ID A0A0F2L4N7_9CREN Unreviewed; 411 AA.
AC A0A0F2L4N7;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=threonine ammonia-lyase {ECO:0000256|ARBA:ARBA00012096};
DE EC=4.3.1.19 {ECO:0000256|ARBA:ARBA00012096};
GN ORFNames=TU36_01150 {ECO:0000313|EMBL:KJR72587.1};
OS Vulcanisaeta sp. AZ3.
OC Archaea; Thermoproteota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC Vulcanisaeta.
OX NCBI_TaxID=1609231 {ECO:0000313|EMBL:KJR72587.1};
RN [1] {ECO:0000313|EMBL:KJR72587.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Servin-Garciduenas L.E., Martinez-Romero E.;
RT "Metagenome Sequencing of an Archaeal-Dominated Microbial Community from a
RT Hot Spring at the Los Azufres Geothermal Field, Mexico.";
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJR72587.1}.
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DR EMBL; JZWU01000017; KJR72587.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F2L4N7; -.
DR PATRIC; fig|1609231.3.peg.420; -.
DR Proteomes; UP000054362; Unassembled WGS sequence.
DR GO; GO:0004794; F:L-threonine ammonia-lyase activity; IEA:UniProtKB-EC.
DR GO; GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0006567; P:threonine catabolic process; IEA:InterPro.
DR CDD; cd04886; ACT_ThrD-II-like; 1.
DR CDD; cd01562; Thr-dehyd; 1.
DR Gene3D; 3.30.70.260; -; 1.
DR Gene3D; 3.40.50.1100; -; 2.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR002912; ACT_dom.
DR InterPro; IPR044561; ACT_ThrD-II-like.
DR InterPro; IPR005789; Thr_deHydtase_catblc.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR NCBIfam; TIGR01127; ilvA_1Cterm; 1.
DR PANTHER; PTHR48078:SF6; ACT DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48078; THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF01842; ACT; 1.
DR Pfam; PF00291; PALP; 1.
DR SUPFAM; SSF55021; ACT-like; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
DR PROSITE; PS51671; ACT; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00023304};
KW Branched-chain amino acid biosynthesis {ECO:0000256|ARBA:ARBA00023304};
KW Isoleucine biosynthesis {ECO:0000256|ARBA:ARBA00022624};
KW Lyase {ECO:0000313|EMBL:KJR72587.1}.
FT DOMAIN 334..411
FT /note="ACT"
FT /evidence="ECO:0000259|PROSITE:PS51671"
SQ SEQUENCE 411 AA; 44307 MW; 8F32141A72612351 CRC64;
MSSADVFSRA KVALETIRDA QSKGLIYRTP LLRSETLSGI VGANVWLKLE SLQKTGSFKV
RGAYFAIKNA VERLGVKHVI TASAGNHAQG VAYAARLMGI KATVVMPEST PWIKIMRTRK
YGAEVVLHGE SYTESEAYAM KLKDEMKAYY IHAYNDPDVI AGQGTIGFEI YEDLKDVDYV
IVPVGGGGLI SGIASVIKKL KPNVKVIGVQ SDGAPGAYES LKEGRIVTIE NVDTIAEGIA
VKRIGELTFK LMSELLDDIV LVSDLEIAKA ILLIAESVKT IAEGAGAAAV AALISGKVKV
NGNVVALVSG GNIDMTMLFR VITKALALED RIKKLTGLLP DKPGTLAKVT TTLGNLGVNI
LDVFHERYDP TIKPGYVRVS FIIELPPEEE ALDKVLKELS KLNYNFTVEK A
//
