ID   A0A0E0M499_ORYPU        Unreviewed;      1107 AA.
AC   A0A0E0M499;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   RecName: Full=MutL C-terminal dimerisation domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Oryza punctata (Red rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX   NCBI_TaxID=4537 {ECO:0000313|EnsemblPlants:OPUNC09G17330.1};
RN   [1] {ECO:0000313|EnsemblPlants:OPUNC09G17330.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Wing R.;
RT   "Oryza genome evolution.";
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblPlants:OPUNC09G17330.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (APR-2015) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the DNA mismatch repair MutL/HexB family.
CC       {ECO:0000256|ARBA:ARBA00006082}.
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DR   AlphaFoldDB; A0A0E0M499; -.
DR   EnsemblPlants; OPUNC09G17330.1; OPUNC09G17330.1; OPUNC09G17330.
DR   Gramene; OPUNC09G17330.1; OPUNC09G17330.1; OPUNC09G17330.
DR   Proteomes; UP000026962; Chromosome 9.
DR   GO; GO:0032300; C:mismatch repair complex; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR   GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR   Gene3D; 3.30.230.10; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 3.30.1540.20; MutL, C-terminal domain, dimerisation subdomain; 1.
DR   Gene3D; 3.30.1370.100; MutL, C-terminal domain, regulatory subdomain; 1.
DR   InterPro; IPR013507; DNA_mismatch_S5_2-like.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR038973; MutL/Mlh/Pms-like.
DR   InterPro; IPR014790; MutL_C.
DR   InterPro; IPR042120; MutL_C_dimsub.
DR   InterPro; IPR042121; MutL_C_regsub.
DR   InterPro; IPR037198; MutL_C_sf.
DR   InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR   InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR   PANTHER; PTHR10073; DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL; 1.
DR   PANTHER; PTHR10073:SF47; DNA MISMATCH REPAIR PROTEIN MLH3; 1.
DR   Pfam; PF13589; HATPase_c_3; 1.
DR   SMART; SM01340; DNA_mis_repair; 1.
DR   SMART; SM00853; MutL_C; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF118116; DNA mismatch repair protein MutL; 1.
DR   SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
PE   3: Inferred from homology;
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   Reference proteome {ECO:0000313|Proteomes:UP000026962}.
FT   DOMAIN          215..314
FT                   /note="DNA mismatch repair protein S5"
FT                   /evidence="ECO:0000259|SMART:SM01340"
FT   DOMAIN          873..1025
FT                   /note="MutL C-terminal dimerisation"
FT                   /evidence="ECO:0000259|SMART:SM00853"
SQ   SEQUENCE   1107 AA;  125299 MW;  3393F4DA40FC878B CRC64;
     MQTIKRLPKS VHSSLRSSIV LFDLSRVVEE LVYNSIDANA SKIDISVNVR ACYVKVEDDG
     CGITRDELVR VGEKYATSKF HNVMVDEEAS SRSFGLNGEA LASLSDISVV EVRTKARGRP
     NSYCKIIKGS KCSHLGIDEQ REVVGTTVIV RELFYNQPVR RKQMQSSHKR ELHLVKKSVL
     RVALIHPQVS LRLFDTESDD ELLYTIPSSS PLPLVSNILG KNVSSCLHEI VTSDKHFALS
     GHISRPTDVF CNKEIDVRSK KRQKNEVYPA YLLNLCCPRS SYDLHFEPSQ TIVEFKDWQT
     VMYFFERTIT DYWKKHAPQL PEVKAIGNDT CVPLERDVKS SQELLRHHGV QKKEDVTELY
     QTALQKNTVK DMNFDTAAPA GLKGNYLSLD MEPSTWRVCY DQISDASHTD DVARNGQKFG
     HKQICSLQSY SYEWLEDGSS LLEDSDLSSA NPTICKMQKT EDIFHGHAYS GKFGLLQDAE
     IEIGPEIKLQ ESCFESPNKP NRMTCDFVQK QTNIEAHISG RDGFYVDFDK LNEDCLLNEI
     SKTITDVSCP QMPHFNDGFY PEDVGSSKSS CSVMKKSSKR KNNANAISQM NFHDMQAVCK
     SDYMDRSFIK DTCGLHFFHP FSLADTPRSH SRARIDLDLH GRSNESINSW NCENIGSDYR
     FTSDRFNIDS SMIFEGSKHL NNFGNGTQSP SYFNHEYCSV DQFASEQDQI HLKSKHDARM
     SYDISPEKSS TGCHLNVSFS QVAKGSKLTE DQYGCSQRPR LSRDITPVQE YTSHMNTTQP
     IPETCSNEFS DLNFSFKGNV KMCEEKCSDE LEDSTASDEI TKWRDDSDHH AVEHFVLSVI
     SLCTIFYAHD FISLCSVLVP ECIDKNCFEE ARVLLQLDKK FIPVISGEHA ADERIRLEEL
     RRKVLSDDGR GITYLSSEED LVLPETGFQL FQKYMQQIQS WGWIINSSNS CESFKKNMNV
     LRRQSRLLTL AAVPCILGVT LTGKDLMDFI QQLDDTDGSS AFPPAVIRIL NFKACRGAIM
     FGDPLLPSEC SLIIEELKAT SLCFQCAHGR PTTVPIVNVA SLRDELARLG AVNGRQEETW
     HGLSHHGPSL ERARTRLREL RKLRGGL
//