ID   A0A0D8Y7Y4_DICVI        Unreviewed;      1063 AA.
AC   A0A0D8Y7Y4;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   RecName: Full=Calponin-homology (CH) domain-containing protein {ECO:0000259|PROSITE:PS50021};
GN   ORFNames=DICVIV_00837 {ECO:0000313|EMBL:KJH52968.1};
OS   Dictyocaulus viviparus (Bovine lungworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae; Dictyocaulus.
OX   NCBI_TaxID=29172 {ECO:0000313|EMBL:KJH52968.1, ECO:0000313|Proteomes:UP000053766};
RN   [1] {ECO:0000313|EMBL:KJH52968.1, ECO:0000313|Proteomes:UP000053766}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HannoverDv2000 {ECO:0000313|EMBL:KJH52968.1,
RC   ECO:0000313|Proteomes:UP000053766};
RA   Mitreva M.;
RT   "Draft genome of the bovine lungworm Dictyocaulus viviparus.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000053766}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HannoverDv2000 {ECO:0000313|Proteomes:UP000053766};
RX   PubMed=26856411; DOI=10.1038/srep20316;
RA   McNulty S.N., Strube C., Rosa B.A., Martin J.C., Tyagi R., Choi Y.J.,
RA   Wang Q., Hallsworth Pepin K., Zhang X., Ozersky P., Wilson R.K.,
RA   Sternberg P.W., Gasser R.B., Mitreva M.;
RT   "Dictyocaulus viviparus genome, variome and transcriptome elucidate
RT   lungworm biology and support future intervention.";
RL   Sci. Rep. 6:20316-20316(2016).
CC   -!- SUBCELLULAR LOCATION: Nucleus outer membrane
CC       {ECO:0000256|ARBA:ARBA00004605}; Single-pass type IV membrane protein
CC       {ECO:0000256|ARBA:ARBA00004605}; Cytoplasmic side
CC       {ECO:0000256|ARBA:ARBA00004605}.
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DR   EMBL; KN716157; KJH52968.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0D8Y7Y4; -.
DR   STRING; 29172.A0A0D8Y7Y4; -.
DR   Proteomes; UP000053766; Unassembled WGS sequence.
DR   GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR   InterPro; IPR001589; Actinin_actin-bd_CS.
DR   InterPro; IPR039906; Anc-1/SYNE1/2-like.
DR   InterPro; IPR001715; CH_dom.
DR   InterPro; IPR036872; CH_dom_sf.
DR   PANTHER; PTHR21524:SF5; KLARSICHT PROTEIN; 1.
DR   PANTHER; PTHR21524; SPECTRIN REPEAT CONTAINING NUCLEAR ENVELOPE PROTEIN 2; 1.
DR   Pfam; PF00307; CH; 2.
DR   SMART; SM00033; CH; 1.
DR   SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR   PROSITE; PS00020; ACTININ_2; 1.
DR   PROSITE; PS50021; CH; 2.
PE   4: Predicted;
KW   Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053766};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          1..98
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000259|PROSITE:PS50021"
FT   DOMAIN          160..265
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000259|PROSITE:PS50021"
SQ   SEQUENCE   1063 AA;  123677 MW;  9AD149E7E336D57B CRC64;
     MTFNVRASSF WLYYPLDETP SLLFYRITFV IRQKLLKSPQ ICRPRVPKRA HHISNLTTAL
     TVLRRRGLEL VNNNASDIAD GNPRIILGLI WQIILHFQIE TNVALLREWG WGSIDVQSSR
     EHIHSRSLSS PMNSYTTSSI SSVPSTSTDS PKISMRLMKS SIEQVMIRWI NNEVAQRVNM
     RVENMDHDWK DGVMFNALVF RWKPDVIDME KVRTVDAKTN LENAFEMASK HLGIKRLLEV
     EDVLQAKPDK RSIITYVSQF IRAFGKSPPV AEECDVHSEF VEWLSKAYRL DLVNNDHQAY
     FRILHEFVEY RCIFNTIMAT KFNFTLEELS EIQTRWETLQ RNLEAAASVV EKRLPKPYSS
     LSDWTAQGQS IISTPLNLPS ENPQKCLAIL QKMISDHNRH FVDLSAKMDE LNTALEHDRV
     SGRSVAPEYV EPLRLRMKAL AAEVPMKIAT LKILYSYYRC LAYVDDLECK MELWRSPESL
     QLLDRWITEY DLVEIENPHM KCNNYIEMLK KELSSGTCVK VNGEGMVKKC CDRSEEVLKS
     FGSLKEELIK LRILWTEWEN ELKRLEAIAI EGGKMHVNTL KEETEAIRLL ESKFDTLVPL
     LSVAARLYCN RRMEMIKENV KQLNKFAASS RLVKLIPSTS QSHHRGIHNV NTLEARIKEI
     NNILKMQTVG CVENELQEKC KKMDLKRELT VLQNAKPRMC LIEHYLDELQ KLLASKDANS
     YDRAQDVWNQ LEREINALNS SEISHYVDCK NYEGLSSWCA AKIRGEVVNT FKISEEQPPV
     NKEYVKEVIN RVELILARRE ANDDEIRASI NDMADCETVL TGWSNKKLDG LRTLWNAKQI
     EFQLWQTYME RVRQIADILE QRRTCDSQTM DEIKRIEKIC EQISLTDLNR PLRSAVNELR
     DRAERVLKER LDSLRMSGEE DCFVAHDIVQ AYPNSHWINI TKHLKTYDLM KIGEELVAFC
     PQLNERSIET RTTLFGKMEL FRRLQNYYDT VKYLRNQNDT WNVTTLSEVP VILSELKRLL
     ILCDSDLYND GLQLRADLIA INGSFFQLEF DRVNEKSVAI PFF
//