ID A0A0E3NX61_9EURY Unreviewed; 1267 AA.
AC A0A0E3NX61;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=N-methylhydantoinase A/acetone carboxylase, beta subunit {ECO:0000313|EMBL:AKB25135.1};
DE EC=3.5.2.14 {ECO:0000313|EMBL:AKB25135.1};
DE EC=3.5.2.9 {ECO:0000313|EMBL:AKB25135.1};
GN ORFNames=MSMTP_1666 {ECO:0000313|EMBL:AKB25135.1};
OS Methanosarcina sp. MTP4.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=1434100 {ECO:0000313|EMBL:AKB25135.1, ECO:0000313|Proteomes:UP000033049};
RN [1] {ECO:0000313|EMBL:AKB25135.1, ECO:0000313|Proteomes:UP000033049}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MTP4 {ECO:0000313|EMBL:AKB25135.1,
RC ECO:0000313|Proteomes:UP000033049};
RA Henriksen J.R., Luke J., Reinhart S., Benedict M.N., Youngblut N.D.,
RA Metcalf M.E., Whitaker R.J., Metcalf W.W.;
RT "Methanogenic archaea and the global carbon cycle.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the oxoprolinase family.
CC {ECO:0000256|ARBA:ARBA00010403}.
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DR EMBL; CP009505; AKB25135.1; -; Genomic_DNA.
DR RefSeq; WP_048178732.1; NZ_CP009505.1.
DR AlphaFoldDB; A0A0E3NX61; -.
DR STRING; 1434100.MSMTP_1666; -.
DR GeneID; 24857005; -.
DR KEGG; metm:MSMTP_1666; -.
DR PATRIC; fig|1434100.4.peg.2219; -.
DR HOGENOM; CLU_002157_0_0_2; -.
DR OrthoDB; 8261at2157; -.
DR Proteomes; UP000033049; Chromosome.
DR GO; GO:0017168; F:5-oxoprolinase (ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR GO; GO:0047423; F:N-methylhydantoinase (ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR InterPro; IPR049517; ACX-like_C.
DR InterPro; IPR008040; Hydant_A_N.
DR InterPro; IPR002821; Hydantoinase_A.
DR InterPro; IPR003692; Hydantoinase_B.
DR InterPro; IPR045079; Oxoprolinase_fam.
DR PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR PANTHER; PTHR11365:SF23; HYPOTHETICAL 5-OXOPROLINASE (EUROFUNG)-RELATED; 1.
DR Pfam; PF19278; Hydant_A_C; 1.
DR Pfam; PF05378; Hydant_A_N; 1.
DR Pfam; PF01968; Hydantoinase_A; 1.
DR Pfam; PF02538; Hydantoinase_B; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:AKB25135.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000033049}.
FT DOMAIN 12..191
FT /note="Hydantoinase/oxoprolinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF05378"
FT DOMAIN 210..526
FT /note="Hydantoinase A/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF01968"
FT DOMAIN 542..708
FT /note="Acetophenone carboxylase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19278"
FT DOMAIN 726..1250
FT /note="Hydantoinase B/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF02538"
SQ SEQUENCE 1267 AA; 137206 MW; AC5D3A213438AFB6 CRC64;
MSSQSQKPLW QFWIDRGGTF TDIVARSPEG KLITHKLLSE DPGHYSDAAM HGIRQILGLP
KNAALPTKQI ESVKMGTTVG TNALLERKGE RTVLLITRGF GDALRIGYQN RPDIFAQKIE
LPEQLYERVI EVSGRYAADG EEIEPLEIEA ARKELEVAFE SGIRSAAIVL MHAYRFPEHE
LRLGELAREI GFTQVSLSHQ ASPLIKLVSR GETTVVDAYL SPVLRRYVDM VQKTLEKGTG
AGKGKVEGHD NYAEAGKRNT RLMFMQSNGG LTDAHFFQGK DSILSGPAGG IVGAVATSAM
AGAEKIITFD MGGTSTDVAH YDGEYERSFE TEVAGVRLRS PMMRIHTVAA GGGSILHFEA
GRFRVGPDSA GADPGPACYR KGGPLTVTDC NLMLGKLQPQ FFPNLFGPEA NQPLDLEVVR
RKFGELAEQV SVGSVGSTSS PSSPPSSVEE VAEGFLSVAV ENMANAIKKI SVQRGYNVKE
YTLCCFGGAG AQHVCRIADS LGMKRIFIHP FAGVLSAYGM GLADQRLIKE HYVGTVLSDE
LTGRLESVFS GLEQEGRVEM LEQGVPEKGI AVLHKAHMRY EGSDTQLIVD FAGRKELVES
FEEAHKKRFG FIMEDKALVV EAVSVEVIGV TERVSDSVIK IDDIAEPTPI DTVRMYSYGE
YHETQVFARE ALKPGACING PAILTEKTTT IIIEPGWQAE VTEHDHLLLS RRVPLPARTS
IGTEADPVML EIFNNRFMSV AEQMGYTLQN TAHSVNIKER LDFSCAIFDR EGNLIANAPH
IPVHLGSMGE SVKALIRSKL GEMKPGDVYL INSPYQGGTH LPDITVVTPM FGKTGSAGPS
SSAGAGGNII NQAEEILFYT ASRGHHADVG GITPGSMPPG SRTIWDEGVL SEGLKIVGQG
HFYEERLRAW LNSGKHPTRN PDQNVADLRA QVAANEKGVR ELRKMVDQFS LGTVDAYMGH
VQRNAEESVR RVIDVLDDGE FSNTLDDGSA IKVKISINRE KRSACIDFTG TSPQLSNNFN
APASVCKAAV LYTFRTLVKS DIPLNAGCLK PLEIIIPPGS MLNPEPPAAV VAGNVETSQY
IVDALFGALG TMAASQGTMN NFTFGNADYQ YYETICGGAG AGPDFPGTDA VHTHMTNSRI
TDPEVLETRF PVRVEEFSIR RGSGGDGRFK GGNGTVRKIS FLKDMNAAIL SSHRKLPPFG
LKGGEPGKCG KNMIIRGNGK VLELEGQAGF EVQKGDVFVI ETPGGGGYGE RELEKLQKKI
KAGDSKK
//
