ID A0A0D9RFY8_CHLSB Unreviewed; 426 AA.
AC A0A0D9RFY8;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Potassium channel tetramerization domain containing 18 {ECO:0000313|Ensembl:ENSCSAP00000007527.1};
GN Name=KCTD18 {ECO:0000313|Ensembl:ENSCSAP00000007527.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000007527.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000007527.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000007527.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AQIB01007539; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007963974.1; XM_007965783.1.
DR RefSeq; XP_007963975.1; XM_007965784.1.
DR RefSeq; XP_007963976.1; XM_007965785.1.
DR AlphaFoldDB; A0A0D9RFY8; -.
DR STRING; 60711.ENSCSAP00000007527; -.
DR Ensembl; ENSCSAT00000009411.1; ENSCSAP00000007527.1; ENSCSAG00000011318.1.
DR GeneID; 103217610; -.
DR KEGG; csab:103217610; -.
DR CTD; 130535; -.
DR eggNOG; KOG2723; Eukaryota.
DR GeneTree; ENSGT00530000064234; -.
DR OMA; CKAGPKP; -.
DR BioGRID-ORCS; 103217610; 0 hits in 9 CRISPR screens.
DR Proteomes; UP000029965; Chromosome 10.
DR Bgee; ENSCSAG00000011318; Expressed in adrenal cortex and 7 other cell types or tissues.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR CDD; cd18372; BTB_POZ_KCTD18; 1.
DR InterPro; IPR045704; KCTD18_C.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR PANTHER; PTHR14499:SF4; BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD18; 1.
DR PANTHER; PTHR14499; POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING; 1.
DR Pfam; PF02214; BTB_2; 1.
DR Pfam; PF19321; KCTD18_C; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000029965}.
FT DOMAIN 14..98
FT /note="Potassium channel tetramerisation-type BTB"
FT /evidence="ECO:0000259|Pfam:PF02214"
FT DOMAIN 114..425
FT /note="BTB/POZ"
FT /evidence="ECO:0000259|Pfam:PF19321"
FT REGION 314..371
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 387..426
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 314..333
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 387..404
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 426 AA; 46765 MW; 42F428981E1A0B88 CRC64;
MEGHKAGEEV LDVLRLNVGG CIYTARRESL CRFKDSMLAS MFSGRFPLKT DESGACVIDR
DGRLFKYLLD YLHGEVQIPT DEQTRIALQE EADYFGIPYP YSLSDHLANE METYSLRSNI
ELKKALTDFC DSYGLVCNKP TVWVLHYLNT SGASCESRII GVYATKTDGT DAIDKQLGGR
IHSKSIFKRE AGNNVQYIWS YYSVAELKKM MDAFDAWEGK GVSYWRVPHE LIECWTLEER
PLLGSLHHMA PIRKRRLITF NEEDEGVNCK TGPKPVRFLG PSTSTQIKVK NSASVTVSPA
SAVQTSAGAT AYRFQSGSRR KAAQRSAPSR TTALEGTGAP GHPQASLGAA STENGGTHLP
PAKVLLSDKK PTPQRVIKLK RTPLCATTPS LATPTATRQA SSLKPLPSDA ARALGVRTEN
GKDKGN
//
