ID A0A0F4PKL8_9GAMM Unreviewed; 70 AA.
AC A0A0F4PKL8;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Heme exporter protein D {ECO:0000256|ARBA:ARBA00016461, ECO:0000256|RuleBase:RU363101};
GN Name=ccmD {ECO:0000313|EMBL:TMP87972.1};
GN ORFNames=CWC05_04775 {ECO:0000313|EMBL:TMP87972.1}, TW72_16250
GN {ECO:0000313|EMBL:KJY96768.1};
OS Pseudoalteromonas ruthenica.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Pseudoalteromonadaceae; Pseudoalteromonas.
OX NCBI_TaxID=151081 {ECO:0000313|EMBL:KJY96768.1, ECO:0000313|Proteomes:UP000033664};
RN [1] {ECO:0000313|EMBL:KJY96768.1, ECO:0000313|Proteomes:UP000033664}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S3137 {ECO:0000313|EMBL:KJY96768.1,
RC ECO:0000313|Proteomes:UP000033664};
RX PubMed=25879706; DOI=10.1186/s12864-015-1365-z;
RA Machado H., Sonnenschein E.C., Melchiorsen J., Gram L.;
RT "Genome mining reveals unlocked bioactive potential of marine Gram-negative
RT bacteria.";
RL BMC Genomics 16:158-158(2015).
RN [2] {ECO:0000313|EMBL:TMP87972.1, ECO:0000313|Proteomes:UP000305874}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S2897 {ECO:0000313|EMBL:TMP87972.1,
RC ECO:0000313|Proteomes:UP000305874};
RA Paulsen S., Gram L.K.;
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000305874}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S2897 {ECO:0000313|Proteomes:UP000305874};
RA Sonnenschein E.C., Bech P.K.;
RT "Co-occurence of chitin degradation, pigmentation and bioactivity in marine
RT Pseudoalteromonas.";
RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:TMP87972.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=S2897 {ECO:0000313|EMBL:TMP87972.1};
RA Sonnenschein E.C., Bech P.K.;
RT "Co-occurence of chitin degradation, pigmentation and bioactivity in marine
RT Pseudoalteromonas.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for the export of heme to the periplasm for the
CC biogenesis of c-type cytochromes. {ECO:0000256|ARBA:ARBA00002442,
CC ECO:0000256|RuleBase:RU363101}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004377, ECO:0000256|RuleBase:RU363101}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004377,
CC ECO:0000256|RuleBase:RU363101}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the CcmD/CycX/HelD family.
CC {ECO:0000256|ARBA:ARBA00008741, ECO:0000256|RuleBase:RU363101}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJY96768.1}.
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DR EMBL; JXXZ01000015; KJY96768.1; -; Genomic_DNA.
DR EMBL; PNCG01000003; TMP87972.1; -; Genomic_DNA.
DR RefSeq; WP_022944768.1; NZ_PPSV01000025.1.
DR AlphaFoldDB; A0A0F4PKL8; -.
DR STRING; 151081.TW72_16250; -.
DR GeneID; 58230053; -.
DR PATRIC; fig|151081.8.peg.2639; -.
DR eggNOG; COG3114; Bacteria.
DR OrthoDB; 9815607at2; -.
DR Proteomes; UP000033664; Unassembled WGS sequence.
DR Proteomes; UP000305874; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR GO; GO:0015886; P:heme transport; IEA:InterPro.
DR InterPro; IPR007078; Haem_export_protD_CcmD.
DR NCBIfam; TIGR03141; cytochro_ccmD; 1.
DR PANTHER; PTHR37531; HEME EXPORTER PROTEIN D; 1.
DR PANTHER; PTHR37531:SF1; HEME EXPORTER PROTEIN D; 1.
DR Pfam; PF04995; CcmD; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|RuleBase:RU363101};
KW Cell membrane {ECO:0000256|RuleBase:RU363101};
KW Cytochrome c-type biogenesis {ECO:0000256|RuleBase:RU363101};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363101};
KW Reference proteome {ECO:0000313|Proteomes:UP000033664};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363101};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363101}; Transport {ECO:0000256|RuleBase:RU363101}.
FT TRANSMEM 15..39
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363101"
SQ SEQUENCE 70 AA; 7953 MW; 6463A3E940B79AB8 CRC64;
MEFNSFSEFL AMGGYGFYVW LSFGSCAFIL IALLVTSLLE KRNVLKQVAA QSAREQRIER
AKRSQQESSL
//
