ID A0A0D9RRR0_CHLSB Unreviewed; 520 AA.
AC A0A0D9RRR0;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=MSL complex subunit 3 {ECO:0000313|Ensembl:ENSCSAP00000011299.1};
GN Name=MSL3 {ECO:0000313|Ensembl:ENSCSAP00000011299.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000011299.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000011299.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000011299.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AQIB01143534; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007989212.1; XM_007991021.1.
DR AlphaFoldDB; A0A0D9RRR0; -.
DR STRING; 60711.ENSCSAP00000011299; -.
DR Ensembl; ENSCSAT00000013293.1; ENSCSAP00000011299.1; ENSCSAG00000015196.1.
DR GeneID; 103231592; -.
DR CTD; 10943; -.
DR eggNOG; KOG3001; Eukaryota.
DR GeneTree; ENSGT00950000182965; -.
DR OMA; DTEYAHL; -.
DR OrthoDB; 2878816at2759; -.
DR BioGRID-ORCS; 103231592; 1 hit in 9 CRISPR screens.
DR Proteomes; UP000029965; Chromosome X.
DR Bgee; ENSCSAG00000015196; Expressed in blood and 7 other cell types or tissues.
DR GO; GO:0072487; C:MSL complex; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR GO; GO:0046972; F:histone H4K16 acetyltransferase activity; IEA:Ensembl.
DR GO; GO:0035064; F:methylated histone binding; IEA:Ensembl.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:Ensembl.
DR CDD; cd18983; CBD_MSL3_like; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 1.10.274.30; MRG domain; 2.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR000953; Chromo/chromo_shadow_dom.
DR InterPro; IPR008676; MRG.
DR InterPro; IPR038217; MRG_C_sf.
DR InterPro; IPR026541; MRG_dom.
DR InterPro; IPR025995; Tudor-knot.
DR PANTHER; PTHR10880; MORTALITY FACTOR 4-LIKE PROTEIN; 1.
DR PANTHER; PTHR10880:SF15; MRG DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF05712; MRG; 1.
DR Pfam; PF11717; Tudor-knot; 1.
DR SMART; SM00298; CHROMO; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 1.
DR PROSITE; PS51640; MRG; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 32..90
FT /note="Chromo"
FT /evidence="ECO:0000259|SMART:SM00298"
FT REGION 114..168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 297..408
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..137
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 138..153
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 154..168
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 297..331
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 333..356
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 357..381
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 520 AA; 59728 MW; 00859AFC414ADEC8 CRC64;
MSASEGMKFK FHSGEKVLCF EPDPTKARVL YDAKIVDVIV GKDEKGRKIP EYLIHFNGWN
RSWDRWAAED HVLRDTDENR RLQRKLARKA VARLRSTGRK KKRCRLPGVD SVLKGLPTEE
KDENDENSLS SSSDCSEDKD EEISEESDIE EKTEKEEPEL QTKREMEERT ITIEIPEVLK
KQLEDDCYYV NRRKRLVKLP CQTNIITILE SYVKHFAINA AFSANERPRH HHVMPHANMN
VHYIPAEKNV DLCKEMVDGL RITFDYTLPL VLLYPYEQAQ YKKVTSSKFF LPIKESATST
NRSQEELSPS PPLLNPSTPQ STESQPTTGE PATPKRRKAE PEALQSLRRS TRHSANSDRL
SESSASPQPK RRQQDTSTSM PKLFLHLEKK TPVHSRSSSP IPLTPSKEGS AVFAGFEGRR
TNEINEVLSW KLVPDNYPPG DQPPPPSYIY GAQHLLRLFV KLPEILGKMS FSEKNLKALL
KHFDLFLRFL AEYHDDFFPE SAYVTACEAH YSTKNPRAIY
//
