAVPLWL LLSRLEESQK
QITKARSDLE KASLICLIFL SEYARIRNPR NEELWLEAVR LEMRGGLREL ASERLARALQ
ECEGSGRLWA EAIWMEERHG RRAKSVDALK RCEHNPHVLV AAARLFWAER KVKKAREWFQ
RAINVDPDNG DAYAHCYKFE MLLGTEDEQE RVLKKCEEAE PRHGELWVSV SKDPKHWRKQ
TGDILKTVVA SIPIPS
//
