ID A0A0F4QUD4_9GAMM Unreviewed; 319 AA.
AC A0A0F4QUD4;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein {ECO:0000259|Pfam:PF01073};
GN ORFNames=TW85_19185 {ECO:0000313|EMBL:KJZ10845.1};
OS Marinomonas sp. S3726.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Marinomonas.
OX NCBI_TaxID=579484 {ECO:0000313|EMBL:KJZ10845.1, ECO:0000313|Proteomes:UP000033747};
RN [1] {ECO:0000313|EMBL:KJZ10845.1, ECO:0000313|Proteomes:UP000033747}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S3726 {ECO:0000313|EMBL:KJZ10845.1,
RC ECO:0000313|Proteomes:UP000033747};
RX PubMed=25879706; DOI=10.1186/s12864-015-1365-z;
RA Machado H., Sonnenschein E.C., Melchiorsen J., Gram L.;
RT "Genome mining reveals unlocked bioactive potential of marine Gram-negative
RT bacteria.";
RL BMC Genomics 16:158-158(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJZ10845.1}.
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DR EMBL; JXYC01000025; KJZ10845.1; -; Genomic_DNA.
DR RefSeq; WP_052702304.1; NZ_JXYC01000025.1.
DR AlphaFoldDB; A0A0F4QUD4; -.
DR PATRIC; fig|579484.3.peg.3938; -.
DR Proteomes; UP000033747; Unassembled WGS sequence.
DR GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR48079; PROTEIN YEEZ; 1.
DR PANTHER; PTHR48079:SF6; PROTEIN YEEZ; 1.
DR Pfam; PF01073; 3Beta_HSD; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000033747}.
FT DOMAIN 5..250
FT /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF01073"
SQ SEQUENCE 319 AA; 35592 MW; 38267B2454A1F888 CRC64;
MKIFITGITG YVGRNLAKHF VKKHEVAGLS RDLEKSLNLE ELGIEIFKGD LHSSCLEKEL
KSYDVVIHAA ADTDHKNASR SQYDTNVVGT ELLLHAAKAA GVKKFIHIST ESVLLTGKEL
HLAKENIPYP KVSVGSYSET KRLAEELALK SSNDEFNVIV LRPRFIWGRD DTTAIPQILK
AVNNGQFAWI NDGEYKTSTI HIANFCFGVE CAISRGNSGE VYFLSDDDDK TFKNIVSALI
EAYGYRSPTK SVPRAMLLFI AKLDNCCRKL FPKRKLLPIT MQEYSTSAVE ITLDISKAKK
ELGYAPVISF QQGLLEITR
//
