ID   A0A0F4IX52_9ACTN        Unreviewed;       255 AA.
AC   A0A0F4IX52;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   SubName: Full=IclR family transcriptional regulator {ECO:0000313|EMBL:KJY25261.1};
GN   ORFNames=VR44_32990 {ECO:0000313|EMBL:KJY25261.1};
OS   Streptomyces katrae.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=68223 {ECO:0000313|EMBL:KJY25261.1, ECO:0000313|Proteomes:UP000033551};
RN   [1] {ECO:0000313|EMBL:KJY25261.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL ISP-5550 {ECO:0000313|EMBL:KJY25261.1};
RA   Ju K.-S., Doroghazi J.R., Metcalf W.;
RL   Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KJY25261.1}.
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DR   EMBL; JZWV01001100; KJY25261.1; -; Genomic_DNA.
DR   RefSeq; WP_045951309.1; NZ_JZWV01001100.1.
DR   AlphaFoldDB; A0A0F4IX52; -.
DR   STRING; 68223.GCA_002028425_01577; -.
DR   PATRIC; fig|68223.7.peg.3418; -.
DR   eggNOG; COG1414; Bacteria.
DR   OrthoDB; 4474604at2; -.
DR   Proteomes; UP000033551; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR   InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR   PANTHER; PTHR30136:SF24; HTH-TYPE TRANSCRIPTIONAL REPRESSOR ALLR; 1.
DR   Pfam; PF09339; HTH_IclR; 1.
DR   Pfam; PF01614; IclR; 1.
DR   SMART; SM00346; HTH_ICLR; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51077; HTH_ICLR; 1.
DR   PROSITE; PS51078; ICLR_ED; 1.
PE   4: Predicted;
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          5..67
FT                   /note="HTH iclR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51077"
FT   DOMAIN          68..252
FT                   /note="IclR-ED"
FT                   /evidence="ECO:0000259|PROSITE:PS51078"
SQ   SEQUENCE   255 AA;  27276 MW;  60F76C26555C630A CRC64;
     MARNIQSLER AAAMLRLLAG GERRLGLSDV ASALGLAKGT AHGILRTLQA EGFVEQDPAS
     GRYQLGAELL RLGNSYLDVH ELRARALVWT DDLARASGES VYVGVLHKSG VLIMHHVFRP
     DDSRQVLEVG AMQPLHSTAL GKVLSAYDPV AHTEALDAER EAFTPRTVTD AAGFEEVLDL
     TRARGWAADV EETWEGLASV AAPIHDRRRM PVGAVAVAGA VERVCGESGE PRPALVAAVR
     DCARSVSRDL GAGRF
//