ID A0A0E0PT32_ORYRU Unreviewed; 743 AA.
AC A0A0E0PT32;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=transketolase {ECO:0000256|ARBA:ARBA00013152};
DE EC=2.2.1.1 {ECO:0000256|ARBA:ARBA00013152};
OS Oryza rufipogon (Brownbeard rice) (Asian wild rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=4529 {ECO:0000313|EnsemblPlants:ORUFI06G02110.1, ECO:0000313|Proteomes:UP000008022};
RN [1] {ECO:0000313|Proteomes:UP000008022}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. W1943 {ECO:0000313|Proteomes:UP000008022};
RA Zhao Q.;
RL Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:ORUFI06G02110.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate =
CC aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate;
CC Xref=Rhea:RHEA:10508, ChEBI:CHEBI:57483, ChEBI:CHEBI:57737,
CC ChEBI:CHEBI:58273, ChEBI:CHEBI:59776; EC=2.2.1.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001027};
CC -!- COFACTOR:
CC Name=Co(2+); Xref=ChEBI:CHEBI:48828;
CC Evidence={ECO:0000256|ARBA:ARBA00001941};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the transketolase family.
CC {ECO:0000256|ARBA:ARBA00007131}.
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DR AlphaFoldDB; A0A0E0PT32; -.
DR SMR; A0A0E0PT32; -.
DR STRING; 4529.A0A0E0PT32; -.
DR EnsemblPlants; ORUFI06G02110.1; ORUFI06G02110.1; ORUFI06G02110.
DR Gramene; ORUFI06G02110.1; ORUFI06G02110.1; ORUFI06G02110.
DR eggNOG; KOG0523; Eukaryota.
DR HOGENOM; CLU_009227_0_0_1; -.
DR OMA; ADYMRGS; -.
DR Proteomes; UP000008022; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004802; F:transketolase activity; IEA:UniProtKB-EC.
DR CDD; cd07033; TPP_PYR_DXS_TK_like; 1.
DR CDD; cd02012; TPP_TK; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR005478; Transketolase_bac-like.
DR InterPro; IPR033248; Transketolase_C.
DR InterPro; IPR049557; Transketolase_CS.
DR InterPro; IPR033247; Transketolase_fam.
DR InterPro; IPR005474; Transketolase_N.
DR NCBIfam; TIGR00232; tktlase_bact; 1.
DR PANTHER; PTHR43522; TRANSKETOLASE; 1.
DR PANTHER; PTHR43522:SF2; TRANSKETOLASE 1-RELATED; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR Pfam; PF00456; Transketolase_N; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
DR PROSITE; PS00801; TRANSKETOLASE_1; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000008022};
KW Thiamine pyrophosphate {ECO:0000256|ARBA:ARBA00023052};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 434..606
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
FT REGION 41..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 743 AA; 80029 MW; 8F6D6F68B8D33A26 CRC64;
MAAHSVAAAH ATIAARAGAA APAPAPPERL GFRLSALAGR GLRSPLPPRR GAPSASASRR
RHNNRVRAAA VETLEGQAAT GALLEKSVNT IRFLAIDAVE KANSGHPGLP MGCAPMGHIL
YDEVMRYNPK NPYWFNRDRF ILSAGHGCML QYALLHLAGY DAVLEEDLKQ FRQWGSKTPG
HPENFETPGV EVTTGPLGQG IANAVGLALA EKHLAARFNK PDSEIVDHYT YCILGDGCQM
EGISNEACSL AGHWGLGKLI AFYDDNHISI DGDTEIAFTE DVSARFEALG WHTIWVKNGN
DGYDEIRAAI KEAKAVTDKP TLIKVTTTIG FGSPNKANSY SVHGSALGTK EVEATRENLG
WPYEPFFVPE DVKSHWSRHV PQGAAFEADW NAKFAEYEKK YPEDAATLKS IVSGELPAGW
ADALPKYTPE SPADATRNLS QQCLNALAKV VPGLLGGSAD LASSNMTLLK MFGDFQKDTP
EERNVRFGVR EHGMGAICNG IALHSPGLIP YCATFFVFTD YMRAAMRISA LCEAGVIYVM
THDSIGLGED GPTHQPIEHL VSFRAMPNIL MLRPADGNET AGAYKIAVLN RKRPSVLALS
RQKLAQLPGT SIEGVEKGGY IVSDNSTGNK PDFIVMSTGS ELEIVAKAAD ELRKEGKTVR
VVSFVCWELF DEQSAEYKES VLPEAVTARV SLEAGSTLGW QKYVGSKGKA IGIDKFGASA
PAGKIYQEYG ITAENVIATA KSL
//
