ID A0A0E0QTT9_ORYRU Unreviewed; 716 AA.
AC A0A0E0QTT9;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Translation initiation factor IF-2, mitochondrial {ECO:0000256|ARBA:ARBA00044200};
OS Oryza rufipogon (Brownbeard rice) (Asian wild rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=4529 {ECO:0000313|EnsemblPlants:ORUFI09G17680.1, ECO:0000313|Proteomes:UP000008022};
RN [1] {ECO:0000313|Proteomes:UP000008022}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. W1943 {ECO:0000313|Proteomes:UP000008022};
RA Zhao Q.;
RL Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:ORUFI09G17680.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- FUNCTION: One of the essential components for the initiation of protein
CC synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis
CC and promotes its binding to the 30S ribosomal subunits. Also involved
CC in the hydrolysis of GTP during the formation of the 70S ribosomal
CC complex. {ECO:0000256|ARBA:ARBA00025162}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. IF-2 subfamily.
CC {ECO:0000256|ARBA:ARBA00007733}.
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DR AlphaFoldDB; A0A0E0QTT9; -.
DR SMR; A0A0E0QTT9; -.
DR EnsemblPlants; ORUFI09G17680.1; ORUFI09G17680.1; ORUFI09G17680.
DR EnsemblPlants; ORUFI09G17680.2; ORUFI09G17680.2; ORUFI09G17680.
DR EnsemblPlants; ORUFI09G17680.3; ORUFI09G17680.3; ORUFI09G17680.
DR Gramene; ORUFI09G17680.1; ORUFI09G17680.1; ORUFI09G17680.
DR Gramene; ORUFI09G17680.2; ORUFI09G17680.2; ORUFI09G17680.
DR Gramene; ORUFI09G17680.3; ORUFI09G17680.3; ORUFI09G17680.
DR HOGENOM; CLU_006301_5_1_1; -.
DR Proteomes; UP000008022; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR CDD; cd01887; IF2_eIF5B; 1.
DR CDD; cd03702; IF2_mtIF2_II; 1.
DR CDD; cd03692; mtIF2_IVc; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR Gene3D; 3.40.50.10050; Translation initiation factor IF- 2, domain 3; 1.
DR HAMAP; MF_00100_B; IF_2_B; 1.
DR InterPro; IPR044145; IF2_II.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR000178; TF_IF2_bacterial-like.
DR InterPro; IPR015760; TIF_IF2.
DR InterPro; IPR023115; TIF_IF2_dom3.
DR InterPro; IPR036925; TIF_IF2_dom3_sf.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR NCBIfam; TIGR00487; IF-2; 1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43381:SF20; TRANSLATION INITIATION FACTOR IF-2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43381; TRANSLATION INITIATION FACTOR IF-2-RELATED; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF11987; IF-2; 1.
DR SUPFAM; SSF52156; Initiation factor IF2/eIF5b, domain 3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 2.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000008022}.
FT DOMAIN 195..365
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 716 AA; 77259 MW; 2947E989B6A1FF63 CRC64;
MAWRMLRRKD FHTGLVNLAS RVDHGGAKNF SSGTFGKLAD FVLSDTHTPI VKGAANCTAY
KHCTIRNFHA GVYMLAWSRK REEVAGLKAP KKEKRVKRET RTQPPVEAPY VAPKQKIAIK
SSPDKTVDIF DGMTLLDLSK RTGASIGALQ DILTDLGEKV ESEFDAISID LAELVAMELG
VNIRRMHTGE GTLEPRPAVV TIMGHVDHGK TSLLDSLRQT SVAAKEAGGI TQHIGAFVVE
MPSGASITFL DTPGHAAFSA MRARGAAVTD IVVLVVAADD GVMPQTLEAM SHAKAANVPI
VVAVNKCDKS GADPERVRIQ LGSEGLLLED MGGDVQVVEI SAVTKLGLDK LEEALLLQAE
IMDLKARIDG PAQAFVVEAR VDRGRGPLAT AIVKAGTLVS GQHIVVGAEW GRIRSLRDTA
GKITESAKPA MPVEIEGLRG LPMAGDDVVV VDSEERARML SQGRKKKQEK DRLRKIDEDM
TEEAEIGEET PERVEMPIIV KADVQGSVQA VTDALRSLNS PQVFVNIVHV GVGPISQHDI
DLAQACRAYI VGFNIRTPPS AITLAATQAN IKILLHKVIY HLLEEMGREI VEKAPGTPET
QVSGEAEVLN IFELKGRSKS KGPDIKIAGC RITDGHLSKT GTMRLLRSGD VVFEGPCASL
KREKQDAETV DKGNDCGLVI QDCNDFQVGD IVQCLEQVIR KPKFISTQSG AVRIEC
//
