ID A0A0D9QID1_PLAFR Unreviewed; 944 AA.
AC A0A0D9QID1;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 13-SEP-2023, entry version 38.
DE RecName: Full=Pre-mRNA-splicing factor CEF1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=AK88_03758 {ECO:0000313|EMBL:KJP86562.1};
OS Plasmodium fragile.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=5857 {ECO:0000313|EMBL:KJP86562.1, ECO:0000313|Proteomes:UP000054561};
RN [1] {ECO:0000313|EMBL:KJP86562.1, ECO:0000313|Proteomes:UP000054561}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=nilgiri {ECO:0000313|Proteomes:UP000054561};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Duraisingh M., Young S.K., Zeng Q., Gargeya S., Abouelleil A.,
RA Alvarado L., Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., Pearson M.,
RA Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium fragile nilgiri.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the CEF1 family.
CC {ECO:0000256|ARBA:ARBA00010506}.
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DR EMBL; KQ001690; KJP86562.1; -; Genomic_DNA.
DR RefSeq; XP_012336791.1; XM_012481368.1.
DR AlphaFoldDB; A0A0D9QID1; -.
DR EnsemblProtists; KJP86562; KJP86562; AK88_03758.
DR GeneID; 24269072; -.
DR VEuPathDB; PlasmoDB:AK88_03758; -.
DR OMA; CLDHYEY; -.
DR OrthoDB; 131128at2759; -.
DR Proteomes; UP000054561; Unassembled WGS sequence.
DR GO; GO:0000974; C:Prp19 complex; IEA:InterPro.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR CDD; cd00167; SANT; 1.
DR CDD; cd11659; SANT_CDC5_II; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR InterPro; IPR047242; CDC5L/Cef1.
DR InterPro; IPR021786; Cdc5p/Cef1_C.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR047240; SANT_CDC5L_II.
DR PANTHER; PTHR45885; CELL DIVISION CYCLE 5-LIKE PROTEIN; 1.
DR PANTHER; PTHR45885:SF1; CELL DIVISION CYCLE 5-LIKE PROTEIN; 1.
DR Pfam; PF11831; Myb_Cef; 1.
DR Pfam; PF13921; Myb_DNA-bind_6; 1.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS51294; HTH_MYB; 2.
DR PROSITE; PS50090; MYB_LIKE; 2.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT DOMAIN 2..53
FT /note="HTH myb-type"
FT /evidence="ECO:0000259|PROSITE:PS51294"
FT DOMAIN 2..53
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT DOMAIN 54..107
FT /note="HTH myb-type"
FT /evidence="ECO:0000259|PROSITE:PS51294"
FT DOMAIN 54..103
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT REGION 113..140
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 262..285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 422..469
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 719..747
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 897..930
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 432..446
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..464
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 722..736
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 906..923
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 944 AA; 109417 MW; 616B89E9B48125EC CRC64;
MRIQIKGGIW KNCEDEVLKA AVMKYGLNNW SRVASLLVRK SAKQCKARWY EWLDPSVKKT
EWSKEEEEKL LHLAKLFPTQ WRTIAPIVGR TAKQCLDHYE YLLDEAEGKV YDKNKNPRQL
RPGEIDPAPE TKPAKADPVD MDEDEKEMLA EAKARLANTK GKKAKRKARE KQLEQARRLA
LLQKKRELKA AGIVSTTTGY KKNDKHRIDH VKEILFERKP AKGFFDVSEE QSLTHFEDKK
EKKFKSIKSM DVENINDVAM GGPYDDPGAD ASGKKASSKG KRNNEEKDLL SAIENYDKQY
NELSHLRKRV RLNLPEPILN ENELEEIIQI NKEASSFNEI IKEHNEKNNQ NGLGISNILP
SVTSSPFILN DRDKFSSIGT NFYSKSIAFS SKLDFGIQQA AQSIIARNIN EPIIGVRDSI
QMQQQVKPHM KQQAKQQEKQ HQGDEAEEEL REDDGDDEEE YSPMLHDEPE NIAQNVQAVR
EEIESGKTLN QNENATKERN HLKDKIINDI RSNQKNASLY AHSLISYKIG KNENSVCDRN
TLLSELYDED YEEKIDRAKL LIKSSLAHLP KESNVIELQI PEDLNEQESQ INYEHVQVEK
DMQDIAKEKK MEQLKKEQER FNSQNKVIRW NLPRPYFLPQ MNLTPSIPLP TTPEDATSKE
VENAVRNEML LLIKNDMFNY PMKNGTPIQK RVHLYDVDKT YMRMALEFVQ DELQKITPQQ
DKGGKLHGEE ANGVKSSNEE NDTNEANTLP TLQPRKVEAW AKINEQVLYC PAKKAYTFIE
RMSERDIKES YKHTCEKLNS FIQKNVELYK KTENKYDIYT KGYEQKIKGY KKSFDSQFNT
YINYLNEKDA LSALHEREKV HARERIRQER EENKKEIEYH KSLQRLYVEL LEDNKRLRHG
DPQPDQAGPN GTTPDQAGPN GTKPEQSAVA PRANRFFPFF FCTI
//
