ID A0A0E9MXW6_9BACT Unreviewed; 1092 AA.
AC A0A0E9MXW6;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=FPE01S_01_12890 {ECO:0000313|EMBL:GAO42276.1};
OS Flavihumibacter petaseus NBRC 106054.
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Flavihumibacter.
OX NCBI_TaxID=1220578 {ECO:0000313|EMBL:GAO42276.1, ECO:0000313|Proteomes:UP000033121};
RN [1] {ECO:0000313|EMBL:GAO42276.1, ECO:0000313|Proteomes:UP000033121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 106054 {ECO:0000313|EMBL:GAO42276.1,
RC ECO:0000313|Proteomes:UP000033121};
RA Miyazawa S., Hosoyama A., Hashimoto M., Noguchi M., Tsuchikane K., Ohji S.,
RA Yamazoe A., Ichikawa N., Kimura A., Fujita N.;
RT "Whole genome shotgun sequence of Flavihumibacter petaseus NBRC 106054.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAO42276.1}.
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DR EMBL; BBWV01000001; GAO42276.1; -; Genomic_DNA.
DR RefSeq; WP_046367995.1; NZ_BBWV01000001.1.
DR AlphaFoldDB; A0A0E9MXW6; -.
DR STRING; 1220578.FPE01S_01_12890; -.
DR OrthoDB; 9810135at2; -.
DR Proteomes; UP000033121; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR Gene3D; 1.10.3170.10; Recbcd, chain B, domain 2; 1.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF64; ATP-DEPENDENT DNA HELICASE REP; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000033121}.
FT DOMAIN 1..465
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 502..764
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
FT REGION 899..941
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 899..914
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 11..18
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 1092 AA; 125045 MW; 549E94AC9376A612 CRC64;
MLSKPLHIYR ASAGSGKTFL LASQYLRLLF TQPQKFREIL AVTFTNKATE EMKERILGEL
EKIAEGKPTP YRAIIQAASP RLQGDQLDLA AQRIYRSILH DYSRFSVGTI DSFVQQVIRA
FAFEIGLDSG YALELNSELV KTDLAERLFR LLDTDSALRS WITDLVYDRL ADGQSWDFRQ
AMLQLADEIF KERFAFFEDN MRALEDPDKS FQQLRNNLVQ RIQPFEGKLL LLASQALECI
QSASLEPDDF RNGKRGFTAN LLKIHERREF GATDKLRKAA GNINEWITKS MDTEKKSAIE
QLFPQLDPLL QQMIEFYDAN RVDYYTALSV YRNLYNLNLL RVLAAQLANY RRENRVLLIG
DTHLLLRELV RENDTPFIFE KTGSRYQHFL IDEFQDTSTI QWENFRPLLE QTIATGQYNL
LVGDVKQAIY RWRNGDWRLL LKTVKEQLGD AVVEEGRLQD NYRSRKEIIS FNNYIFREAP
LLLQQQFNQE MAEIPDQNIF SKLESEGYFS MISDAYADSN QDMPAGVRGG GSIELELFER
PEPRSSRSWW ESAAGVLPVT IERLIREEQY SPGGIAILTR NNQDARTVID ELLHYQDAAP
DHLRYPIVSA DALLINNAPI VQLLVAAISC LNDPSDQVSR ATLVQANAIR LKQQLDDPVL
YSASKETAFA QLPDHFSNRF ENLRRMSLYD CVEALIVIFS LDTWEAEQPY LLHFRDLINA
FANKGKTTLK SFVSWWADEG DRQALPAAGG GNAVQVMTIH KSKGLAFDAV ILPFADWEFK
SEKGNIWCAL DPAIAGITWV PVKLSQQLRE TAFAFDYFEE TLFNLMDALN LLYVALTRAR
KKLVMFGPMP SKSTLENDTV KTVADLMYQL LHPAANKPVA AEWQQFWQAT RFHLHGEATS
ETIHSEHREQ PARLPASSRR QQPSWLRAAE KDRPQATTST QQEWGSLLHL ALSRIDSKQQ
IDQQLQRLLL EGKLLGSQLP ELRSGIMEVL NVPELAQWYS GGYEAMSERP ILLQGGAVRR
PDKIFIGKEE TILVDFKFTQ SLQPSHAAQL QQYRQLLEQM GYRNVKAYLY YGQQQQLVPL
ASLPGRQGNL FN
//
