ID A0A0D9RT52_CHLSB Unreviewed; 1203 AA.
AC A0A0D9RT52;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Potassium sodium-activated channel subfamily T member 1 {ECO:0000313|Ensembl:ENSCSAP00000011791.1};
GN Name=KCNT1 {ECO:0000313|Ensembl:ENSCSAP00000011791.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000011791.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000011791.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000011791.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AQIB01148106; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01148107; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01148108; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01148109; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A0D9RT52; -.
DR STRING; 60711.ENSCSAP00000011791; -.
DR Ensembl; ENSCSAT00000013801.1; ENSCSAP00000011791.1; ENSCSAG00000015708.1.
DR eggNOG; KOG3193; Eukaryota.
DR GeneTree; ENSGT00940000156880; -.
DR OMA; MMNDLNR; -.
DR Proteomes; UP000029965; Chromosome 12.
DR Bgee; ENSCSAG00000015708; Expressed in caudate nucleus and 4 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:UniProt.
DR GO; GO:0071805; P:potassium ion transmembrane transport; IEA:UniProt.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR003929; K_chnl_BK_asu.
DR InterPro; IPR013099; K_chnl_dom.
DR InterPro; IPR047871; K_chnl_Slo-like.
DR PANTHER; PTHR10027; CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN; 1.
DR PANTHER; PTHR10027:SF14; POTASSIUM CHANNEL SUBFAMILY T MEMBER 1; 1.
DR Pfam; PF03493; BK_channel_a; 1.
DR Pfam; PF07885; Ion_trans_2; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 64..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 121..142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 218..239
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 245..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 226..293
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 451..545
FT /note="Calcium-activated potassium channel BK alpha
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF03493"
FT REGION 626..655
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1016..1050
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1177..1203
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1203 AA; 136635 MW; 84C1FE1F4BEEE7D7 CRC64;
MSDLDSEVLP LPPRYRFRDL LLGDPSFQND DRVQVEFYVN ENTFKERLKL FFIKNQRSSL
RIRLFNFSLK LLTCLLYIVR VLLDDPALGI GCWGCPKQNY SFNDSSSEIN WAPILWVERK
MTLWAIQVIV AIISFLETML LIYLSYKGNI WEQIFRVSFV LEMINTLPFI ITIFWPPLRN
LFIPVFLNCW LAKHALENMI NDFHRAILRT QSAMFNQVLI LFCTLLCLVF TGTCGIQHLE
RAGENLSLLT SFYFCIVTFS TVGYGDVTPK IWPSQLLVVI MICVALVVLP LQFEELVYLW
MERQKSGGNY SRHRAQTEKH VVLCVSSLKI DLLMDFLNEF YAHPRLQDYY VVILCPTEMD
VQVRRVLQIP LWSQRVIYLQ GSALKDQDLM RAKMDNGEAC FILSSRNEVD RTAADHQTIL
RAWAVKDFAP NCPLYVQILK PENKFHVKFA DHVVCEEECK YAMLALNCIC PATSTLITLL
VHTSRGQEGQ ESPEQWQRMY GRCSGNEVYH IRMGDSKFFR EYEGKSFTYA AFHAHKKYGV
CLIGLKREDN KSILLNPGPR HILAASDTCF YINITKEENS AFIFKQEEKR KKRAFSGQGL
HEGPARLPVH SIIASMGTVA MDLQGTEHRP TQSGGGGGGN KLALPTENGS GSRRPSIAPV
LELADSSALL PCDLLSDQSE DEVTPSDDEG LSVVEYVKGY PPNSPYIGSS PTLCHLLPVK
APFCCLRLDK GCKHNSYEDA KAYGFKNKLI IVSAETAGNG LYNFIVPLRA YYRSRKELNP
IVLLLDNKPD HHFLEAICCF PMVYYMEGSV DNLDSLLQCG IIYADNLVVV DKESTMSAEE
DYMADAKTIV NVQTMFRLFP SLSITTELTH PSNMRFMQFR AKDSYSLALS KLEKRERENG
SNLAFMFRLP FAAGRVFSIS MLDTLLYQSF VKDYMITITR LLLGLDTTPG SGYLCAMKIT
EGDLWIRTYG RLFQKLCSSS AEIPIGIYRT ESHVFSTSEP HDLRAQSQIS VNMEDCEDTR
EARGPWGSRA GTGGSSHGRH TGGSDPAEHR LLRRKSLQWA RRLSRKGPKQ AGRAAAAEWI
SQQRLSLYRR SERQELSELV KNRMKHLGLP TTGYEDVANL TASDVMNRVN LGYLQDEMND
HQNTLSYVLI NPPPDTRLEP SDIVYLIRSD PLAHVASSSQ SRKSSCSHKL SSCNPETRDE
TQL
//
