ID A0A0D9QEH4_PLAFR Unreviewed; 1473 AA.
AC A0A0D9QEH4;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Obg family GTPase CgtA {ECO:0000313|EMBL:KJP85465.1};
GN ORFNames=AK88_04904 {ECO:0000313|EMBL:KJP85465.1};
OS Plasmodium fragile.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=5857 {ECO:0000313|EMBL:KJP85465.1, ECO:0000313|Proteomes:UP000054561};
RN [1] {ECO:0000313|EMBL:KJP85465.1, ECO:0000313|Proteomes:UP000054561}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=nilgiri {ECO:0000313|Proteomes:UP000054561};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Duraisingh M., Young S.K., Zeng Q., Gargeya S., Abouelleil A.,
RA Alvarado L., Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., Pearson M.,
RA Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium fragile nilgiri.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KQ001724; KJP85465.1; -; Genomic_DNA.
DR RefSeq; XP_012337931.1; XM_012482508.1.
DR EnsemblProtists; KJP85465; KJP85465; AK88_04904.
DR GeneID; 24270218; -.
DR VEuPathDB; PlasmoDB:AK88_04904; -.
DR OMA; FHELEDV; -.
DR OrthoDB; 232786at2759; -.
DR Proteomes; UP000054561; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.40.180; -; 1.
DR Gene3D; 3.30.300.350; GTP-binding protein OBG, C-terminal domain; 1.
DR Gene3D; 2.70.210.12; GTP1/OBG domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR006073; GTP-bd.
DR InterPro; IPR036346; GTP-bd_prot_GTP1/OBG_C_sf.
DR InterPro; IPR006169; GTP1_OBG_dom.
DR InterPro; IPR036726; GTP1_OBG_dom_sf.
DR InterPro; IPR003891; Initiation_fac_eIF4g_MI.
DR InterPro; IPR045086; OBG_GTPase.
DR InterPro; IPR015349; OCT_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR03595; Obg_CgtA_exten; 1.
DR PANTHER; PTHR11702; DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED; 1.
DR PANTHER; PTHR11702:SF44; GTP-BINDING PROTEIN OBGC, CHLOROPLASTIC; 1.
DR Pfam; PF09269; DUF1967; 1.
DR Pfam; PF01018; GTP1_OBG; 1.
DR Pfam; PF01926; MMR_HSR1; 1.
DR PRINTS; PR00326; GTP1OBG.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF102741; Obg GTP-binding protein C-terminal domain; 1.
DR SUPFAM; SSF82051; Obg GTP-binding protein N-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51366; MI; 1.
DR PROSITE; PS51883; OBG; 1.
DR PROSITE; PS51881; OCT; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134}.
FT DOMAIN 676..793
FT /note="MI"
FT /evidence="ECO:0000259|PROSITE:PS51366"
FT DOMAIN 968..1126
FT /note="Obg"
FT /evidence="ECO:0000259|PROSITE:PS51883"
FT DOMAIN 1387..1472
FT /note="OCT"
FT /evidence="ECO:0000259|PROSITE:PS51881"
FT REGION 18..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 149..251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 374..399
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1180..1206
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 28..44
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..64
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 156..193
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1180..1205
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1473 AA; 169752 MW; F7C8D1C80C99A8F2 CRC64;
MRNRRELRKL ARIQKKERKL LFSKKKKNYQ GKNVSTINTP DESLEEGSTK QDEGNMKRKR
KYSEGNNLSG PLKKQKKKSH SKIKYDISAE QEKDNQLLSY LSKKLKLNNT HDGKNNEEKV
CKQLEKDGFD SNLLKLTDII FGEFQKSYKK KCKKGKNALR GDDDTLGRSS EEEEVLSEGQ
DDATSEKDTD KKEKKKERRK KKKKSHTGVM ENEADEDAEE AEGMLSPRGK ANKGKKAAKA
EKKKKKKAPN YPEEAKKIEK FLMISLNKTS EFNIKSIIQD LCKYFHELED VKLKVMFNDA
LTKIACNHFN NVNATDIHIC ICVVIICVLN NLVYRNLLKD FLKVLTGVFK QLYEDNRDLM
RKIERENELS SVVAPNHDNL QNGNENGGPN GQNEPLTRSS EANQCDIPTE GYTNNAKQSS
SQNNFIVTQE EQEKYQNFKI ILRNILKSFC LFYALSYLDF DCITDIINLL CEDISISSVD
NIIIILKISG MKLKSEDISH LNYITEYLKK QIDNYIVSNN IYVERSKLRF LIKDIEDLKN
GTMKFHFLNK FEFLFSILNE FENKYNFRGK MVSFSFLKNF KSAECAIRQG GKKGTKKRKS
RENEEMEKRD MCTNGTLVEM EAKTDDNDNN PVGDEEEKSV KNKFCKLNYL MAGEEEEYFN
ESYFGKLLKK YKIQGILPKK IFLIIKNSLD VNECVHNLSL ILKKKKNIPH VIQTIIQTLL
YEKKYKVAYA KMLRNISNVK SRIFLFSLKT VFINYLKNIN NYDLKQVLFL SKLFTFLFKE
KLLNFHIFKF IEMDPHEIEG KKKQKHCNLF FFLKTVFILI SLHDKSGDLN TNSELWCHIM
ETTQSGHLGK STISAFKAIV KKYIFDEADN IVRVYPNFKI RYAEKFFAFL EVEKEGEIRT
LRRNMHIGFT ILFLMIFQKT AVLYNFPSKC GRQNTVFVNS SIKCKEGEKR SSRTANKLHC
MKKQIKKNQF HDRCVINIKG GNGGDGICCF TTFSQKKNKK YASGGRGGKG GNVYLIGDKK
IDNFLSLKLK SSYYAGNGGK GLNNNQSGQN GKDECINIPV NTIIYDEDKK FVNFIHLNGQ
KVLVALGGKG GKGNYSYRTK SLKIPFVCQF GEKTKEKKIF LKKIFFTDFG IIGYPNVGKS
TLLNRITNAN VKIANYSYTS KFPNLGIFRR DQNSVEEDNL VEGKERDEGV LEENNPVQEK
DEGDEDIWGG NCEEAEDLLD GETDSTDDTA HEGGEKNMAK NNYTVIDFPG IIKNLDKKAQ
NISYKYLEHL KYCKILIYMF DINSSIDVLL ETYRNIKDVL VQYDAIFKGK KEVVLLNKID
IYKENKDNVS KLINHLRENL KIENIFCISA LTGENAVDAI NEIVSNINNE NTISEFLKSL
PEPIDIAKIE DSDNFRPSQF EIYKYKENIF IVKGTYIENQ ANIFNFSKSD TSKIFAKILD
QLNINVKLKN VGAREGDTII ISNYSYEFSL EGD
//
