ID A0A0D9RWE5_CHLSB Unreviewed; 578 AA.
AC A0A0D9RWE5;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Acyl-coenzyme A oxidase {ECO:0000256|PIRNR:PIRNR000168};
GN Name=ACOXL {ECO:0000313|Ensembl:ENSCSAP00000012934.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000012934.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000012934.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000012934.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the acyl-CoA oxidase family.
CC {ECO:0000256|ARBA:ARBA00006288, ECO:0000256|PIRNR:PIRNR000168}.
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DR EMBL; AQIB01144172; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01144173; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A0D9RWE5; -.
DR STRING; 60711.ENSCSAP00000012934; -.
DR Ensembl; ENSCSAT00000014978.1; ENSCSAP00000012934.1; ENSCSAG00000016889.1.
DR eggNOG; KOG0135; Eukaryota.
DR GeneTree; ENSGT00940000161693; -.
DR OMA; SINKRFA; -.
DR Proteomes; UP000029965; Chromosome 14.
DR Bgee; ENSCSAG00000016889; Expressed in blood.
DR GO; GO:0005777; C:peroxisome; IEA:InterPro.
DR GO; GO:0003997; F:acyl-CoA oxidase activity; IEA:InterPro.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0006635; P:fatty acid beta-oxidation; IEA:InterPro.
DR Gene3D; 2.40.110.10; Butyryl-CoA Dehydrogenase, subunit A, domain 2; 1.
DR Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 2.
DR InterPro; IPR006091; Acyl-CoA_Oxase/DH_mid-dom.
DR InterPro; IPR046373; Acyl-CoA_Oxase/DH_mid-dom_sf.
DR InterPro; IPR012258; Acyl-CoA_oxidase.
DR InterPro; IPR002655; Acyl-CoA_oxidase_C.
DR InterPro; IPR036250; AcylCo_DH-like_C.
DR InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR PANTHER; PTHR10909:SF378; ACYL-COENZYME A OXIDASE-LIKE PROTEIN; 1.
DR PANTHER; PTHR10909; ELECTRON TRANSPORT OXIDOREDUCTASE; 1.
DR Pfam; PF01756; ACOX; 1.
DR Pfam; PF02770; Acyl-CoA_dh_M; 1.
DR PIRSF; PIRSF000168; Acyl-CoA_oxidase; 2.
DR SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 2.
DR SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRNR:PIRNR000168};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|PIRNR:PIRNR000168};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965}.
FT DOMAIN 90..197
FT /note="Acyl-CoA oxidase/dehydrogenase middle"
FT /evidence="ECO:0000259|Pfam:PF02770"
FT DOMAIN 417..543
FT /note="Acyl-CoA oxidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01756"
FT BINDING 93
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000168-2"
FT BINDING 132
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000168-2"
SQ SEQUENCE 578 AA; 65183 MW; 8980B9456AC1C11D CRC64;
MRALTVQRVR FAMGLPLLKR AVQDLQRKTK NFVSRSLVLG EVLSMADMAT GVKCGIVYWL
FGGAIRNVGS PEHVTKWFQP LQEQKYTGMF AMTERGHGSN VRGIQTEATF DLSAQEFVID
TPCENAEKMY IGNAMYGNYA AVFAQLIIDG RSQGSHCFIV PVRDENGSFY PGMTAIDRKY
KEGLHGVDNG ILIFDKVQIP ENLLDKFGSV APDGQYHSPT RNKSARFSAM LAALTPLRLA
VAFQAMGAMK LGLTIAVRYS HSWRQFGPKT KEEVKIFEHQ TQLWLMPPLA TALALTFVSR
YAGALLDEDV FQGKELVNSH SLQALVAGLK AYSTWENIRC LQDCCECTGG MVVGQELLAQ
YTKQYEEKPL FGLLQNWAES VGDKLRTSFL AFNMDTVDDL AFLLKAVKFR ERILQWGLVT
RIYYKVKTKK EDFFHTWNSC LHHMASLSLA HTHRVTLEQF SLAVKSCPDQ EDQTLLMKFC
LLYGTKLVFQ ERAWYLEHKY LTPVASTRIR NQLLDVCDSV KDDALRVIPA FNIPHTNLHA
PIAGISNPRF AWAFYPAPLQ PLPREGARSQ RPKLGAKL
//
