ID   A0A0E0PDP1_ORYRU        Unreviewed;       940 AA.
AC   A0A0E0PDP1;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   RecName: Full=HP domain-containing protein {ECO:0000259|PROSITE:PS51089};
OS   Oryza rufipogon (Brownbeard rice) (Asian wild rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX   NCBI_TaxID=4529 {ECO:0000313|EnsemblPlants:ORUFI04G25980.1, ECO:0000313|Proteomes:UP000008022};
RN   [1] {ECO:0000313|Proteomes:UP000008022}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=cv. W1943 {ECO:0000313|Proteomes:UP000008022};
RA   Zhao Q.;
RL   Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblPlants:ORUFI04G25980.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC       {ECO:0000256|ARBA:ARBA00004245}.
CC   -!- SIMILARITY: Belongs to the villin/gelsolin family.
CC       {ECO:0000256|ARBA:ARBA00008418}.
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DR   AlphaFoldDB; A0A0E0PDP1; -.
DR   STRING; 4529.A0A0E0PDP1; -.
DR   EnsemblPlants; ORUFI04G25980.1; ORUFI04G25980.1; ORUFI04G25980.
DR   Gramene; ORUFI04G25980.1; ORUFI04G25980.1; ORUFI04G25980.
DR   eggNOG; KOG0443; Eukaryota.
DR   HOGENOM; CLU_002568_2_1_1; -.
DR   OMA; CWEGVHS; -.
DR   Proteomes; UP000008022; Unassembled WGS sequence.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR   GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR   GO; GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.
DR   GO; GO:0007015; P:actin filament organization; IEA:UniProt.
DR   CDD; cd11290; gelsolin_S1_like; 1.
DR   CDD; cd11289; gelsolin_S2_like; 1.
DR   CDD; cd11293; gelsolin_S4_like; 1.
DR   CDD; cd11288; gelsolin_S5_like; 1.
DR   Gene3D; 3.40.20.10; Severin; 6.
DR   Gene3D; 1.10.950.10; Villin headpiece domain; 1.
DR   InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
DR   InterPro; IPR007123; Gelsolin-like_dom.
DR   InterPro; IPR036180; Gelsolin-like_dom_sf.
DR   InterPro; IPR007122; Villin/Gelsolin.
DR   InterPro; IPR003128; Villin_headpiece.
DR   InterPro; IPR036886; Villin_headpiece_dom_sf.
DR   PANTHER; PTHR11977; VILLIN; 1.
DR   PANTHER; PTHR11977:SF49; VILLIN-4; 1.
DR   Pfam; PF00626; Gelsolin; 4.
DR   Pfam; PF02209; VHP; 1.
DR   PRINTS; PR00597; GELSOLIN.
DR   SMART; SM00262; GEL; 6.
DR   SMART; SM00153; VHP; 1.
DR   SUPFAM; SSF55753; Actin depolymerizing proteins; 4.
DR   SUPFAM; SSF82754; C-terminal, gelsolin-like domain of Sec23/24; 2.
DR   SUPFAM; SSF47050; VHP, Villin headpiece domain; 1.
DR   PROSITE; PS51089; HP; 1.
PE   3: Inferred from homology;
KW   Actin capping {ECO:0000256|ARBA:ARBA00022467};
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008022};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          875..940
FT                   /note="HP"
FT                   /evidence="ECO:0000259|PROSITE:PS51089"
FT   REGION          737..783
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          795..826
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          838..898
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        767..781
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   940 AA;  104782 MW;  7DAF24D82CE94761 CRC64;
     MALYFSPLVL SPDSGSSLLS PQGFSNFHCH QEHTGFSGLE VWRIENFKPV PVPTSSHGKF
     YMGDSYIILK TTALKNGSFR HDLHYWLGKD TSQDEAGTAA ILTVELDAAL GGRAVQYREV
     QGGETEKLLS YFRPCIMPQP GGVASGFNHV EVNQQDHVTR LYVCQGKHVV HVKEVPFVRS
     SLNHEDIFIL DTANKIFQFN GSNSCIQERA KALEVVQYIK DTFHEGKCEV AAVEDGKLMA
     DTEAGEFWGL FGGFAPLPKK TSSEDNGDDK ETVTKLLCFN QGTLEHISFE SLEHELLETN
     KCYLLDCGAE MYVWMGRGTS LQVRKGASEA AEKLLIDENR KGSNVIKVIE GFETIMFKSK
     FNKWPPTPDL KLSSEDGRGK VAALLRSQGL DVKGLMKAAP EEEEPQPYID CTGHLQVWRV
     NGDGKTLLSS SDQSKLYTGD CYIFQYTYTG DDKEECLIGT WFGKKSVEED RTSAISLASK
     MFQAAKFQAA QARLYEGKEP IQFFVIFQSL QVFKGGLSSG YKNFIAVNGT DDDTYVEGGL
     ALFRIQGSGS ENMQAIQVDA VSSSLNSSYC YILHNGNTVF TWTGNLTTSL DNDLVERQLD
     VIKPDLPSRS QKEGRETDQF WELLGGKCKY SNKKIGKENE SDPHLFSCIL SKENLKVKEI
     HHFTQDDLMA EDIFVLDCRT DLFVWVGQEV DAKLRSQAMD IEGSEPQFFT RFFTWDSAKS
     LMHGSSYQRK LAIVKGGATP SLDKPKRRTP AFSGRNAGQD KSQQRTRSMS HSPERHRIRG
     RSPAFTAIAS AFENPSTRYL STPPPAVKKL FPRSGGSELP KTSSKQSAIN ALTSAFEGPT
     KSTIPKSVKA SPEAEKAIQE EGSTIGESEN EPEDDENSTI YPYERLTTTS DDPAPDIDVT
     KREVYLSSVE FAEKFGMTRA SFKNLPKWKQ NRLKSDLQLF
//