ID   A0A0E0MXF3_ORYRU        Unreviewed;      1218 AA.
AC   A0A0E0MXF3;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   RecName: Full=RNA-dependent RNA polymerase {ECO:0000256|RuleBase:RU363098};
DE            EC=2.7.7.48 {ECO:0000256|RuleBase:RU363098};
OS   Oryza rufipogon (Brownbeard rice) (Asian wild rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX   NCBI_TaxID=4529 {ECO:0000313|EnsemblPlants:ORUFI01G20360.1, ECO:0000313|Proteomes:UP000008022};
RN   [1] {ECO:0000313|Proteomes:UP000008022}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=cv. W1943 {ECO:0000313|Proteomes:UP000008022};
RA   Zhao Q.;
RL   Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblPlants:ORUFI01G20360.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- FUNCTION: Probably involved in the RNA silencing pathway and required
CC       for the generation of small interfering RNAs (siRNAs).
CC       {ECO:0000256|RuleBase:RU363098}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.48; Evidence={ECO:0000256|ARBA:ARBA00024517,
CC         ECO:0000256|RuleBase:RU363098};
CC   -!- SIMILARITY: Belongs to the RdRP family. {ECO:0000256|ARBA:ARBA00005762,
CC       ECO:0000256|RuleBase:RU363098}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A0E0MXF3; -.
DR   SMR; A0A0E0MXF3; -.
DR   STRING; 4529.A0A0E0MXF3; -.
DR   EnsemblPlants; ORUFI01G20360.1; ORUFI01G20360.1; ORUFI01G20360.
DR   Gramene; ORUFI01G20360.1; ORUFI01G20360.1; ORUFI01G20360.
DR   eggNOG; KOG0988; Eukaryota.
DR   HOGENOM; CLU_001366_3_1_1; -.
DR   OMA; HPKWVKK; -.
DR   Proteomes; UP000008022; Unassembled WGS sequence.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0010492; P:maintenance of shoot apical meristem identity; IEA:EnsemblPlants.
DR   GO; GO:0035194; P:regulatory ncRNA-mediated post-transcriptional gene silencing; IEA:EnsemblPlants.
DR   InterPro; IPR007855; RNA-dep_RNA_pol_euk-typ.
DR   PANTHER; PTHR23079; RNA-DEPENDENT RNA POLYMERASE; 1.
DR   PANTHER; PTHR23079:SF18; RNA-DEPENDENT RNA POLYMERASE 6; 1.
DR   Pfam; PF05183; RdRP; 1.
PE   3: Inferred from homology;
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU363098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008022};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU363098};
KW   RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW   ECO:0000256|RuleBase:RU363098};
KW   RNA-mediated gene silencing {ECO:0000256|RuleBase:RU363098};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363098}.
SQ   SEQUENCE   1218 AA;  136534 MW;  984FD38DC5474482 CRC64;
     MRSPRGGAAA QPSGRRGDTT AAAAGDLVTT QVSLGGFDAG VAAGDLADFL EHEVGLVWRC
     RVKTSWTPPD SYPDFALPTA PASASAAAAP PRYDRVPPHA FVHFARPEGA RRAADLAGET
     RLILRGKPLR VASAPDSSLR VSRRSSIAPF RFPDVRLEVG ALPSPGAFLA AWRGPDAGLD
     LSVDPFDGCC RLVFTRDTAF TFPGFREVAA IRCDVKLEFP VRDVLEVRLY RLDCSLLLRL
     AAAPLVHYRT ADDDFHEPVP FDLLDDDDPW IRTTDITPSG AIGRCGVYRI SFSARFWPKM
     DRALDYMRER RVAIVDCGGG WGPRRGLTVR DELEFGEPMQ DVFFCLQHAE GLKFPLLFMV
     NALVHKGIIN QHQLTPEFFS LLGRSEENVN VAALRDFWGD KFPVFDACGR LKKALNRVAR
     NPKLLCSKVG DDHAEVRRLV ITPTRAYCLP PEVERSNRVL RHYHEVADRF LRVTFMDEGM
     QVLNNNVLNS FTAPIVKDLM SNFFQQKTTV YKRVRMLLTE GFHMCGRKYS FLAFSSNQLR
     DKSAWFFAED RKTTVEAIRK WMGRFTSKNV AKHAARMGQC FSSTYATVTM RPDEVDESFD
     DVVHNEYIFS DGIGKITPDL ALEVAERLQL TDNPPSAYQI RFAGFKGVIA VWQGHGDGTR
     LFLRPSMRKF ESNHLVLEVV SWTKFQPGFL NRQIIILLSS LNVPDSIFWQ MQETMLSNLN
     NILSDRDVAF EVLTTSCADD GNTAALMLSA GFEPRTEPHL KAMLLAIRSA QLQDLLEKAR
     IFVPKGRWLM GCLDELGVLE QGQCFIRATV PSLNSYFVKH GSRFSSTDKN TEVILGTVVI
     AKNPCLHPGD VRILEAVDVP ELHHLVDCLV FPQKGERPHA NEASGSDLDG DLYFVTWDEK
     LIPPGKKSWN PMDYSPPEAK QLPRQVSQHD IIDFFLKNMI SENLGRICNA HVVHADLSEY
     GAMDEKCIHL AELAATAVDF PKTGKLAIMP PHLKPKVYPD FMGKEDGQSY KSEKILGRLY
     RSIQEASNGD VVSQEVCTPN DLPYDIDLEV PGASDFLASA WQCKCSYDAQ LSALLSQYRV
     RTEAELVTGH ITFLVKNSSK KQGDIKDRLK TAYSALRKEF KSTFESIASD QCEIGDDEKN
     LLYEMKASAW YQVTYHPKWV EKSRGILGPD GEEIPASLSF AWIPVDYLAR IKLRCHGKVR
     VEGQKPVERL AAYISERI
//