ID   A0A0F2P562_9GAMM        Unreviewed;       718 AA.
AC   A0A0F2P562;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   RecName: Full=4Fe-4S Mo/W bis-MGD-type domain-containing protein {ECO:0000259|PROSITE:PS51669};
GN   ORFNames=VR73_05350 {ECO:0000313|EMBL:KJS08496.1};
OS   Gammaproteobacteria bacterium BRH_c0.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria.
OX   NCBI_TaxID=1629722 {ECO:0000313|EMBL:KJS08496.1, ECO:0000313|Proteomes:UP000033581};
RN   [1] {ECO:0000313|EMBL:KJS08496.1, ECO:0000313|Proteomes:UP000033581}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BRH_c0 {ECO:0000313|EMBL:KJS08496.1};
RA   Bagnoud A., Chourey K., Hettich R.L., de Bruijn I., Andersson A.F.,
RA   Leupin O.X., Schwyn B., Bernier-Latmani R.;
RT   "Microbial metabolic network in the subsurface.";
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mo-bis(molybdopterin guanine dinucleotide);
CC         Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
CC   -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC       oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KJS08496.1}.
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DR   EMBL; LADM01000045; KJS08496.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0F2P562; -.
DR   STRING; 1629722.VR73_05350; -.
DR   PATRIC; fig|1629722.3.peg.3368; -.
DR   Proteomes; UP000033581; Unassembled WGS sequence.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd02775; MopB_CT; 1.
DR   Gene3D; 2.40.40.20; -; 1.
DR   Gene3D; 3.40.50.740; -; 1.
DR   Gene3D; 2.20.25.90; ADC-like domains; 1.
DR   Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR   InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR   InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR   InterPro; IPR006656; Mopterin_OxRdtase.
DR   InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR   InterPro; IPR027467; MopterinOxRdtase_cofactor_BS.
DR   PANTHER; PTHR43742:SF6; OXIDOREDUCTASE YYAE-RELATED; 1.
DR   PANTHER; PTHR43742; TRIMETHYLAMINE-N-OXIDE REDUCTASE; 1.
DR   Pfam; PF04879; Molybdop_Fe4S4; 1.
DR   Pfam; PF00384; Molybdopterin; 1.
DR   Pfam; PF01568; Molydop_binding; 1.
DR   SMART; SM00926; Molybdop_Fe4S4; 1.
DR   SUPFAM; SSF50692; ADC-like; 1.
DR   SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR   PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR   PROSITE; PS00551; MOLYBDOPTERIN_PROK_1; 1.
PE   3: Inferred from homology;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   DOMAIN          3..60
FT                   /note="4Fe-4S Mo/W bis-MGD-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51669"
SQ   SEQUENCE   718 AA;  78182 MW;  A923256919D3852C CRC64;
     MALSKHKSFC RICTGHCGVV ATVDENRKLV AIQGDREDTQ TLGFICSKGT DAVDSHNSDR
     RILQPLKRMD DGSFAPIPLE QALSEIASKL GVIIGRDGPA AVAAYRGSGG FFASASIQVV
     NAFLDAIGSH QMYSNLTIDQ SAKWVAIGRV GWWPPGPQPF QTNDVAMMVG CNPLVSIAGS
     GFDTRHPLKR IRDAKARGMK IIVIDPRRSE TAEYADLFIQ PLPGNDAGIL AAIIRIILAE
     GWHDAEFCAR HVADLDLLQQ ALEPFDPERV AAVADVPVDS LRQAARIFAH DCKRGTVSTG
     TGPSMSPFSN LMEHMVTCLN VVCGRFVREG ERIGNPGLVL GWGPKRAQVM DVGRSWDTGP
     KSRIGGFGTV GGEMLTGLLA DEILTPGPGQ IKCLFSVGGN PAAAVPDHNK MAKALESLEL
     LVSLEPFMTP TAMLADYILP PRMPYERADL HLALFETAIY PDAYARHTQP VATPPEGAEL
     CDEWFAFWSL ASRLGRQLVC NGVELDMQTP PGDDALLAIM ARNAPVPWET IRDAPAGYLH
     EEAVFALPPD PASTSRFTTL PADVQDEITE LRDYCLQPSA DRATGKFPYR LTSRRSRHRF
     NTVGHFSPYL KRLMPYNPAY LNPADMAREG IENGDWVEIS SDHGLIRARA EADDSVRTGV
     VSISHCFGFL PGESDFDTYG VSTNLLISTD RDLQTINAMP RMSGIPVAIR PMAERRLG
//