ID   A0A0F3GQ39_9BACT        Unreviewed;       433 AA.
AC   A0A0F3GQ39;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Lysine 2,3-aminomutase YodO family protein {ECO:0000313|EMBL:KJU84050.1};
GN   ORFNames=MBAV_003755 {ECO:0000313|EMBL:KJU84050.1};
OS   Candidatus Magnetobacterium bavaricum.
OC   Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
OC   Magnetobacterium.
OX   NCBI_TaxID=29290 {ECO:0000313|EMBL:KJU84050.1, ECO:0000313|Proteomes:UP000033423};
RN   [1] {ECO:0000313|EMBL:KJU84050.1, ECO:0000313|Proteomes:UP000033423}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TM-1 {ECO:0000313|EMBL:KJU84050.1};
RA   Kolinko S., Richter M., Glockner F.O., Brachmann A., Schuler D.;
RT   "Single-cell genomics of uncultivated deep-branching MTB reveals a
RT   conserved set of magnetosome genes.";
RL   Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|PIRSR:PIRSR603739-50};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KJU84050.1}.
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DR   EMBL; LACI01001636; KJU84050.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0F3GQ39; -.
DR   PATRIC; fig|29290.4.peg.4997; -.
DR   Proteomes; UP000033423; Unassembled WGS sequence.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd01335; Radical_SAM; 1.
DR   Gene3D; 6.10.140.1170; -; 1.
DR   Gene3D; 6.20.120.40; -; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR025895; LAM_C_dom.
DR   InterPro; IPR003739; Lys_aminomutase/Glu_NH3_mut.
DR   InterPro; IPR007197; rSAM.
DR   NCBIfam; TIGR00238; KamA family radical SAM protein; 1.
DR   PANTHER; PTHR30538:SF1; L-LYSINE 2,3-AMINOMUTASE; 1.
DR   PANTHER; PTHR30538; LYSINE 2,3-AMINOMUTASE-RELATED; 1.
DR   Pfam; PF13353; Fer4_12; 1.
DR   Pfam; PF12544; LAM_C; 1.
DR   Pfam; PF04055; Radical_SAM; 1.
DR   PIRSF; PIRSF004911; DUF160; 1.
DR   SFLD; SFLDG01070; PLP-dependent; 1.
DR   SFLD; SFLDS00029; Radical_SAM; 1.
DR   SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR   PROSITE; PS51918; RADICAL_SAM; 1.
PE   4: Predicted;
KW   4Fe-4S {ECO:0000256|PIRSR:PIRSR004911-1};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014, ECO:0000256|PIRSR:PIRSR004911-
KW   1}; Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|PIRSR:PIRSR004911-1};
KW   Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR603739-50};
KW   Reference proteome {ECO:0000313|Proteomes:UP000033423};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT   DOMAIN          136..347
FT                   /note="Radical SAM core"
FT                   /evidence="ECO:0000259|PROSITE:PS51918"
FT   BINDING         150
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR004911-1"
FT   BINDING         154
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR004911-1"
FT   BINDING         157
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR004911-1"
FT   MOD_RES         362
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR603739-50"
SQ   SEQUENCE   433 AA;  49674 MW;  DCC6A59BB4C2D009 CRC64;
     MLKVYNKSCR GTMENDCLLK EEEPPAQGIL RRFWPDVTSR QWNDWRWQQS NSLRSVQALR
     ELLNLSTHEV LRYEELTRRF HYCITPYYLS LIDFTNPDDP IRKQSIPDIS ELDFQRVGHS
     DPLEEGEDTQ VPGLVHRYPD RALAVVTSRC AMYCRHCTRK RMWHEGESFR TRQELAAMVD
     YIRGEPGIRE VIVSGGDPLT MNLRLLDWFL GELRTAPSLE VIRIGTRMPV VMPMGITDDL
     VRMLARHRPL WLNTQFNHPA ELTPASIEAC DKILRAGIPV SNQSVLLRGV NDSVEVMKEL
     CHALQRIMVR PYYLFQCDPV IGVEHFRTSI WKGIEIIEMM RGHTGGLCIP SFVVDAPGGG
     GKVPLQPFYL LSASEDEVLL RNYEGTIIRY YNPGRSLTEA GQESGAQQTH RILAGTDITA
     RYKRRRSKAA LAH
//