ID A0A0E0JR04_ORYPU Unreviewed; 287 AA.
AC A0A0E0JR04;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=NADP-dependent oxidoreductase domain-containing protein {ECO:0000259|Pfam:PF00248};
OS Oryza punctata (Red rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=4537 {ECO:0000313|EnsemblPlants:OPUNC01G36050.1};
RN [1] {ECO:0000313|EnsemblPlants:OPUNC01G36050.1}
RP NUCLEOTIDE SEQUENCE.
RA Wing R.;
RT "Oryza genome evolution.";
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:OPUNC01G36050.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
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DR AlphaFoldDB; A0A0E0JR04; -.
DR STRING; 4537.A0A0E0JR04; -.
DR EnsemblPlants; OPUNC01G36050.1; OPUNC01G36050.1; OPUNC01G36050.
DR EnsemblPlants; OPUNC01G36050.2; OPUNC01G36050.2; OPUNC01G36050.
DR Gramene; OPUNC01G36050.1; OPUNC01G36050.1; OPUNC01G36050.
DR Gramene; OPUNC01G36050.2; OPUNC01G36050.2; OPUNC01G36050.
DR eggNOG; KOG1577; Eukaryota.
DR HOGENOM; CLU_023205_0_0_1; -.
DR OMA; EIYLRWC; -.
DR Proteomes; UP000026962; Chromosome 1.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd19125; AKR_AKR4C1-15; 1.
DR Gene3D; 3.20.20.100; NADP-dependent oxidoreductase domain; 1.
DR InterPro; IPR020471; AKR.
DR InterPro; IPR044498; AKR4C.
DR InterPro; IPR018170; Aldo/ket_reductase_CS.
DR InterPro; IPR023210; NADP_OxRdtase_dom.
DR InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR PANTHER; PTHR11732; ALDO/KETO REDUCTASE; 1.
DR PANTHER; PTHR11732:SF386; OS01G0847700 PROTEIN; 1.
DR Pfam; PF00248; Aldo_ket_red; 1.
DR PIRSF; PIRSF000097; AKR; 2.
DR PRINTS; PR00069; ALDKETRDTASE.
DR SUPFAM; SSF51430; NAD(P)-linked oxidoreductase; 1.
DR PROSITE; PS00798; ALDOKETO_REDUCTASE_1; 1.
DR PROSITE; PS00062; ALDOKETO_REDUCTASE_2; 1.
DR PROSITE; PS00063; ALDOKETO_REDUCTASE_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000026962}.
FT DOMAIN 17..178
FT /note="NADP-dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF00248"
FT ACT_SITE 49
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000097-1"
FT BINDING 111
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000097-2"
FT SITE 78
FT /note="Lowers pKa of active site Tyr"
FT /evidence="ECO:0000256|PIRSR:PIRSR000097-3"
SQ SEQUENCE 287 AA; 31890 MW; A4C6462CADD1602A CRC64;
MAKHFVLNTG AKIPSVGLGT WQSDPGVVGN AVYAAVKAGY RHIDCARAYN NEKEVGLALK
KLFEEGVVQR EDLFITSKLW CDHHAPEDVP EALDETLNDL QLEYLDLYLI HWPFRTKKGS
SIGNPESYLP PDIPSTWAAM EKLYDSGKTR AIGVSNFSSK KLGDLLAVAR VPPAVDQAYS
PLGSPGSTFM NGNVLKEPII ISIAEKLGKT AAQVALCWNI QMGHTVLPKS VSEERIKQNI
DVYDWSIPED LLVKFSEIKQ VRLLRGNFIV NPQSVYKTHE ELWDGEI
//
