ID A0A0E8D5M5_BORPT Unreviewed; 558 AA.
AC A0A0E8D5M5;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Long-chain-fatty-acid--CoA ligase {ECO:0000256|ARBA:ARBA00039545};
DE EC=6.2.1.3 {ECO:0000256|ARBA:ARBA00026121};
DE AltName: Full=Long-chain acyl-CoA synthetase {ECO:0000256|ARBA:ARBA00042773};
GN Name=fadD_3 {ECO:0000313|EMBL:SUV66171.1};
GN ORFNames=NCTC10911_03218 {ECO:0000313|EMBL:SUV66171.1};
OS Bordetella pertussis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Bordetella.
OX NCBI_TaxID=520 {ECO:0000313|EMBL:SUV66171.1, ECO:0000313|Proteomes:UP000255014};
RN [1] {ECO:0000313|EMBL:SUV66171.1, ECO:0000313|Proteomes:UP000255014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC10911 {ECO:0000313|EMBL:SUV66171.1,
RC ECO:0000313|Proteomes:UP000255014};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
CC {ECO:0000256|ARBA:ARBA00005005}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; UFTT01000002; SUV66171.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0E8D5M5; -.
DR Proteomes; UP000255014; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004467; F:long-chain fatty acid-CoA ligase activity; IEA:UniProtKB-EC.
DR CDD; cd05936; FC-FACS_FadD_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43767:SF8; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:SUV66171.1}.
FT DOMAIN 30..421
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 472..546
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 558 AA; 60466 MW; 83147897A67ABD1C CRC64;
MLRPWLAHYP AGVPHEISPQ DYTSLTDLLD QACRRHAGQV ACRSMGSDMT YAQLDAHARH
FAAWLQGRGL ARGARVALMM PNVPAYLVCL LGTLRAGMVV VNVNPLYKAD ELQRQLLDSG
AETIVILENF AHTLQAVPDR GALSHVVVVG PGDLLGGLKA PLVNLAARYV KKLIPPWRID
GAHRLPDALR DGARATFTPP ALGMDDLAVL QYTGGTTGVP KGAMLSHGNL VANVLQTEAV
AQPVLHDLHG RQLTIISALP LYHVFAMTVC GLYGMHAGMR NLLVINPRDQ AALIVAWRQA
PINIFPGVNT LFNALVNNPD FAKLDFTDLR LTLGGGMAVQ RQVAERWLEL TGHPLIEGYG
LSETSPVATV NPTDAKTYSG SIGLPLPSTD VAILDDDGAP VPLGERGEVA IRGPQVMLGY
WQKPEETRNV MTADGFFLTG DIGIMDEAGY TRIVDRKKDM IAVSGFKVYP NEVEAVIAAH
PGVLECAVIG VPDEHSGEAV KVFVVKKDPA LTAEAVLQWC EERLTGYKRP RHVEFRDELP
KSNVGKILRR ELRPEAGS
//
